Research output per year
Research output per year
- 1 - 50 out of 95 results
Search results
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2023
Alteration in Cerebral Metabolism in a Rodent Model of Acute Sub-lethal Cyanide Poisoning
Alomaja, O., Shofer, F. S., Greenwood, J. C., Piel, S., Clayman, C., Mesaros, C., Kao, S. H., Shin, S. S., Ehinger, J. K., Kilbaugh, T. J. & Jang, D. H., 2023, (Accepted/In press) In: Journal of Medical Toxicology.Research output: Contribution to journal › Article › peer-review
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A whole blood approach improves speed and accuracy when measuring mitochondrial respiration in intact avian blood cells
Nord, A., Chamkha, I. & Elmer, E., 2023, In: FASEB Journal. 37, 3, 12 p., e22766.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Downloads (Pure) -
Central venous stenosis after subclavian versus internal jugular dialysis catheter insertion (CITES) in adults in need of a temporary central dialysis catheter: study protocol for a two-arm, parallel-group, non-inferiority randomised controlled trial
Borgquist, O., Naddi, L., Božović, G., Hellberg, M., Annborn, M., Sjövall, F., Adrian, M., Hettinger, E., Sjöberg, P. & Kander, T., 2023 Dec, In: Trials. 24, 1, 327.Research output: Contribution to journal › Article › peer-review
Open Access -
Dose-dependent effects of acetaminophen and ibuprofen on mitochondrial respiration of human platelets
Beţiu, A. M., Lighezan, R., Avram, V. F., Muntean, D. M., Elmér, E. & Petrescu, L., 2023, (E-pub ahead of print) In: Molecular and Cellular Biochemistry.Research output: Contribution to journal › Article › peer-review
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Plasticity of mitochondrial function safeguards phosphorylating respiration during in vitro simulation of rest-phase hypothermia
García-Díaz, C. C., Chamkha, I., Elmer, E. & Nord, A., 2023, In: FASEB Journal. 37, 4, e22854.Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Downloads (Pure) -
Protocolised reduction of non-resuscitation fluids versus usual care in patients with septic shock (REDUSE): a protocol for a multicentre feasibility trial
Lindén, A., Fisher, J., Lilja, G., Olsen, M. H., Sjövall, F., Jungner, M., Spångfors, M., Samuelsson, L., Oras, J., Linder, A., Unden, J., Kander, T., Lipcsey, M., Nielsen, N., Jakobsen, J. C. & Bentzer, P., 2023 Feb 28, In: BMJ Open. 13, 2, p. 1-8 e065392.Research output: Contribution to journal › Article › peer-review
Open Access -
‘Proactive aging’ is a new research approach for a new era
Iwarsson, S., Jönson, H., Deierborg, T., Ehinger, J. K., Hansson, O., Isaksson, H. & Englund, M., 2023 Jun 8, (E-pub ahead of print) In: Nature Aging.Research output: Contribution to journal › Letter › peer-review
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2022
Disease Outcome and Brain Metabolomics of Cyclophilin-D Knockout Mice in Sepsis
Kobayashi, T., Uchino, H., Elmér, E., Ogihara, Y., Fujita, H., Sekine, S., Ishida, Y., Saiki, I., Shibata, S. & Kawachi, A., 2022, In: International Journal of Molecular Sciences. 23, 2, 961.Research output: Contribution to journal › Article › peer-review
Open Access -
Effect of Cyclosporine on Cytokine Production in Elective Coronary Artery Bypass Grafting: A Sub-Analysis of the CiPRICS (Cyclosporine to Protect Renal Function in Cardiac Surgery) Study
Grins, E., Ederoth, P., Bjursten, H., Dardashti, A., Brondén, B., Metzsch, C., Erdling, A., Nozohoor, S., Mokhtari, A., Hansson, M. J., Elmér, E., Algotsson, L., Shrestha, N. M. & Jovinge, S., 2022, In: Journal of Cardiothoracic and Vascular Anesthesia. 36, 7, p. 1985-1994Research output: Contribution to journal › Article › peer-review
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Extended genetic diagnostics for children with profound sensorineural hearing loss by implementing massive parallel sequencing. Diagnostic outcome, family experience and clinical implementation
