• Phone+46462220559
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    Sölvegatan 19, BMC A11

    221 84 Lund

    Sweden

Unit profile

Research

We use cell sorting and cell engineering techniques to generate dopamine neuron precursor cells specifically for transplantation purposes, and explore techniques for insertion of genes into stem cells to direct the development of stem cells into transplantable midbrain dopamine neurons. In a second line of research we explore rodent models of Parkinson´s disease to study the mechanisms underlying development of L-DOPA-induced dyskinesias, and use recombinant viral vectors as tools to model Parkinson-like neurodegeneration in rodents, and for delivery of putative therapeutic factors, GDNF and Nurr 1 in particular, to the brain.

Description

Our research aims at developing new restorative and neuroprotective treatments for neurodegenerative diseases using cell transplantation and direct in vivo gene delivery. The Neurobiology Unit seeks to develop techniques for isolation and identification of neural progenitor cells with the capacity to generate fully functional dopamine neurons after transplantation to the Parkinsonian brain.

UKÄ subject classification

  • Neurosciences
  • Neurology

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Collaborations and top research areas from the last five years

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