Research output per year
Research output per year
- 1 - 50 out of 68 results
Search results
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2022
Disease Outcome and Brain Metabolomics of Cyclophilin-D Knockout Mice in Sepsis
Kobayashi, T., Uchino, H., Elmér, E., Ogihara, Y., Fujita, H., Sekine, S., Ishida, Y., Saiki, I., Shibata, S. & Kawachi, A., 2022, In: International Journal of Molecular Sciences. 23, 2, 961.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (SciVal) -
Effect of Cyclosporine on Cytokine Production in Elective Coronary Artery Bypass Grafting: A Sub-Analysis of the CiPRICS (Cyclosporine to Protect Renal Function in Cardiac Surgery) Study
Grins, E., Ederoth, P., Bjursten, H., Dardashti, A., Brondén, B., Metzsch, C., Erdling, A., Nozohoor, S., Mokhtari, A., Hansson, M. J., Elmér, E., Algotsson, L., Shrestha, N. M. & Jovinge, S., 2022, In: Journal of Cardiothoracic and Vascular Anesthesia. 36, 7, p. 1985-1994Research output: Contribution to journal › Article › peer-review
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Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences: A multivariate meta-analysis
Junker, A., Wang, J., Gouspillou, G., Ehinger, J. K., Elmér, E., Sjövall, F., Fisher-Wellman, K. H., Neufer, P. D., Molina, A. J. A., Ferrucci, L. & Picard, M., 2022 Feb, In: FASEB Journal. 36, 2, e22146.Research output: Contribution to journal › Article › peer-review
1 Citation (SciVal) -
Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion
Verma, G., Bowen, A., Gheibi, S., Hamilton, A., Muthukumar, S., Cataldo, L. R., Asplund, O., Esguerra, J., Karagiannopoulos, A., Lyons, C., Cowan, E., Bellodi, C., Prasad, R., Fex, M. & Mulder, H., 2022 Feb 8, (E-pub ahead of print) In: The Journal of biological chemistry. p. 101692Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Alterations in cerebral and cardiac mitochondrial function in a porcine model of acute carbon monoxide poisoning
Jang, D. H., Piel, S., Greenwood, J. C., Kelly, M., Mazandi, V. M., Ranganathan, A., Lin, Y., Starr, J., Hallowell, T., Shofer, F. S., Baker, W. B., Lafontant, A., Andersen, K., Ehinger, J. K. & Kilbaugh, T. J., 2021, In: Clinical Toxicology. 59, 9, p. 801-809 9 p.Research output: Contribution to journal › Article › peer-review
2 Citations (SciVal) -
A new tool to assess Clinical Diversity In Meta-analyses (CDIM) of interventions
Barbateskovic, M., Koster, T. M., Eck, R. J., Maagaard, M., Afshari, A., Blokzijl, F., Cronhjort, M., Dieperink, W., Fabritius, M. L., Feinberg, J., French, C., Gareb, B., Geisler, A., Granholm, A., Hiemstra, B., Hu, R., Imberger, G., Jensen, B. T., Jonsson, A. B., Karam, O. & 25 others, , 2021, In: Journal of Clinical Epidemiology. 135, p. 29-41 13 p.Research output: Contribution to journal › Article › peer-review
13 Citations (SciVal) -
Cell‐permeable succinate rescues mitochondrial respiration in cellular models of amiodarone toxicity
Bețiu, A. M., Chamkha, I., Gustafsson, E., Meijer, E., Avram, V. F., Frostner, E. Å., Ehinger, J. K., Petrescu, L., Muntean, D. M. & Elmér, E., 2021 Nov 1, In: International Journal of Molecular Sciences. 22, 21, 11786.Research output: Contribution to journal › Article › peer-review
Open Access -
Cell-Permeable Succinate Rescues Mitochondrial Respiration in Cellular Models of Statin Toxicity
Avram, V. F., Chamkha, I., Åsander-Frostner, E., Ehinger, J. K., Timar, R. Z., Hansson, M. J., Muntean, D. M. & Elmér, E., 2021, In: International Journal of Molecular Sciences. 22, 1, 15 p., 424.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (SciVal) -
Evaluation of Diffusion Tensor Imaging and Fluid Based Biomarkers in a Large Animal Trial of Cyclosporine in Focal Traumatic Brain Injury
Karlsson, M., Yang, Z., Chawla, S., Delso, N., Pukenas, B., Elmér, E., Hugerth, M., Margulies, S. S., Ehinger, J., Hansson, M. J., Wang, K. K. W. & Kilbaugh, T. J., 2021, In: Journal of Neurotrauma. 38, 13, p. 1870-1878 9 p.Research output: Contribution to journal › Article › peer-review
1 Citation (SciVal) -
Improvement of platelet respiration by cell-permeable succinate in diabetic patients treated with statins
