Research output per year
Research output per year
- 1 - 50 out of 90 results
Search results
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2022
A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function
Bahnan, W., Happonen, L., Khakzad, H., Kumra Ahnlide, V., de Neergaard, T., Wrighton, S., André, O., Bratanis, E., Tang, D., Hellmark, T., Björck, L., Shannon, O., Malmström, L., Malmström, J. & Nordenfelt, P., 2022 Dec 12, (E-pub ahead of print) In: EMBO Molecular Medicine. e16208.Research output: Contribution to journal › Article › peer-review
Open Access -
Distinct Serotypes of Streptococcal M Proteins Mediate Fibrinogen-Dependent Platelet Activation and Proinflammatory Effects
Palm, F., Chowdhury, S., Wettemark, S., Malmström, J., Happonen, L. & Shannon, O., 2022, In: Infection and Immunity. 90, 2, p. 1-12 e00462-21.Research output: Contribution to journal › Article › peer-review
Open Access -
Effective protein extraction combined with data independent acquisition analysis reveals a comprehensive and quantifiable insight into the proteomes of articular cartilage and subchondral bone
Bundgaard, L., Åhrman, E., Malmström, J., Keller, U. A. D., Walters, M. & Jacobsen, S., 2022, In: Osteoarthritis and Cartilage. 30, 1, p. 137-146Research output: Contribution to journal › Article › peer-review
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Interaction of Bartonella henselae with Fibronectin Represents the Molecular Basis for Adhesion to Host Cells
Vaca, D. J., Thibau, A., Leisegang, M. S., Malmström, J., Linke, D., Eble, J. A., Ballhorn, W., Schaller, M., Happonen, L. & Kempf, V. A. J., 2022 Jun 29, In: Microbiology spectrum. 10, 3, e0059822.Research output: Contribution to journal › Article › peer-review
Open Access -
Invasive Streptococcal Infection Can Lead to the Generation of Cross-Strain Opsonic Antibodies
de Neergaard, T., Bläckberg, A., Ivarsson, H., Thomasson, S., Kumra Ahnlide, V., Chowdhury, S., Khakzad, H., Bahnan, W., Malmström, J., Rasmussen, M. & Nordenfelt, P., 2022 Dec 21, In: Microbiology spectrum. 10, 6, e0248622.Research output: Contribution to journal › Article › peer-review
Open Access -
Landscape of surfaceome and endocytome in human glioma is divergent and depends on cellular spatial organization
Governa, V., Talbot, H., Gonçalves de Oliveira, K., Cerezo-Magaña, M., Bång-Rudenstam, A., Johansson, M. C., Månsson, A-S., Forsberg-Nilsson, K., Marko-Varga, G., Enríquez Pérez, J., Darabi, A., Malmström, J., Bengzon, J., Welinder, C. & Belting, M., 2022 Mar 1, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 9, p. 1-11 e2114456119.Research output: Contribution to journal › Article › peer-review
Open Access -
Long-Read Sequencing Reveals Genetic Adaptation of Bartonella Adhesin A Among Different Bartonella henselae Isolates
Thibau, A., Hipp, K., Vaca, D. J., Chowdhury, S., Malmström, J., Saragliadis, A., Ballhorn, W., Linke, D. & Kempf, V. A. J., 2022, In: Frontiers in Microbiology. 13, 838267.Research output: Contribution to journal › Article › peer-review
Open Access -
MSLibrarian: Optimized Predicted Spectral Libraries for Data-Independent Acquisition Proteomics
Isaksson, M., Karlsson, C., Laurell, T., Kirkeby, A. & Heusel, M., 2022 Jan 19, In: Journal of Proteome Research. 21, 2, p. 535-546 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Spike-Dependent Opsonization Indicates Both Dose-Dependent Inhibition of Phagocytosis and That Non-Neutralizing Antibodies Can Confer Protection to SARS-CoV-2
Bahnan, W., Wrighton, S., Sundwall, M., Bläckberg, A., Larsson, O., Höglund, U., Khakzad, H., Godzwon, M., Walle, M., Elder, E., Strand, A. S., Happonen, L., André, O., Ahnlide, J. K., Hellmark, T., Wendel-Hansen, V., Wallin, R. P., Malmstöm, J., Malmström, L., Ohlin, M., & 2 others, 2022 Jan 14, In: Frontiers in Immunology. 12, 808932.Research output: Contribution to journal › Article › peer-review
