Research output per year
Research output per year
Unit profile
Research
Soft tissue sarcomas constitute a heterogeneous group of rare tumours with some 50 histopathologic types with different clinical characteristics and prognosis. Two thirds are highly malignant tumours and one third of the patients die due to metastatic disease. The care of sarcoma patients in the Southern Swedish health care region is centralised to the Lund Sarcoma Centre. We have a large data base with treatment and outcome data for sarcoma patients and a tissue bank with fresh frozen tumour samples. Using a translational approach, we study genetic and molecular profiles and link tumour characteristics to treatment and prognosis. The research is performed in collaboration with the Depts of Oncology, Pathology and Clinical Genetics. Findings are applied for refined diagnostics and prognostics in sarcomas with the aim of improving the care of patients with sarcoma.
UKÄ subject classification
- Cancer and Oncology
- Orthopedics
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Emelie Styring
- Orthopaedics (Lund) - Researcher
- Orthopaedic Sarcoma Research - Research project participant
Person
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Arvid von Konow
- Orthopaedic Sarcoma Research - Research project participant
- Orthopaedics (Lund) - Research student
- Teachers at the Medical Programme - Teaching staff
Person
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Fredrik Vult von Steyern
- Orthopaedics (Lund) - Supervisor
- Orthopaedic Sarcoma Research - Project manager
Person
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Transcriptomic profiles of myxofibrosarcoma and undifferentiated pleomorphic sarcoma correlate with clinical and genomic features
Mitra, S., Farswan, A., Piccinelli, P., Sydow, S., Hesla, A., Tsagkozis, P., Vult von Steyern, F., Almqvist, M., Eriksson, M., Magnusson, L., Nilsson, J., Pillay, N. & Mertens, F., 2024 Nov, In: Journal of Pathology. 264, 3, p. 293-304 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway
Saba, K. H., Difilippo, V., Kovac, M., Cornmark, L., Magnusson, L., Nilsson, J., van den Bos, H., Spierings, D. C. J., Bidgoli, M., Jonson, T., Sumathi, V. P., Brosjö, O., Staaf, J., Foijer, F., Styring, E., Nathrath, M., Baumhoer, D. & Nord, K. H., 2024 Feb, In: Journal of Pathology. 262, 2, p. 147-160 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Osteosarcomas With Few Chromosomal Alterations or Adult Onset Are Genetically Heterogeneous
Difilippo, V., Saba, K. H., Styring, E., Magnusson, L., Nilsson, J., Nathrath, M., Baumhoer, D. & Nord, K. H., 2024 Jan 1, In: Laboratory investigation; a journal of technical methods and pathology. 104, 1Research output: Contribution to journal › Article › peer-review
Open Access
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Soft Tissue Sarcoma of the Extremities and Trunk Wall – epidemiology, treatment and follow-up
von Konow, A. (Research student), Vult von Steyern, F. (Supervisor) & Styring, E. (Assistant supervisor)
2019/04/01 → …
Project: Dissertation
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Precision Medicine in Hereditary Cancer and Sarcoma; targeted surveillance, immunotherapy and individualized follow-up
Nilbert, M. (PI), Rambech, E. (Researcher), Jönsson, M. (Researcher), Styring, E. (Assistant supervisor), Nyström, H. (Research student) & Rosell, L. (Research student)
Project: Research
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Precision Medicine in Hereditary Cancer and Sarcoma; targeted surveillance, immunotherapy and individualized follow-up
Nilbert, M. (PI), Nyström, H. (Research student), Rosell, L. (Research student), Jönsson, M. (Researcher), Rambech, E. (Researcher), Peterson, S. (CoI) & Styring, E. (Assistant supervisor)
2017/01/01 → 2018/12/31
Project: Research