Avram, V. F., Bîna, A. M., Sima, A., Aburel, O. M., Sturza, A., Burlacu, O., Timar, R. Z., Muntean, D. M., Elmér, E. & Cret, O. M., 2021, In: Life. 11, 4, 288.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (SciVal) -
Long-term survival after self-expanding metallic stent or stoma decompression as bridge to surgery in acute malignant large bowel obstruction
Axmarker, T., Leffler, M., Lepsenyi, M., Thorlacius, H. & Syk, I., 2021 Mar 5, In: BJS Open. 5, 2Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (SciVal) -
Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma
Simón Serrano, S., Tavecchio, M., Grönberg, A., Sime, W., Jemaà, M., Moss, S., Gregory, M. A., Gallay, P., Elmér, E., Hansson, M. J. & Massoumi, R., 2021 Jun 18, In: Cancers. 13, 12, 3041.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (SciVal) -
Predictors of outcome in children with disorders of mitochondrial metabolism in the pediatric intensive care unit
Ehinger, J. K., Karlsson, M., Sjövall, F., Leffler, M., McCormack, S. E., Kubis, S. E., Åkesson, A., Falk, M. J. & Kilbaugh, T. J., 2021, In: Pediatric Research. 90, 6, p. 1221-1227Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (SciVal) -
TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration
Russ, K., Teku, G., Bousset, L., Redeker, V., Piel, S., Savchenko, E., Pomeshchik, Y., Savistchenko, J., Stummann, T. C., Azevedo, C., Collin, A., Goldwurm, S., Fog, K., Elmer, E., Vihinen, M., Melki, R. & Roybon, L., 2021, In: Cell Reports. 34, 12, 108895.Research output: Contribution to journal › Article › peer-review
Open Access15 Citations (SciVal) -
2020
Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study
De Bus, L., Depuydt, P., Steen, J., Dhaese, S., De Smet, K., Tabah, A., Akova, M., Cotta, M. O., De Pascale, G., Dimopoulos, G., Fujitani, S., Garnacho-Montero, J., Leone, M., Lipman, J., Ostermann, M., Paiva, J-A., Schouten, J., Sjövall, F., Timsit, J-F., Roberts, J. A. & 6 others, , 2020 Jul, In: Intensive Care Medicine. 46, 7, p. 1404-1417 14 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (SciVal) -
Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose
Piel, S., Chamkha, I., Kozak Dehlin, A., Ehinger, J. K., Sjövall, F., Elmér, E. & Hansson, M. J., 2020, In: PLoS ONE. 15, 4, e0231173.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (SciVal) -
Fasting reveals largely intact systemic lipid mobilization mechanisms in respiratory chain complex III deficient mice
Tomašić, N., Kotarsky, H., de Oliveira Figueiredo, R., Hansson, E., Mörgelin, M., Tomašić, I., Kallijärvi, J., Elmér, E., Jauhiainen, M., Eklund, E. A. & Fellman, V., 2020, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 1, 11 p., 165573.Research output: Contribution to journal › Article › peer-review
3 Citations (SciVal) -
Inhibition of mitotic kinase Mps1 promotes cell death in neuroblastoma
Simon Serrano, S., Sime, W., Abassi, Y., Daams, R., Massoumi, R. & Jemaà, M., 2020 Jul 20, In: Scientific Reports. 10, 1, p. 11997Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (SciVal) -
Mitochondrial dysfunction and calcium dysregulation in leigh syndrome induced pluripotent stem cell derived neurons
Galera-Monge, T., Zurita-Díaz, F., Canals, I., Hansen, M. G., Rufián-Vázquez, L., Ehinger, J. K., Elmér, E., Martin, M. A., Garesse, R., Ahlenius, H. & Gallardo, M. E., 2020, In: International Journal of Molecular Sciences. 21, 9, 3191.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (SciVal) -
Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug
Janowska, J. I., Piel, S., Saliba, N., Kim, C. D., Jang, D. H., Karlsson, M., Kilbaugh, T. J. & Ehinger, J. K., 2020, In: Toxicology in Vitro. 65, 104794.Research output: Contribution to journal › Article › peer-review
5 Citations (SciVal) -
Preferential Killing of Tetraploid Colon Cancer Cells by Targeting the Mitotic Kinase PLK1
Jemaà, M., Kifagi, C., Serrano, S. S. & Massoumi, R., 2020 Apr 8, In: Cellular Physiology and Biochemistry. 54, 2, p. 303-320Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (SciVal) -
Urban PM2.5 Induces Cellular Toxicity, Hormone Dysregulation, Oxidative Damage, Inflammation, and Mitochondrial Interference in the HRT8 Trophoblast Cell Line