Open Access -
Vascular Proteome Responses Precede Organ Dysfunction in a Murine Model of Staphylococcus aureus Bacteremia
Sorrentino, J. T., Golden, G. J., Morris, C., Painter, C. D., Nizet, V., Campos, A. R., Smith, J. W., Karlsson, C., Malmström, J., Lewis, N. E., Esko, J. D. & Gómez Toledo, A., 2022 Aug 30, In: mSystems. 7, 4, e0039522.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
A Systems View of the Heparan Sulfate Interactome
Gómez Toledo, A., Sorrentino, J. T., Sandoval, D. R., Malmström, J., Lewis, N. E. & Esko, J. D., 2021 Feb, In: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 69, 2, p. 105-119Research output: Contribution to journal › Article › peer-review
Open Access -
Cerebrospinal fluid proteome maps detect pathogen-specific host response patterns in meningitis
Bakochi, A., Mohanty, T., Pyl, P. T., Gueto-Tettay, C. A., Malmström, L., Linder, A. & Malmström, J., 2021, In: eLife. 10, e64159.Research output: Contribution to journal › Article › peer-review
Open Access -
Cheetah-MS: a web server to model protein complexes using tandem cross-linking mass spectrometry data
Khakzad, H., Happonen, L., Malmström, J. & Malmström, L., 2021, In: Bioinformatics (Oxford, England). 37, 24, p. 4871-4872 2 p.Research output: Contribution to journal › Article › peer-review
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Citrullination of extracellular histone H3.1 reduces antibacterial activity and exacerbates its proteolytic degradation
Tanner, L., Bhongir, R. K. V., Karlsson, C. A. Q., Le, S., Ljungberg, J. K., Andersson, P., Andersson, C., Malmström, J., Egesten, A. & Single, A. B., 2021, In: Journal of Cystic Fibrosis. 20, 2, p. 346-355Research output: Contribution to journal › Article › peer-review
Open Access -
Endothelial Heparan Sulfate Mediates Hepatic Neutrophil Trafficking and Injury during Staphylococcus aureus Sepsis
Golden, G. J., Toledo, A. G., Marki, A., Sorrentino, J. T., Morris, C., Riley, R. J., Spliid, C., Chen, Q., Cornax, I., Lewis, N. E., Varki, N., Malmström, J. & Karlsson, C., 2021, In: mBio. 12, 5, e01181-21.Research output: Contribution to journal › Article › peer-review
Open Access -
Extending the Proteomic Characterization of Candida albicans Exposed to Stress and Apoptotic Inducers through Data-Independent Acquisition Mass Spectrometry
Amador-García, A., Zapico, I., Borrajo, A., Malmström, J., Monteoliva, L. & Gil, C., 2021 Oct 5, In: mSystems. 6, 5, e00946-21.Research output: Contribution to journal › Article › peer-review
Open Access -
In vivo Cross-Linking MS of the Complement System MAC Assembled on Live Gram-Positive Bacteria
Khakzad, H., Happonen, L., Tran Van Nhieu, G., Malmström, J. & Malmström, L., 2021 Jan 8, In: Frontiers in Genetics. 11, 612475.Research output: Contribution to journal › Article › peer-review
Open Access -
Multinodal Acoustic Trapping Enables High Capacity and High Throughput Enrichment of Extracellular Vesicles and Microparticles in miRNA and MS Proteomics Studies
Broman, A., Lenshof, A., Evander, M., Happonen, L., Ku, A., Malmström, J. & Laurell, T., 2021 Mar 2, In: Analytical Chemistry. 93, 8, p. 3929-3937Research output: Contribution to journal › Article › peer-review
Open Access -
PCprophet: a framework for protein complex prediction and differential analysis using proteomic data
Fossati, A., Li, C., Uliana, F., Wendt, F., Frommelt, F., Sykacek, P., Heusel, M., Hallal, M., Bludau, I., Capraz, T., Xue, P., Song, J., Wollscheid, B., Purcell, A. W., Gstaiger, M. & Aebersold, R., 2021, In: Nature Methods. 18, 5, p. 520-527 8 p.Research output: Contribution to journal › Article › peer-review
