Research output per year
Research output per year
Unit profile
Research
We are interested in how gene expression is regulated in the brain and how this process influence neurodegenerative diseases, psychiatric disorders and brain tumors. Our current focus is to study the role of epigenetic mechanisms and microRNAs. Our technical expertise include lentiviral vectors, transgenic mice and stem cells cultures.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Anita Adami
- Molecular Neurogenetics - Doctoral student
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Member of Strategic Research Area
- MultiPark: Multidisciplinary research on neurodegenerative diseases - Member of Strategic Research Area
- Infect@LU - Affiliated researcher
Person
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Sara Bermudez
- MultiPark: Multidisciplinary research on neurodegenerative diseases - Member of Strategic Research Area
- Neurodegenerative research - Visiting research fellow
- Molecular Neurogenetics - Postdoc
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Member of Strategic Research Area
- Infect@LU - Affiliated researcher
Person
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Laura Castilla Vallmanya
- Molecular Neurogenetics - Project manager
- MultiPark: Multidisciplinary research on neurodegenerative diseases - Member of Strategic Research Area
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Member of Strategic Research Area
Person
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Protocol for efficient CRISPRi-mediated silencing of retrotransposons in human pluripotent stem cells
Adami, A., Garza, R., Dorazehi, F., Douse, C. H. & Jakobsson, J., 2026 Mar 20, In: STAR Protocols. 7, 1, 104398.Research output: Contribution to journal › Article › peer-review
Open Access -
Loss of SETDB1-mediated H3K9me3 in human neural progenitor cells leads to transcriptional activation of L1 retrotransposons
Karlsson, O., Pandiloski, N., Horvath, V., Adami, A., Garza, R., Johansson, P. A., Johansson, J. G., Douse, C. H. & Jakobsson, J., 2026 Feb, In: Nucleic Acids Research. 54, 4, gkag100.Research output: Contribution to journal › Article › peer-review
Open Access -
Symptomatic SARS-CoV-2 breakthrough infections broaden the repertoire of Spike-reactive CD4 T cells
Johansson, E., Lee, Y., Fajardo-Rosas, V., Abawi, A., Premlal, A. L. R., Frazier, A., Greenbaum, J. A., Vijayanand, P., Antunes, R. D. S. & Sette, A., 2026 Jan 14, In: mBio. 17, 1, p. 1-18 18 p.Research output: Contribution to journal › Article › peer-review
Open Access
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Dynamic regulatory role of Transposable Elements through human ageing and Parkinson's Disease
Garza, R. (PI)
The Michael J. Fox Foundation for Parkinson’s Research
2026/04/01 → 2028/03/31
Project: Research
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Aging and the Heterogeneity of Parkinson's disease - The role of heterochromatin erosion
Jakobsson, J. (PI)
The Michael J. Fox Foundation for Parkinson’s Research
2026/04/01 → 2029/03/31
Project: Research
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Unveiling the function and regulation of tumour-associated histone mutations to develop new cancer treatments
Saredi, G. (PI)
2025/07/01 → 2028/06/30
Project: Research
Activities
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LU-UCL Collaborative Initiative on Neurodegeneration and Repeats
Castilla-Vallmanya, L. (Organiser), Douse, C. (Organiser), Spotorno, N. (Organiser), Tosoni, G. (Contributor), Saredi, G. (Contributor), Santillo, A. (Contributor), Byrne, L. (Organiser), Marchi, P. (Contributor), Cammack, A. (Contributor), Hensman Moss, D. (Contributor), Chen, Z. (Contributor) & Tucci, A. (Contributor)
2026 Mar 12Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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Neuroscience Day 2025
Garwicz, M. (Member of programme committee), Kokaia, M. (Member of programme committee), Ekdahl Clementson, C. (Member of programme committee), Ottosson, D. (Member of programme committee), Mårtensson, J. (Member of programme committee), Heuer, A. (Member of programme committee), Mattsson-Carlgren, N. (Member of programme committee), Petersén, Å. (Member of programme committee), Parmar, M. (Member of programme committee), Castilla-Vallmanya, L. (Member of programme committee), Kidnapillai, S. (Organiser), Castilla-Vallmanya, L. (Organiser), Scott, S. (Invited speaker), Humbert, S. (Invited speaker), Heinrich, C. (Invited speaker), Böhme, R. (Invited speaker), Lozano, A. (Keynote/plenary speaker), Adami, A. (Presenter), Atudorei, M. (Presenter), Bergh, S. (Presenter), Gornov, A. (Presenter) & Martinez Curiel, R. (Presenter)
2025 May 8Activity: Participating in or organising an event › Organisation of conference
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Segerfalk Symposium 2024
Jakobsson, J. (Organiser), Douse, C. (Organiser), Horvath, V. (Organiser), Pettersson, P. (Organiser), Pombo, A. (Invited speaker), Bartosovic, M. (Invited speaker), Bayin, N. S. (Invited speaker), Rowe, H. M. (Invited speaker), Toda, T. (Invited speaker), Gerdes, P. (Chair), Dorazehi, F. (Chair), Castilla-Vallmanya, L. (Chair) & Garza, R. (Chair)
2024 May 15Activity: Participating in or organising an event › Organisation of conference
File
Prizes and distinction
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The Anna-Greta Crafoord Prize for Best Dissertation at the Faculty of Medicine, Lund University 2014
Åkerblom, M. (Recipient), 2015
Prize: Prize (including medals and awards)
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Neurofortis Young Investigator Award
Jakobsson, J. (Recipient), 2010
Prize: Prize (including medals and awards)
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Datasets
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Spatial Transcriptomics of the Striatum of Two Murine Parkinson's Disease Models
Graziano , M. (Creator), Mantas, I. (Creator), Masarapu, Y. (Creator), Frapard, S. (Creator), Garza, R. (Creator), Adami, A. (Creator), Fazal, S. V. (Creator), Quaegebeur, A. (Creator), Barker, R. (Creator), Jakobsson, J. (Creator), Giacomello, S. (Creator) & Meletis, K. (Creator), Zenodo, 2025 May 8
Dataset
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Single Nucleus RNA sequencing of the Striatum of Two Murine Parkinson's Disease Models
Graziano , M. (Creator), Mantas, I. (Creator), Masarapu, Y. (Creator), Frapard, S. (Creator), Garza, R. (Creator), Adami, A. (Creator), Fazal, S. V. (Creator), Quaegebeur, A. (Creator), Barker, R. (Creator), Jakobsson, J. (Creator), Giacomello, S. (Creator) & Meletis, K. (Creator), Zenodo, 2025 May 8
Dataset
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Single nuclei sequencing of brain regions from healthy and Parkinson's Disease individuals
Jakobsson, J. (Creator), Barker, R. (Creator), Gale Hammell, M. (Creator), Kirkeby, A. (Creator), Garza, R. (Creator), Sharma, Y. (Creator), Tam, O. (Creator), Wunderlich, C. (Creator), Forcier, T. (Creator), Jones, J. (Creator), Curle, A. (Creator), Quaegebeur, A. (Creator), Adami, A. (Creator), Wijesinghe, S. (Creator), Jönsson, M. (Creator), Kouli, A. (Creator) & Atacho, D. (Creator), Zenodo, 2025 Apr 6
Dataset