Research output per year
Research output per year
Unit profile
Description
David Gisselsson Nord is Research Leader for this research groupResearch
We make genetic and functional maps of cancer cell evolution in patients by analyzing multiple tumour samples from the same patient. In particular, we aim to: 1. Make phylogenetic maps of cancer cell variation over anatomic space and treatment time in order to understand the conditions leading to treatment resistance; 2. Assess the functional effect on the RNA and protein levels of genetic variation in tumours; 3. Analyze to what extent clinical biomarkers exhibit variability within a tumour lineage – a potentially important source of error in clinical decision making; 4. Evaluate the potential of using parameters of genetic variation as biomarkers for response to treatment. To reach these aims we use a combination of traditional histopathology and next-generation sequencing technologies. We focus on three of the most common solid tumours in children: neuroblastoma, Wilms tumour and rhabdomyosarcoma.UKÄ subject classification
- Genetics
- Cancer and Oncology
- Pediatrics
- Biomedical Laboratory Science/Technology
Free keywords
- Pathology
- Paediatrics
- Childhood cancer
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Natalie Andersson
- Pathways of cancer cell evolution - Doctoral student
- Division of Clinical Genetics - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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Subhayan Chattopadhyay
- Pathways of cancer cell evolution - Postdoctoral fellow
- Division of Clinical Genetics - Postdoctoral fellow
- LUCC: Lund University Cancer Centre - Researcher
Person
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9-oxo-ODAs suppresses the proliferation of human cervical cancer cells through the inhibition of CDKs and HPV oncoproteins
Mogi, K., Koya, Y., Yoshihara, M., Sugiyama, M., Miki, R., Miyamoto, E., Fujimoto, H., Kitami, K., Iyoshi, S., Tano, S., Uno, K., Tamauchi, S., Yokoi, A., Shimizu, Y., Ikeda, Y., Yoshikawa, N., Niimi, K., Yamakita, Y., Tomita, H., Shibata, K., & 3 others, 2023, In: Scientific Reports. 13, 1, 19208.Research output: Contribution to journal › Article › peer-review
Open Access -
Breast cancer associated CD169+ macrophages possess broad immunosuppressive functions but enhance antibody secretion by activated B cells
Gunnarsdottir, F. B., Briem, O., Lindgren, A. Y., Källberg, E., Andersen, C., Grenthe, R., Rosenqvist, C., Rydberg Millrud, C., Wallgren, M., Viklund, H., Bexell, D., Johansson, M. E., Hedenfalk, I., Hagerling, C. & Leandersson, K., 2023, In: Frontiers in Immunology. 14, 1180209.Research output: Contribution to journal › Article › peer-review
Open Access -
Building a precision medicine infrastructure at a national level: The Swedish experience
Edsjö, A., Lindstrand, A., Gisselsson Nord, D., Orvelid-Mölling, P., Friedman, M., Cavelier, L., Johansson, M., Ehrencrona, H., Fagerqvist, T., Strid, T., Lovmar, L., Jacobsson, B., Johansson, Å., Engstrand, L., Wheelock, C. E., Sikora, P., Wirta, V., Fioretos, T. & Rosenquist, R., 2023, In: Cambridge Prisms: Precision Medicine. 1Research output: Contribution to journal › Review article › peer-review
Open Access
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Phylogenetic analysis of pediatric tumors
Andersson, N., Gisselsson Nord, D., Valind, A. & Chattopadhyay, S.
2020/08/31 → …
Project: Dissertation
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cancer evolution in ovarian cancer and pediatric cancer in the view of microenvironment
Uno, K. & Yoshihara, M.
2019/04/01 → 2023/02/28
Project: Research
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iCOPE – the interregional Childhood Oncology Precision medicine Exploration
Schmiegelow, K., Plonk, C., Castor, A., Wadt, K., Gupta, R., Frandsen, T. L., Fioretos, T., Gisselsson Nord, D., Kristensson Hallström, I., Hansson, H., Castor, C. & Weibel, M.
2019/04/01 → 2022/09/30
Project: Research
Activities
- 4 Media participation
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Interview in national Swedish radio
David Gisselsson Nord (Role not specified)
2021 Apr 13Activity: Other › Media participation
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@DGisselsson Twitter
David Gisselsson Nord (Role not specified)
2018 Jan 1 → 2020 Jan 1Activity: Other › Media participation
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The four survival strategies of cancer cells
David Gisselsson Nord (Role not specified)
2018Activity: Other › Media participation
Prizes and distinction
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Nominated for the Early Career Awards 2023
Andersson, Natalie (Recipient), 2023 Jun 13
Prize: Prize (including medals and awards)
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Fellowship of Excellence
Andersson, Natalie (Recipient), 2023 Apr 14
Prize: Prize (including medals and awards)
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Markussens stipendium
Andersson, Natalie (Recipient), 2023 Apr 1
Prize: Prize (including medals and awards)