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Protein signatures of remodeled airways in transplanted lungs with Bronchiolitis Obliterans Syndrome obtained using laser capture microdissection
Müller, C., Rosmark, O., Åhrman, E., Brunnström, H., Wassilew, K., Nybom, A., Michaliková, B., Larsson, H., Eriksson, L. T., Schultz, H. H., Perch, M., Malmström, J., Wigén, J., Iversen, M. & Westergren-Thorsson, G., 2021 Aug 1, In: American Journal of Pathology. 191, 8, p. 1398-1411 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Proteogenomic Workflow Reveals Molecular Phenotypes Related to Breast Cancer Mammographic Appearance
De Marchi, T., Pyl, P. T., Sjöström, M., Klasson, S., Sartor, H., Tran, L., Pekar, G., Malmström, J., Malmström, L. & Niméus, E., 2021, In: Journal of Proteome Research. 20, 5, p. 2983-3001 19 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Proteome profiling of recombinant DNase therapy in reducing NETs and aiding recovery in COVID-19 patients
Fisher, J., Mohanty, T., Karlsson, C., Khademi, S. M. H., Malmström, E., Frigyesi, A., Nordenfelt, P., Malmstrom, J. & Linder, A., 2021, In: Molecular and Cellular Proteomics. 20, 100113.Research output: Contribution to journal › Article › peer-review
Open Access -
Quantitative proteomic analysis of human peripheral nerves from subjects with type 2 diabetes
Ising, E., Åhrman, E., Thomsen, N. O. B., Eriksson, K-F., Malmström, J. & Dahlin, L. B., 2021, In: Diabetic Medicine: A journal of the British Diabetic Association. 38, 11Research output: Contribution to journal › Article › peer-review
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Streptococcal protein SIC activates monocytes and induces inflammation
Neumann, A., Happonen, L., Karlsson, C., Bahnan, W., Frick, I. M. & Björck, L., 2021 Apr 23, In: iScience. 24, 4, 102339.Research output: Contribution to journal › Article › peer-review
Open Access -
Streptococcus pyogenes Forms Serotype- and Local Environment-Dependent Interspecies Protein Complexes
Chowdhury, S., Khakzad, H., Bergdahl, G. E., Lood, R., Ekstrom, S., Linke, D., Malmström, L., Happonen, L. & Malmström, J., 2021, In: mSystems. 6, 5, p. 1-19 e0027121.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology
Khakzad, H., Happonen, L., Karami, Y., Chowdhury, S., Bergdahl, G. E., Nilges, M., Tran Van Nhieu, G., Malmström, J. & Malmström, L., 2021 Jan 7, In: PLoS Computational Biology. 17, 1, e1008169.Research output: Contribution to journal › Article › peer-review
Open Access -
Systematic detection of functional proteoform groups from bottom-up proteomic datasets
Bludau, I., Frank, M., Dörig, C., Cai, Y., Heusel, M., Rosenberger, G., Picotti, P., Collins, B. C., Röst, H. & Aebersold, R., 2021 Dec, In: Nature Communications. 12, 1, 3810.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeted selected reaction monitoring verifies histology specific peptide signatures in epithelial ovarian cancer
Liljedahl, L., Malmström, J., Kristjansdottir, B., Waldemarson, S. & Sundfeldt, K., 2021 Nov 1, In: Cancers. 13, 22, 5713.Research output: Contribution to journal › Article › peer-review
Open Access -
Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma
Cuello, H. A., Ferreira, G. M., Gulino, C. A., Toledo, A. G., Segatori, V. I. & Gabri, M. R., 2021, In: Oncotarget. 11, 35, p. 4822-4835 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The specificity of the malarial VAR2CSA protein for chondroitin sulfate depends on 4-O-sulfation and ligand accessibility