Elander, J., Ullmark, T., Ehrencrona, H., Jonson, T., Piccinelli, P., Samuelsson, S., Löwgren, K., Falkenius-Schmidt, K., Ehinger, J., Stenfeldt, K. & Värendh, M., 2022 Aug, In: International Journal of Pediatric Otorhinolaryngology. 159, 111218.Research output: Contribution to journal › Article › peer-review
Open Access -
Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences: A multivariate meta-analysis
Junker, A., Wang, J., Gouspillou, G., Ehinger, J. K., Elmér, E., Sjövall, F., Fisher-Wellman, K. H., Neufer, P. D., Molina, A. J. A., Ferrucci, L. & Picard, M., 2022 Feb, In: FASEB Journal. 36, 2, e22146.Research output: Contribution to journal › Article › peer-review
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Mitochondrial Effects of Common Cardiovascular Medications: The Good, the Bad and the Mixed
Bețiu, A. M., Noveanu, L., Hâncu, I. M., Lascu, A., Petrescu, L., Maack, C., Elmér, E. & Muntean, D. M., 2022 Nov, In: International Journal of Molecular Sciences. 23, 21, 13653.Research output: Contribution to journal › Review article › peer-review
Open Access -
Pathogenic mtDNA variants, in particular single large-scale mtDNA deletions, are strongly associated with post-lingual onset sensorineural hearing loss in primary mitochondrial disease
Elander, J., McCormick, E. M., Värendh, M., Stenfeldt, K., Ganetzky, R. D., Goldstein, A., Zolkipli-Cunningham, Z., MacMullen, L. E., Xiao, R., Falk, M. J. & Ehinger, J. K., 2022 Nov, In: Molecular Genetics and Metabolism. 137, 3, p. 230-238 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion
Verma, G., Bowen, A., Gheibi, S., Hamilton, A., Muthukumar, S., Cataldo, L. R., Asplund, O., Esguerra, J., Karagiannopoulos, A., Lyons, C., Cowan, E., Bellodi, C., Prasad, R., Fex, M. & Mulder, H., 2022, In: The Journal of biological chemistry. 298, 3, 101692.Research output: Contribution to journal › Article › peer-review
Open Access -
Succinate prodrugs as treatment for acute metabolic crisis during fluoroacetate intoxication in the rat
Piel, S., Janowska, J. I., Ward, J. L., McManus, M. J., Aronowitz, D. I., Janowski, P. K., Starr, J., Hook, J. N., Hefti, M. M., Clayman, C. L., Elmér, E., Hansson, M. J., Jang, D. H., Karlsson, M., Ehinger, J. K. & Kilbaugh, T. J., 2022, (Accepted/In press) In: Molecular and Cellular Biochemistry.Research output: Contribution to journal › Article › peer-review
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Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning
Piel, S., Janowska, J. I., Ward, J. L., McManus, M. J., Jose, J. S., Starr, J., Sheldon, M., Clayman, C. L., Elmér, E., Hansson, M. J., Jang, D. H., Karlsson, M., Ehinger, J. K. & Kilbaugh, T. J., 2022 Dec, In: Scientific Reports. 12, 1, 20329.Research output: Contribution to journal › Article › peer-review
Open Access -
Synergistic Effects of Sanglifehrin-Based Cyclophilin Inhibitor NV651 with Cisplatin in Hepatocellular Carcinoma
Simón Serrano, S., Tavecchio, M., Mallik, J., Grönberg, A., Elmér, E., Kifagi, C., Gallay, P., Hansson, M. J. & Massoumi, R., 2022 Sept, In: Cancers. 14, 19, 4553.Research output: Contribution to journal › Article › peer-review
Open Access -
The importance of Cyclophilins and Mps1 in cancer
Simon Serrano, S., 2022, Lund: Lund University, Faculty of Medicine. 89 p.Research output: Thesis › Doctoral Thesis (compilation)
Open AccessFile124 Downloads (Pure) -
Towards a treatment for mitochondrial disease: current compounds in clinical development
Åsander Frostner, E., Simon Serrano, S., Chamkha, I., Elmer, E., Donnelly, E. & Hansson, M., 2022 Jun 28, In: Bioenergetics Communications. 2022, 4, p. 1-10Research output: Contribution to journal › Review article › peer-review
Open Access -