Nääv, Å., Erlandsson, L., Isaxon, C., Åsander Frostner, E., Ehinger, J., Elmer, E., Sporre, M., Krais, A., Strandberg, B., Lundh, T., Malmqvist, E. & Hansson, S., 2020 Mar 12, In: Frontiers in Endocrinology. 11, 75.Research output: Contribution to journal › Article › peer-review
Open Access30 Citations (SciVal) -
α1-Microglobulin (A1M) Protects Human Proximal Tubule Epithelial Cells from Heme-Induced Damage In Vitro
Kristiansson, A., Davidsson, S., Johansson, M. E., Piel, S., Elmér, E., Hansson, M. J., Åkerström, B. & Gram, M., 2020, In: International Journal of Molecular Sciences. 21, 16, 16 p., 5825.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (SciVal) -
2019
Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene
Chumarina, M., Russ, K., Azevedo, C., Heuer, A., Pihl, M., Collin, A., Frostner, E. Å., Elmer, E., Hyttel, P., Cappelletti, G., Zini, M., Goldwurm, S. & Roybon, L., 2019 Dec 16, In: Acta Neuropathologica Communications. 7, 1, 208.Research output: Contribution to journal › Article › peer-review
Open Access14 Citations (SciVal) -
Copenhagen Head Injury Ciclosporin Study: A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients
Kelsen, J., Karlsson, M., Hansson, M. J., Yang, Z., Fischer, W., Hugerth, M., Nordström, C. H., Åstrand, R., Keep, M. F., Kilbaugh, T., Wang, K. K. W., Møller, K., Juhler, M. & Elmér, E., 2019, In: Journal of Neurotrauma. 36, 23, p. 3253-3263 11 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Citations (SciVal) -
Cyclophilin Inhibitor NV556 Reduces Fibrosis and Hepatocellular Carcinoma Development in Mice With Non-Alcoholic Steatohepatitis
Kuo, J., Serrano, S. S., Grönberg, A., Massoumi, R., Hansson, M. J. & Gallay, P., 2019, In: Frontiers in Pharmacology. 10, 1129.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (SciVal) -
Defining optimal dosing of ciprofloxacin in patients with septic shock
Roberts, J. A., Alobaid, A. S., Wallis, S. C., Perner, A., Lipman, J. & Sjövall, F., 2019, In: The Journal of antimicrobial chemotherapy. 74, 6, p. 1662-1669 8 p.Research output: Contribution to journal › Article › peer-review
12 Citations (SciVal) -
Evaluation of NV556, a Novel Cyclophilin Inhibitor, as a Potential Antifibrotic Compound for Liver Fibrosis
Simón Serrano, S., Grönberg, A., Longato, L., Rombouts, K., Kuo, J., Gregory, M., Moss, S., Elmér, E., Mazza, G., Gallay, P., Pinzani, M., Hansson, M. J. & Massoumi, R., 2019 Nov 8, In: Cells. 8, 11Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (SciVal) -
Neuroprotective Effects of Cyclosporine in a Porcine Pre-Clinical Trial of Focal Traumatic Brain Injury
Karlsson, M., Pukenas, B., Chawla, S., Ehinger, J. K., Plyler, R., Stolow, M., Gabello, M., Hugerth, M., Elmér, E., Hansson, M. J., Margulies, S. & Kilbaugh, T., 2019, In: Journal of Neurotrauma. 36, 1, p. 14-24 11 p.Research output: Contribution to journal › Article › peer-review
18 Citations (SciVal) -
2018
Atherosclerosis, Hypertension, and Diabetes in Alzheimer's Disease, Vascular Dementia, and Mixed Dementia: Prevalence and Presentation
Javanshiri, K., Waldö, M. L., Friberg, N., Sjövall, F., Wickerström, K., Haglund, M. & Englund, E., 2018, In: Journal of Alzheimer's Disease. 65, 4, p. 1247-1258 12 p.Research output: Contribution to journal › Article › peer-review
21 Citations (SciVal) -
Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production
Piel, S., Ehinger, J. K., Chamkha, I., Frostner, E. Å., Sjövall, F., Elmér, E. & Hansson, M. J., 2018 Aug 1, In: Intensive Care Medicine Experimental. 6, 1, 22.Research output: Contribution to journal › Article › peer-review
Open Access -
Cyclosporine before Coronary Artery Bypass Grafting Does Not Prevent Postoperative Decreases in Renal Function: A Randomized Clinical Trial
Ederoth, P., Dardashti, A., Grins, E., Brondén, B., Metzsch, C., Erdling, A., Nozohoor, S., Mokhtari, A., Hansson, M. J., Elmér, E., Algotsson, L., Jovinge, S. & Bjursten, H., 2018, In: Anesthesiology. 128, 4, p. 710-717Research output: Contribution to journal › Article › peer-review
4 Citations (SciVal) -
Do GSTM1 and GSTT1 polymorphisms influence the risk of developing mitochondrial diseases in a Tunisian population?