Spliid, C. B., Toledo, A. G., Sanderson, P., Mao, Y., Gatto, F., Gustavsson, T., Choudhary, S., Saldanha, A. L., Vogelsang, R. P., Gögenur, I., Theander, T. G., Leach, F. E., Amster, I. J., Esko, J. D., Salanti, A. & Clausen, T. M., 2021, In: Journal of Biological Chemistry. 297, 6, 101391.Research output: Contribution to journal › Article › peer-review
Open Access -
The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms
Hasan, M., Khakzad, H., Happonen, L., Sundin, A., Unge, J., Mueller, U., Malmström, J., Westergren-Thorsson, G., Malmström, L., Ellervik, U., Malmström, A. & Tykesson, E., 2021 Feb 7, In: Chemical Science. 12, 5, p. 1869-1885 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
A Global Screen for Assembly State Changes of the Mitotic Proteome by SEC-SWATH-MS
Heusel, M., Frank, M., Köhler, M., Amon, S., Frommelt, F., Rosenberger, G., Bludau, I., Aulakh, S., Linder, M. I., Liu, Y., Collins, B. C., Gstaiger, M., Kutay, U. & Aebersold, R., 2020, In: Cell systems. 10, 2, p. 133-155.e6Research output: Contribution to journal › Article › peer-review
Open Access -
Complex-centric proteome profiling by SEC-SWATH-MS for the parallel detection of hundreds of protein complexes
Bludau, I., Heusel, M., Frank, M., Rosenberger, G., Hafen, R., Banaei-Esfahani, A., van Drogen, A., Collins, B. C., Gstaiger, M. & Aebersold, R., 2020, In: Nature Protocols. 15, 8, p. 2341-2386 46 p.Research output: Contribution to journal › Article › peer-review
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Targeted mass spectrometry for Serum Amyloid A (SAA) isoform profiling in sequential blood samples from experimentally Staphylococcus aureus infected pigs
Leuchsenring, A. B., Karlsson, C., Bundgaard, L., Malmström, J. & Heegaard, P. M. H., 2020, In: Journal of Proteomics. 103904.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
A quantitative Streptococcus pyogenes-human protein-protein interaction map reveals localization of opsonizing antibodies
Happonen, L., Hauri, S., Svensson Birkedal, G., Karlsson, C., de Neergaard, T., Khakzad, H., Nordenfelt, P., Wikström, M., Wisniewska, M., Björck, L., Malmström, L. & Malmström, J., 2019 Jun 21, In: Nature Communications. 10, 1, p. 2727Research output: Contribution to journal › Article › peer-review
Open Access -
Comparison of Normal and Metaplastic Epithelium in Patients with Stable versus Persistently Symptomatic Severe Asthma Using Laser-Capture Microdissection and Data-Independent Acquisition–Mass Spectrometry
Weitoft, M., Müller, C., Åhrman, E., Bjermer, L., Hoffmann, H. J., Erjefält, J. & Westergren-Thorsson, G., 2019, In: American Journal of Pathology. 189, 12, p. 2358-2365 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Complement Activation Occurs at the Surface of Platelets Activated by Streptococcal M1 Protein and This Results in Phagocytosis of Platelets
Palm, F., Sjöholm, K., Malmström, J. & Shannon, O., 2019 Jan 15, In: Journal of immunology. 202, 2, p. 503-513 11 p.Research output: Contribution to journal › Article › peer-review
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Greedy de novo motif discovery to construct motif repositories for bacterial proteomes
Khakzad, H., Malmström, J. & Malmström, L., 2019 Apr 18, In: BMC Bioinformatics. 20, Suppl 4, 141.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of two abundant Aerococcus urinae cell wall-anchored proteins
Senneby, E., Sunnerhagen, T., Hallström, B., Lood, R., Malmström, J., Karlsson, C. & Rasmussen, M., 2019, In: International Journal of Medical Microbiology. 309, 7, 151325.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
Matrisome Properties of Scaffolds Direct Fibroblasts in Idiopathic Pulmonary Fibrosis
