Research output per year
Research output per year
Unit profile
Description
Emma Hammarlund is Research Group Leader for this research group
What it takes to form multicellularity remains poorly understood – whether it’s in the shape of animals or tumors. We discuss whether the key components behind the rise of multicellularity are developmental, environmental, or ecological. To explore these key components, and their interaction, will advance our view on our origins. While the rise of animals is commonly studied with clues from Earth history (geology) and their development (biology), tumor biology can add unique real-time insight to the dynamics at a successful rise of ‘ugly’ multicellularity. And vice versa, insights from organismal evolution over geological time can provide a frame of reference to how we interrogate tumor evolution.
Research
In a transdisciplinary effort, we utilize both geobiology and tumor biology to explore the evolutionary roots to animal health and disease. One focus is the role that biological innovations like the cellular hypoxic response machineries have played for the rise of complex multicellularity. Another focus is the shared programs that unicellular organisms and single cancer cells utilize for metabolism, motility, and mediation of toxicity.
Subject classification (UKÄ)
- Multidisciplinary Geosciences
- Cell and Molecular Biology
- Cancer and Oncology
- Evolutionary Biology
- Developmental Biology
Free keywords
- Developmental evolutionary biology
- geobiology
- differentiation
- stemness
- HIF
- animal evolution
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Mikaela Ahlin
- Molecular Evolution - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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Etienne Baratchart
- Molecular Evolution - Postdoctoral fellow
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Member of Strategic Research Area
Person
Research output
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Benthic diel oxygen variability and stress as potential drivers for animal diversification in the Neoproterozoic-Palaeozoic
Hammarlund, E. U., Bukkuri, A., Norling, M. D., Islam, M., Posth, N. R., Baratchart, E., Carroll, C., Amend, S. R., Gatenby, R. A., Pienta, K. J., Brown, J. S., Peters, S. E. & Hancke, K., 2025 Dec, In: Nature Communications. 16, 1, 2223.Research output: Contribution to journal › Article › peer-review
Open Access -
The impact of a high fat diet and platelet activation on pre-metastatic niche formation
Hergueta-Redondo, M., Sánchez-Redondo, S., Hurtado, B., Santos, V., Pérez-Martínez, M., Ximénez- Embún, P., McDowell, S. A. C., Mazariegos, M. S., Mata, G., Torres-Ruiz, R., Rodríguez-Perales, S., Martínez, L., Graña-Castro, O., Megias, D., Quail, D., Quintela-Fandino, M. & Peinado, H., 2025 Dec, In: Nature Communications. 16, 1, 2897.Research output: Contribution to journal › Article › peer-review
Open Access -
MicroRNA-379 Modulates Prostate-Specific Antigen Expression Through Targeting the Androgen Receptor in Prostate Cancer
Cassidy, J. R., Persson, M., Voss, G., Underbjerg, K. R., Ivkovic, T. C., Bjartell, A., Edsjö, A., Lilja, H. & Ceder, Y., 2025 Oct 7, In: Cancers. 17, 19, p. 1-13 3245.Research output: Contribution to journal › Article › peer-review
Open Access
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Interactions between A-to-I RNA editing and (micro)environmental oxygen across animals
Voss, G. (PI)
2025/11/01 → 2027/10/31
Project: Research
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Isotopic Fingerprinting of Hair to Detect the Presence of Cancer
Hammarlund, E. (PI)
2025/07/01 → 2026/07/31
Project: Research
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Characterizing the breast cancer specific elemental profile and its power to monitor and predict nascent invasive tumor growth
Azemovic, L. (Research student), Hammarlund, E. (Supervisor) & Niméus, E. (Supervisor)
2025/03/01 → 2033/03/01
Project: Dissertation
Activities
- 1 Organisation of workshop/ seminar/ course
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UniStem Day 2024: Dissemination and outreach of stem cell science
Ottosson, D. (Organiser), Magnusson, M. (Organiser), Kidnapillai, S. (Organiser), Ahlenius, H. (Organiser), Luis, A. B. (Organiser), Martinez Curiel, R. (Organiser), Laurin, K. (Organiser), Martos Salvo, P. (Organiser), Das, M. (Contributor), Wendler, M. (Contributor), Sivani, B. M. (Contributor), Ramos Passarello, G. (Contributor), Sozzi, E. (Contributor), García Garrote, M. (Contributor), Harrison Umeano, C. (Contributor), Okeke, U. C. (Contributor), Horvath, V. (Contributor), Garza, R. (Contributor), Adami, A. (Contributor), Castilla-Vallmanya, L. (Contributor), Gerdes, P. (Contributor), Pandiloski, N. (Contributor), Jin, Q. (Contributor), de Guidi, C. (Contributor), Palma Tortosa, S. (Contributor), Fritze, J. (Contributor), Jansson, L. I. (Contributor), Robles Rodriguez, L. (Contributor), Pracucci, E. (Contributor), Shen, Y.-P. (Contributor), Trovato, F. (Contributor), Tampé, J. (Contributor), Thakore, R. (Contributor), Stamouli, C.-A. (Contributor), Pinto dos Santos Vaz, C. (Contributor), Aretio, C. (Contributor), Piochon, C. (Contributor), Cepeda-Prado, E. (Contributor), de Jongh, M.-M. (Contributor), Tsalkitzidou, M. (Contributor), Bonsberger, J. (Contributor), Douse, C. (Contributor), Dorazehi, F. (Contributor), Koutounidou, S. (Contributor), Jarl, U. (Contributor), Corsi, S. (Contributor), Bruzelius, A. (Contributor), Mattsson, B. (Contributor), Hammarberg, A. (Contributor), Habekost, M. (Contributor), Prabhala, P. (Contributor), Bremborg, T. (Contributor), Nair, M. S. (Contributor), Burdeyron, P. (Contributor), Mazariegos, M. (Contributor), Björklund, M. (Contributor), Hidalgo, I. (Contributor), Hägg, A. (Invited speaker), Hammarlund, E. (Invited speaker), Mohlin, S. (Invited speaker) & Oesterle, M. (Contributor)
2024 Mar 22Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
Prizes and distinction
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Childhood Cancer Researcher of the Year
Hagerling, C. (Recipient), 2024
Prize: Prize (including medals and awards)