Ghorbel, R., Ben Salah, G., Ghorbel, R., Ben Mahmoud, A., Chamkha, I., Mkaouar-Rebai, E., Ammar-Keskes, L. & Fakhfakh, F., 2018 Feb, In: Environmental Science and Pollution Research. 25, 6, p. 5779-5787Research output: Contribution to journal › Article › peer-review
2 Citations (SciVal) -
Intensive care doctors’ preferences for arterial oxygen tension levels in mechanically ventilated patients
Schjørring, O. L., Toft-Petersen, A. P., Kusk, K. H., Mouncey, P., Sørensen, E. E., Berezowicz, P., Bestle, M. H., Bülow, H. H., Bundgaard, H., Christensen, S., Iversen, S. A., Kirkeby-Garstad, I., Krarup, K. B., Kruse, M., Laake, J. H., Liboriussen, L., Læbel, R. L., Okkonen, M., Poulsen, L. M., Russell, L. & 8 others, , 2018, In: Acta Anaesthesiologica Scandinavica. 62, 10, p. 1443-1451 9 p.Research output: Contribution to journal › Article › peer-review
10 Citations (SciVal) -
Maximally effective dosing regimens of meropenem in patients with septic shock
Sjövall, F., Alobaid, A. S., Wallis, S. C., Perner, A., Lipman, J. & Roberts, J. A., 2018 Jan 1, In: Journal of Antimicrobial Chemotherapy. 73, 1, p. 191-198 8 p., dkx330.Research output: Contribution to journal › Article › peer-review
29 Citations (SciVal) -
Untargeted antifungal therapy in adult patients with complicated intra-abdominal infection: A systematic review
Petersen, M. W., Perner, A., Ravn, F., Sjövall, F. & Møller, M. H., 2018 Jan, In: Acta Anaesthesiologica Scandinavica. 62, 1, p. 6-18Research output: Contribution to journal › Article › peer-review
2 Citations (SciVal) -
2017
Co segregation of the m.1555A>G mutation in the MT-RNR1 gene and mutations in MT-ATP6 gene in a family with dilated mitochondrial cardiomyopathy and hearing loss: A whole mitochondrial genome screening
Alila-Fersi, O., Chamkha, I., Majdoub, I., Gargouri, L., Mkaouar-Rebai, E., Tabebi, M., Tlili, A., Keskes, L., Mahfoudh, A. & Fakhfakh, F., 2017 Feb 26, In: Biochemical and Biophysical Research Communications. 484, 1, p. 71-78 8 p.Research output: Contribution to journal › Article › peer-review
7 Citations (SciVal) -
Hospitalizations for mitochondrial disease across the lifespan in the U.S
McCormack, S. E., Xiao, R., Kilbaugh, T. J., Karlsson, M., Ganetzky, R. D., Cunningham, Z. Z., Goldstein, A., Falk, M. J. & Damrauer, S. M., 2017, In: Molecular Genetics and Metabolism. 121, 2, p. 119-126Research output: Contribution to journal › Article › peer-review
10 Citations (SciVal) -
Oxygen consumption in platelets as an adjunct diagnostic method for pediatric mitochondrial disease
Westerlund, E., Marelsson, S. E., Ehinger, J. K., Sjövall, F., Morota, S., Åsander Frostner, E., Oldfors, A., Darin, N., Lundgren, J., Hansson, M. J., Fellman, V. & Elmér, E., 2017 Nov 15, In: Pediatric Research. 83, p. 455–465Research output: Contribution to journal › Article › peer-review
2 Citations (SciVal) -
Respiratory chain complex III deficiency due to mutated BCS1L: A novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model
Tegelberg, S., Tomašić, N., Kallijärvi, J., Purhonen, J., Elmér, E., Lindberg, E., Nord, D. G., Soller, M., Lesko, N., Wedell, A., Bruhn, H., Freyer, C., Stranneheim, H., Wibom, R., Nennesmo, I., Wredenberg, A., Eklund, E. A. & Fellman, V., 2017 Apr 20, In: Orphanet Journal of Rare Diseases. 12, 1, 73.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (SciVal) -
2016
Cell-permeable succinate prodrugs bypass mitochondrial complex i deficiency