Elowsson Rendin, L., Löfdahl, A., Åhrman, E., Müller, C., Notermans, T., Michaliková, B., Rosmark, O., Zhou, X-H., Dellgren, G., Silverborn, M., Bjermer, L., Malmström, A., Larsson-Callerfelt, A-K., Isaksson, H., Malmström, J. & Westergren-Thorsson, G., 2019 Aug 17, In: International Journal of Molecular Sciences. 20, 16Research output: Contribution to journal › Article › peer-review
Open Access -
Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
Mohanty, T., Fisher, J., Bakochi, A., Neumann, A., Cardoso, J. F. P., Karlsson, C. A. Q., Pavan, C., Lundgaard, I., Nilson, B., Reinstrup, P., Bonnevier, J., Cederberg, D., Malmström, J., Bentzer, P. & Linder, A., 2019 Apr 10, In: Nature Communications. 10, 1, p. 1667Research output: Contribution to journal › Article › peer-review
Open Access -
Rapid determination of quaternary protein structures in complex biological samples
Hauri, S., Khakzad, H., Happonen, L., Teleman, J., Malmström, J. & Malmström, L., 2019 Jan 14, In: Nature Communications. 10, 192.Research output: Contribution to journal › Article › peer-review
Open Access -
Streptococcus pyogenes evades adaptive immunity through specific IgG glycan hydrolysis
Nägeli, A., Bratanis, E., Karlsson, C., Shannon, O., Kalluru, R., Linder, A., Malmström, J. & Collin, M., 2019 Jul 1, In: Journal of Experimental Medicine. 216, 7, p. 1615-1629Research output: Contribution to journal › Article › peer-review
Open AccessFile182 Downloads (Pure) -
The Human Salivary Antimicrobial Peptide Profile according to the Oral Microbiota in Health, Periodontitis and Smoking
Grant, M., Kilsgård, O., Åkerman, S., Klinge, B., Demmer, R. T., Malmström, J. & Jönsson, D., 2019, In: Journal of Innate Immunity. 11, 5, p. 432-444Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Comprehensive Mass Spectrometric Survey of Streptococcus pyogenes Subcellular Proteomes
Wilk, L., Happonen, L., Malmström, J. & Herwald, H., 2018 Jan 5, In: Journal of Proteome Research. 17, 1, p. 600-617Research output: Contribution to journal › Article › peer-review
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Leucocyte recruitment and molecular fortification of keratinocytes triggered by streptococcal M1 protein
Persson, S. T., Hauri, S., Malmström, J. & Herwald, H., 2018, In: Cellular Microbiology. 20, 1, e12792.Research output: Contribution to journal › Article › peer-review
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Platelet activation and aggregation by the opportunistic pathogen Cutibacterium (Propionibacterium) acnes
Petersson, F., Kilsgård, O., Shannon, O. & Lood, R., 2018 Jan 1, In: PLoS ONE. 13, 1, e0192051.Research output: Contribution to journal › Article › peer-review
Open Access -
Quantitative proteomic characterization of the lung extracellular matrix in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
Åhrman, E., Hallgren, O., Malmström, L., Hedström, U., Malmström, A., Bjermer, L., Zhou, X. H., Westergren-Thorsson, G. & Malmström, J., 2018, In: Journal of Proteomics. 189, p. 23-33Research output: Contribution to journal › Article › peer-review
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Streptococcal inhibitor of complement (SIC) modulates fibrinolysis and enhances bacterial survival within fibrin clots
Frick, I. M., Shannon, O., Neumann, A., Karlsson, C., Wikström, M. & Björck, L., 2018, In: Journal of Biological Chemistry. 293, 35, p. 13578-13591 14 p.Research output: Contribution to journal › Article › peer-review
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Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS
Karlsson, C. A. Q., Järnum, S., Winstedt, L., Kjellman, C., Björck, L., Linder, A. & Malmström, J. A., 2018 Jun 1, In: Molecular and Cellular Proteomics. 17, 6, p. 1097-1111Research output: Contribution to journal › Article › peer-review
Open Access