Transcriptome and metabolome after porcine hemodynamic-directed CPR compared with standard CPR and sham controls
Senthil, K., Hefti, M. M., Singh, L. N., Morgan, R. W., Mavroudis, C. D., Ko, T., Gaudio, H., Nadkarni, V. M., Ehinger, J., Berg, R. A., Sutton, R. M., McGowan, F. X. & Kilbaugh, T. J., 2022 Jun, In: Resuscitation Plus . 10, 100243.Research output: Contribution to journal › Article › peer-review
Open Access -
Use of the Hollow-Fiber Infection Model to Measure the Effect of Combination Therapy of Septic Shock Exposures of Meropenem and Ciprofloxacin against Intermediate and Resistant Pseudomonas aeruginosa Clinical Isolates
Karabasevic, N., Roberts, J. A., Stronach, L., Naicker, S., Wallis, S. C., Sjövall, F. & Sime, F., 2022 May, In: Antimicrobial Agents and Chemotherapy. 66, 5Research output: Contribution to journal › Article › peer-review
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2021
Alterations in cerebral and cardiac mitochondrial function in a porcine model of acute carbon monoxide poisoning
Jang, D. H., Piel, S., Greenwood, J. C., Kelly, M., Mazandi, V. M., Ranganathan, A., Lin, Y., Starr, J., Hallowell, T., Shofer, F. S., Baker, W. B., Lafontant, A., Andersen, K., Ehinger, J. K. & Kilbaugh, T. J., 2021, In: Clinical Toxicology. 59, 9, p. 801-809 9 p.Research output: Contribution to journal › Article › peer-review
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A new tool to assess Clinical Diversity In Meta-analyses (CDIM) of interventions
Barbateskovic, M., Koster, T. M., Eck, R. J., Maagaard, M., Afshari, A., Blokzijl, F., Cronhjort, M., Dieperink, W., Fabritius, M. L., Feinberg, J., French, C., Gareb, B., Geisler, A., Granholm, A., Hiemstra, B., Hu, R., Imberger, G., Jensen, B. T., Jonsson, A. B., Karam, O., & 25 others, 2021, In: Journal of Clinical Epidemiology. 135, p. 29-41 13 p.Research output: Contribution to journal › Article › peer-review
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Cell‐permeable succinate rescues mitochondrial respiration in cellular models of amiodarone toxicity
Bețiu, A. M., Chamkha, I., Gustafsson, E., Meijer, E., Avram, V. F., Frostner, E. Å., Ehinger, J. K., Petrescu, L., Muntean, D. M. & Elmér, E., 2021 Nov 1, In: International Journal of Molecular Sciences. 22, 21, 11786.Research output: Contribution to journal › Article › peer-review
Open Access -
Cell-Permeable Succinate Rescues Mitochondrial Respiration in Cellular Models of Statin Toxicity
Avram, V. F., Chamkha, I., Åsander-Frostner, E., Ehinger, J. K., Timar, R. Z., Hansson, M. J., Muntean, D. M. & Elmér, E., 2021, In: International Journal of Molecular Sciences. 22, 1, 15 p., 424.Research output: Contribution to journal › Article › peer-review
Open Access -
Emerging cellular-based therapies in carbon monoxide poisoning
Jang, D. H., Piel, S., Greenwood, J. C., Ehinger, J. K. & Kilbaugh, T. J., 2021, In: American Journal of Physiology - Cell Physiology. 321, 2, p. C269-C275Research output: Contribution to journal › Review article › peer-review
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Evaluation of Diffusion Tensor Imaging and Fluid Based Biomarkers in a Large Animal Trial of Cyclosporine in Focal Traumatic Brain Injury
Karlsson, M., Yang, Z., Chawla, S., Delso, N., Pukenas, B., Elmér, E., Hugerth, M., Margulies, S. S., Ehinger, J., Hansson, M. J., Wang, K. K. W. & Kilbaugh, T. J., 2021, In: Journal of Neurotrauma. 38, 13, p. 1870-1878 9 p.Research output: Contribution to journal › Article › peer-review
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Improvement of platelet respiration by cell-permeable succinate in diabetic patients treated with statins
Avram, V. F., Bîna, A. M., Sima, A., Aburel, O. M., Sturza, A., Burlacu, O., Timar, R. Z., Muntean, D. M., Elmér, E. & Cret, O. M., 2021, In: Life. 11, 4, 288.Research output: Contribution to journal › Article › peer-review