Ehinger, J. K., Piel, S., Ford, R., Karlsson, M., Sjövall, F., Frostner, E. Å., Morota, S., Taylor, R. W., Turnbull, D. M., Cornell, C., Moss, S. J., Metzsch, C., Hansson, M. J., Fliri, H. & Elmér, E., 2016 Aug 9, In: Nature Communications. 7, 12317.Research output: Contribution to journal › Article › peer-review
Open Access76 Citations (SciVal) -
Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction – An in vivo large animal model
Karlsson, M., Ehinger, J. K., Piel, S., Sjövall, F., Henriksnäs, J., Höglund, U., Hansson, M. J. & Elmér, E., 2016 Nov 1, In: Mitochondrion. 31, p. 56-62 7 p.Research output: Contribution to journal › Article › peer-review
8 Citations (SciVal) -
Ciclosporin to Protect Renal function In Cardiac Surgery (CiPRICS): A study protocol for a double-blind, randomised, placebo-controlled, proof-of-concept study
Ederoth, P., Grins, E., Dardashti, A., Brondén, B., Metzsch, C., Erdling, A., Nozohoor, S., Mokhtari, A., Hansson, M. J., Elmér, E., Algotsson, L., Jovinge, S. & Bjursten, H., 2016 Dec 1, In: BMJ Open. 6, 12, bmjopen-2016-012299.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (SciVal) -
Diverse and Tissue Specific Mitochondrial Respiratory Response in A Mouse Model of Sepsis-Induced Multiple Organ Failure.
Karlsson, M., Hara, N., Morata, S., Sjövall, F., Kilbaugh, T., Hansson, M., Uchino, H. & Elmer, E., 2016, In: Shock. 45, 4, p. 404-410Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (SciVal)196 Downloads (Pure) -
Mitochondrial Respiratory Function in Peripheral Blood Cells from Huntington's Disease Patients
EHINGER, JOHANNES., Morota, S., Hansson, M., Paul-Visse, G. & Elmer, E., 2016 Sep, In: Movement Disorders Clinical Practice. 3, 5, p. 472–482Research output: Contribution to journal › Article › peer-review
14 Citations (SciVal) -
White adipose tissue browning in the R6/2 mouse model of Huntington's disease
McCourt, A. C., Jakobsson, L., Larsson, S., Holm, C., Piel, S., Elmér, E. & Björkqvist, M., 2016 Aug 1, In: PLoS ONE. 11, 8, e0159870.Research output: Contribution to journal › Article › peer-review
Open Access15 Citations (SciVal) -
2015
Cyclosporine before PCI in Patients with Acute Myocardial Infarction
Cung, T. -T., Morel, O., Cayla, G., Rioufol, G., Garcia-Dorado, D., Angoulvant, D., Bonnefoy-Cudraz, E., Guerin, P., Elbaz, M., Delarche, N., Coste, P., Vanzetto, G., Metge, M., Aupetit, J. -F., Jouve, B., Motreff, P., Tron, C., Labeque, J. -N., Steg, P. G., Cottin, Y. & 33 others, , 2015, In: New England Journal of Medicine. 373, 11, p. 1021-1031Research output: Contribution to journal › Article › peer-review
435 Citations (SciVal) -
Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain.
Kilbaugh, T. J., Karlsson, M., Byro, M., Bebee, A., Ralston, J., Sullivan, S., Duhaime, A-C., Hansson, M., Elmer, E. & Margulies, S. S., 2015, In: Experimental Neurology. 271, p. 136-144Research output: Contribution to journal › Article › peer-review
32 Citations (SciVal) -
Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients.
Ehinger, J., Morota, S., Hansson, M., Paul-Visse, G. & Elmer, E., 2015, In: Journal of Neurology. 262, 6, p. 1493-1503Research output: Contribution to journal › Article › peer-review
26 Citations (SciVal) -
Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury.
Kilbaugh, T. J., Karlsson, M., Duhaime, A-C., Hansson, M., Elmer, E. & Margulies, S. S., 2015, In: Mitochondrion.Research output: Contribution to journal › Article › peer-review
23 Citations (SciVal)