Unit profile
Description
Osteoarthritis (OA) is the most frequently occurring joint disease and is characterized by a gradual degradation of joint cartilage as well as pain and loss of function. The disease progression is slow; degradation of cartilage occurs for several years prior to symptoms. Radiological changes occur much later in the process. According to current evidence-based guidelines, the primary treatment is physiotherapy and information, preferably in form of the so-called “Artrosskola”; unfortunately, these guidelines are poorly implemented. We aim to obtain a holistic view of OA. By conducting preclinical as well as clinical studies we intend to identify biological, structural and clinical disease markers in order to discover individuals with OA at an earlier stage than what is possible today, as well as to phenotype patients for increased personalized treatment. We ensure the quality of the “Artrosskola” and develop a digital treatment form using a highly innovative and novel Web-based platform.
Research
Osteoarthritis (OA) is the most frequently occurring joint disease and is characterized by a gradual degradation of joint cartilage as well as pain and loss of function. The disease progression is slow; degradation of cartilage occurs for several years prior to symptoms. Radiological changes occur much later in the process. According to current evidence-based guidelines, the primary treatment is physiotherapy and information, preferably in form of the so-called “Artrosskola”; unfortunately, these guidelines are poorly implemented. We aim to obtain a holistic view of OA. By conducting preclinical as well as clinical studies we intend to identify biological, structural and clinical disease markers in order to discover individuals with OA at an earlier stage than what is possible today, as well as to phenotype patients for increased personalized treatment. We ensure the quality of the “Artrosskola” and develop a digital treatment form using a highly innovative and novel Web-based platform.
Subject classification (UKÄ)
- Orthopaedics
Collaborations the last five years
Profiles
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Leif Dahlberg
- Orthopaedics (Lund) - Expert
- Lund OsteoArthritis Division - From molecule to clinical implementation - Project manager
Person
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Andrea Dell'isola
- Lund OsteoArthritis Division - From molecule to clinical implementation
- LU Profile Area: Proactive Ageing - Profile area member
- Lund OsteoArthritis Division - Clinical Epidemiology Unit - Research project participant
Person
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Research output
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The role of metabolic syndrome in osteoarthritis development: Is obesity the key driver?
Andrea, D. I., Karin, M., Johanna, V., Stefan, L. L., Martin, E. & Ali, K., 2026 Mar, In: Osteoarthritis and Cartilage Open. 8, 1, 100739.Research output: Contribution to journal › Article › peer-review
Open Access -
Association between metabolic conditions, physical activity and self-efficacy before and after a first-line exercise and education intervention for osteoarthritis: a longitudinal register study using the SOAD cohort
Recenti, F., Battista, S., Lohmander, S., Vinblad, J., Kiadaliri, A., Abbott, A., Rolfson, O., Englund, M., Testa, M. & Dell’Isola, A., 2025 Sept, In: RMD Open. 11, 3, e005804.Research output: Contribution to journal › Article › peer-review
Open Access -
Association of type 2 diabetes with reoperation, adverse events and mortality after hip and knee replacement: a Swedish register-based study including 109 938 hip and 80 897 knee replacements
Vinblad, J., Bülow, E., Nyberg, F., Eeg-Olofsson, K., W-Dahl, A., Limbäck, G., Englund, M., Abbott, A., Dell’Isola, A. & Rolfson, O., 2025 Sept, In: BMJ Open. 15, 9, e096717.Research output: Contribution to journal › Article › peer-review
Open Access
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Magnetic Resonance Imaging (MRI) Based Biomarkers for Detecting Early Onset of Knee Osteoarthritis Following Injury to the Anterior Cruciate Ligament (ACL) Using Machine Learning-Based Methods
Hassanlou, L. (Researcher), Englund, M. (Supervisor) & Saarakkala, S. (Assistant supervisor)
2023/10/09 → 2027/09/30
Project: Dissertation
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The impact of metabolic health on osteoarthritis, from disease development to joint replacement.
Dell'isola, A. (Researcher), Kiadaliri, A. (Researcher), Turkiewicz, A. (Researcher) & Englund, M. (Researcher)
2023/01/01 → 2027/01/01
Project: Research
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Digital education and physical therapy for people with musculoskeletal pain
Kiadaliri, A. (Researcher), Lohmander, S. (Researcher), Dahlberg, L. (Researcher) & Cronström, A. (Researcher)
Greta and Johan Kock Foundation, Stiftelsen för bistånd åt rörelsehindrade i Skåne
2021/08/02 → …
Project: Research