Open Access -
Long-term survival after self-expanding metallic stent or stoma decompression as bridge to surgery in acute malignant large bowel obstruction
Axmarker, T., Leffler, M., Lepsenyi, M., Thorlacius, H. & Syk, I., 2021 Mar 5, In: BJS Open. 5, 2Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondrial dysfunction and the metabolism - studies on respiratory chain disorders
Tomasic, N., 2021, Lund: Lund University, Faculty of Medicine. 62 p.Research output: Thesis › Doctoral Thesis (compilation)
Open AccessFile418 Downloads (Pure) -
Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma
Simón Serrano, S., Tavecchio, M., Grönberg, A., Sime, W., Jemaà, M., Moss, S., Gregory, M. A., Gallay, P., Elmér, E., Hansson, M. J. & Massoumi, R., 2021 Jun 18, In: Cancers. 13, 12, 3041.Research output: Contribution to journal › Article › peer-review
Open Access -
Predictors of outcome in children with disorders of mitochondrial metabolism in the pediatric intensive care unit
Ehinger, J. K., Karlsson, M., Sjövall, F., Leffler, M., McCormack, S. E., Kubis, S. E., Åkesson, A., Falk, M. J. & Kilbaugh, T. J., 2021, In: Pediatric Research. 90, 6, p. 1221-1227Research output: Contribution to journal › Article › peer-review
Open Access -
TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration
Russ, K., Teku, G., Bousset, L., Redeker, V., Piel, S., Savchenko, E., Pomeshchik, Y., Savistchenko, J., Stummann, T. C., Azevedo, C., Collin, A., Goldwurm, S., Fog, K., Elmer, E., Vihinen, M., Melki, R. & Roybon, L., 2021, In: Cell Reports. 34, 12, 108895.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study
De Bus, L., Depuydt, P., Steen, J., Dhaese, S., De Smet, K., Tabah, A., Akova, M., Cotta, M. O., De Pascale, G., Dimopoulos, G., Fujitani, S., Garnacho-Montero, J., Leone, M., Lipman, J., Ostermann, M., Paiva, J-A., Schouten, J., Sjövall, F., Timsit, J-F., Roberts, J. A., & 6 others, 2020 Jul, In: Intensive Care Medicine. 46, 7, p. 1404-1417 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose
Piel, S., Chamkha, I., Kozak Dehlin, A., Ehinger, J. K., Sjövall, F., Elmér, E. & Hansson, M. J., 2020, In: PLoS ONE. 15, 4, e0231173.Research output: Contribution to journal › Article › peer-review
Open Access -
Fasting reveals largely intact systemic lipid mobilization mechanisms in respiratory chain complex III deficient mice
Tomašić, N., Kotarsky, H., de Oliveira Figueiredo, R., Hansson, E., Mörgelin, M., Tomašić, I., Kallijärvi, J., Elmér, E., Jauhiainen, M., Eklund, E. A. & Fellman, V., 2020, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 1, 11 p., 165573.Research output: Contribution to journal › Article › peer-review
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Inhibition of mitotic kinase Mps1 promotes cell death in neuroblastoma
Simon Serrano, S., Sime, W., Abassi, Y., Daams, R., Massoumi, R. & Jemaà, M., 2020 Jul 20, In: Scientific Reports. 10, 1, p. 11997Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondrial dysfunction and calcium dysregulation in leigh syndrome induced pluripotent stem cell derived neurons
Galera-Monge, T., Zurita-Díaz, F., Canals, I., Hansen, M. G., Rufián-Vázquez, L., Ehinger, J. K., Elmér, E., Martin, M. A., Garesse, R., Ahlenius, H. & Gallardo, M. E., 2020, In: International Journal of Molecular Sciences. 21, 9, 3191.Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug
Janowska, J. I., Piel, S., Saliba, N., Kim, C. D., Jang, D. H., Karlsson, M., Kilbaugh, T. J. & Ehinger, J. K., 2020, In: Toxicology in Vitro. 65, 104794.Research output: Contribution to journal › Article › peer-review
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Preferential Killing of Tetraploid Colon Cancer Cells by Targeting the Mitotic Kinase PLK1
