Molecular therapeutics in breast cancer

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Unit profile


Our ultimate research goal is to find improved ways to treat patients with metastatic breast cancer. Although significant progress in treatment strategies has been made during the last decades, many breast cancer patients still relapse and to date metastatic breast cancer remains an incurable disease. We aim to identify the signalling pathways active in recurrent disease in order to study response to targeted therapeutics against such pathways and to better understand resistance mechanisms. Ongoing projects: 1. Identification of mechanisms that cause acquired resistance to endocrine therapy in metastatic breast cancer. 2. Study of the involvement of cancer stem cells in development of resistance to endocrine treatment. 3. Study of the downstream effectors in MYC driven triple negative breast tumours to find druggable targets in this elusive subtype of breast cancer. 4. Investigate tumour evolution and development of “liquid biopsies” as a surrogate for tumour biopsies.

UKÄ subject classification

  • Cancer and Oncology

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Collaborations and top research areas from the last five years

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