Research output per year
Research output per year
Unit profile
Description
Björn Nilsson is Research Group Leader for this research groupResearch
Our research group combines mathematics and genomics to address clinically important problems in hematology and immunology. Current projects focus on blood cell formation and blood disorders, e.g. multiple myeloma and childhood leukemia. The team of computer scientists, clinicians, and molecular biologists work closely together. Computational models are combined with genetic approaches to identify risk genes for blood- and immunological disorders, as well as regulators of the cell functions. Our network of international collaborations include deCODE Genetics and the Broad Institute. Our research has contributed to the understanding of inherited susceptibility to multiple myeloma, the identification of the gene behind the Vel-blood group and a diagnostic tool for the blood group used in clinical practice. Sources of funding include e.g. the Swedish foundation for Strategic Research, the Knut and Alice Wallenberg Foundation, The Swedish Childhood Cancer Foundation and Swedish Research Council.UKÄ subject classification
- Cancer and Oncology
- Immunology in the medical area
- Immunology
- Bioinformatics (Computational Biology)
- Medical Genetics
- Hematology
- Cell and Molecular Biology
- Clinical Laboratory Medicine
Free keywords
- Multiple myeloma
- leukemia
- ALL
- AML
- CRISPR/Cas9
- shRNA
- Flow cytometry
- blood cell formation
- population genetics
- hematology
- genomics
- computional biology
- bioinformatics
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Ram Ajore
- Division of Hematology and Transfusion Medicine - Laboratory researcher
- Hematogenomics - Laboratory researcher
- LUCC: Lund University Cancer Centre - Researcher
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Assistant researcher
Person
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Zain Ali
- Hematogenomics - Doctoral student
- Division of Hematology and Transfusion Medicine - Doctoral student
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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Caterina Cafaro
- Hematogenomics - Research engineer
- Division of Hematology and Transfusion Medicine - Research engineer
- LUCC: Lund University Cancer Centre - Research support
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Research engineer
Person
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A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic data sets
Vlasschaert, C., Mack, T., Heimlich, J. B., Niroula, A., Uddin, M. M., Weinstock, J., Sharber, B., Silver, A. J., Xu, Y., Savona, M., Gibson, C., Lanktree, M. B., Rauh, M. J., Ebert, B. L., Natarajan, P., Jaiswal, S. & Bick, A. G., 2023, In: Blood. 141, 18, p. 2214-2223 10 p.Research output: Contribution to journal › Article › peer-review
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Ciclopirox Ethanolamine Preserves the Immature State of Human HSCs by Mediating Intracellular Iron Content
Safaee Talkhoncheh, M., Baudet, A., Ek, F., Subramaniam, A., Kao, Y-R., Miharada, N., Karlsson, C., Oburoglu, L., Rydström, A., Žemaitis, K., Alattar, A. G., Rak, J., Pietras, K., Olsson, R., Will, B. & Larsson, J., 2023 Jul 24, (E-pub ahead of print) In: Blood Advances.Research output: Contribution to journal › Article › peer-review
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Clinical characteristics and outcome of 318 families with familial monoclonal gammopathy: A multicenter Intergroupe Francophone du Myélome study
Dumontet, C., Demangel, D., Galia, P., Karlin, L., Roche, L., Fauvernier, M., Golfier, C., Laude, M. C., Leleu, X., Rodon, P., Roussel, M., Azaïs, I., Doyen, C., Slama, B., Manier, S., Decaux, O., Pertesi, M., Beaumont, M., Caillot, D., Boyle, E. M., & 19 others, 2023 Feb, In: American Journal of Hematology. 98, 2, p. 264-271 8 p.Research output: Contribution to journal › Article › peer-review
Open Access
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Understanding the mechanisms of blood cancer development: Large-scale genetic study of clonal hematopoiesis in human genomes
2022/07/01 → 2028/06/30
Project: Research
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Computational studies on the effects of genetic variation in hematopoiesis
2022/02/01 → 2026/01/31
Project: Dissertation
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Activities
- 1 Organisation of workshop/ seminar/ course
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Social Resilience Seminar: From Publications to Public Actions
Patric Nordbeck (Organiser), Aitzkoa Lopez de Lapuente Portilla (Organiser) & Laura Horn (Invited speaker)
2022 Sept 7Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course