Jemaà, M., Kifagi, C., Serrano, S. S. & Massoumi, R., 2020 Apr 8, In: Cellular Physiology and Biochemistry. 54, 2, p. 303-320Research output: Contribution to journal › Article › peer-review
Open Access -
Urban PM2.5 Induces Cellular Toxicity, Hormone Dysregulation, Oxidative Damage, Inflammation, and Mitochondrial Interference in the HRT8 Trophoblast Cell Line
Nääv, Å., Erlandsson, L., Isaxon, C., Åsander Frostner, E., Ehinger, J., Elmer, E., Sporre, M., Krais, A., Strandberg, B., Lundh, T., Malmqvist, E. & Hansson, S., 2020 Mar 12, In: Frontiers in Endocrinology. 11, 75.Research output: Contribution to journal › Article › peer-review
Open Access -
α1-Microglobulin (A1M) Protects Human Proximal Tubule Epithelial Cells from Heme-Induced Damage In Vitro
Kristiansson, A., Davidsson, S., Johansson, M. E., Piel, S., Elmér, E., Hansson, M. J., Åkerström, B. & Gram, M., 2020, In: International Journal of Molecular Sciences. 21, 16, 16 p., 5825.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene
Chumarina, M., Russ, K., Azevedo, C., Heuer, A., Pihl, M., Collin, A., Frostner, E. Å., Elmer, E., Hyttel, P., Cappelletti, G., Zini, M., Goldwurm, S. & Roybon, L., 2019 Dec 16, In: Acta Neuropathologica Communications. 7, 1, 208.Research output: Contribution to journal › Article › peer-review
Open Access -
Copenhagen Head Injury Ciclosporin Study: A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients
Kelsen, J., Karlsson, M., Hansson, M. J., Yang, Z., Fischer, W., Hugerth, M., Nordström, C. H., Åstrand, R., Keep, M. F., Kilbaugh, T., Wang, K. K. W., Møller, K., Juhler, M. & Elmér, E., 2019, In: Journal of Neurotrauma. 36, 23, p. 3253-3263 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cyclophilin Inhibitor NV556 Reduces Fibrosis and Hepatocellular Carcinoma Development in Mice With Non-Alcoholic Steatohepatitis
Kuo, J., Serrano, S. S., Grönberg, A., Massoumi, R., Hansson, M. J. & Gallay, P., 2019, In: Frontiers in Pharmacology. 10, 1129.Research output: Contribution to journal › Article › peer-review
Open Access -
Defining optimal dosing of ciprofloxacin in patients with septic shock
Roberts, J. A., Alobaid, A. S., Wallis, S. C., Perner, A., Lipman, J. & Sjövall, F., 2019, In: The Journal of antimicrobial chemotherapy. 74, 6, p. 1662-1669 8 p.Research output: Contribution to journal › Article › peer-review
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Evaluation of NV556, a Novel Cyclophilin Inhibitor, as a Potential Antifibrotic Compound for Liver Fibrosis
Simón Serrano, S., Grönberg, A., Longato, L., Rombouts, K., Kuo, J., Gregory, M., Moss, S., Elmér, E., Mazza, G., Gallay, P., Pinzani, M., Hansson, M. J. & Massoumi, R., 2019 Nov 8, In: Cells. 8, 11Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondrial respiratory states and rates
Gnaiger, E., Åsander Frostner, E., Ehinger, J., Elmer, E., Piel, S., Zvejniece, L. & MitoEAGLE Task Group, 2019 Apr 24, MitoFit Preprints.Research output: Other contribution › Miscellaneous › Research
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Neuroprotective Effects of Cyclosporine in a Porcine Pre-Clinical Trial of Focal Traumatic Brain Injury
Karlsson, M., Pukenas, B., Chawla, S., Ehinger, J. K., Plyler, R., Stolow, M., Gabello, M., Hugerth, M., Elmér, E., Hansson, M. J., Margulies, S. & Kilbaugh, T., 2019, In: Journal of Neurotrauma. 36, 1, p. 14-24 11 p.Research output: Contribution to journal › Article › peer-review
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Update in antibiotic therapy in intensive care unit: report from the 2019 Nîmes International Symposium
Leone, M., Roberts, J. A., Bassetti, M., Bouglé, A., Lavigne, J. P., Legrand, M., Neely, M., Paiva, J. A., Payen, D., Rello, J., Roger, C., Sjövall, F. & Jung, B., 2019, In: Anaesthesia Critical Care & Pain Medicine. 38, 6, p. 647-656Research output: Contribution to journal › Review article › peer-review