Protease Inhibitor Research

Lucas, R. A. I., Hansson, E., Skinner, B. D., Arias-Monge, E., Wesseling, C., Ekström, U., Weiss, I., Castellón, Z. E., Poveda, S., Cerda-Granados, F. I., Martinez-Cuadra, W. J., Glaser, J., Wegman, D. H. & Jakobsson, K., 2024, (Accepted/In press) In: European Journal of Applied Physiology.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Babesia divergens Shows Equal Predilection for Human ABO Blood Types in an In Vitro Erythrocyte Preference Assay.

Tijani, M. K., Danielsson, L., Storry, J. R., Olsson, M. L. & Persson, K. E. M., 2023 Jun 5, In: Pathogens. 12, 6, p. 1-10

Research output: Contribution to journal › Article › peer-review

Open Access

An explorative study of inflammation-related proteins associated with kidney injury in male heat-stressed workers

Hansson, E., Broberg, K., Wijkström, J., Glaser, J., Gonzalez-Quiroz, M., Ekström, U., Abrahamson, M. & Jakobsson, K., 2023 Feb, In: Journal of Thermal Biology. 112, 103433.

Research output: Contribution to journal › Article › peer-review

Acquisition of complement fixing antibodies targeting Plasmodium falciparum merozoites in infants and their mothers in Uganda

Mortazavi, S. E., Lugaajju, A., Nylander, M., Danielsson, L., Tijani, M. K., Beeson, J. G. & Persson, K. E. M., 2023, In: Frontiers in Immunology. 14, 1295543.

Research output: Contribution to journal › Article › peer-review

Open Access

The complexity of kidney disease and diagnosing it - Cystatin C, selective glomerular hypofiltration syndromes and proteome regulation

Malmgren, L., Öberg, C., den Bakker, E., Leion, F., Siódmiak, J., Åkesson, A., Lindström, V., Herou, E., Dardashti, A., Xhakollari, L., Grubb, G., Strevens, H., Abrahamson, M., Helmersson-Karlqvist, J., Magnusson, M., Björk, J., Nyman, U., Ärnlöv, J., Ridefeldt, P. & Åkerfeldt, T. & 18 others, Hansson, M., Sjöström, A., Mårtensson, J., Itoh, Y., Grubb, D., Tenstad, O., Hansson, L.-O., Olafsson, I., Campos, A. J., Risch, M., Risch, L., Larsson, A., Nordin, G., Pottel, H., Christensson, A., Bjursten, H., Bökenkamp, A. & Grubb, A., 2023, In: Journal of Internal Medicine. 293, 3, p. 293-308

Research output: Contribution to journal › Review article › peer-review

Open Access

2022

Point-of-care biomarkers for prediction of kidney function trajectory among sugarcane cutters: a comparative test accuracy study

Hansson, E., Wesseling, C., Wegman, D., Ekström, U., Chavarria, D., Glaser, J. & Jakobsson, K., 2022 Nov 18, In: BMJ Open. 12, 11, e060364.

Research output: Contribution to journal › Article › peer-review

Open Access

Large difference but high correlation between creatinine and cystatin C estimated glomerular filtration rate in Mesoamerican sugarcane cutters

Andersson, A., Hansson, E., Ekstrom, U., Grubb, A., Abrahamson, M., Jakobsson, K. & Xu, Y., 2022 Jul 1, In: Occupational and Environmental Medicine. 79, 7, p. 497-502 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Simultaneous determination of folate and methotrexate metabolites in serum by LC-MS/MS during high-dose methotrexate therapy

Hansson, K., Orrling, H., Blomgren, A., Isaksson, A., Schliamser, G., Heldrup, J. & Pronk, C. J., 2021 Dec 1, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1186, 123007.

Research output: Contribution to journal › Article › peer-review

Open Access

Cellular Effects of Cystatins

Hunaiti, S., 2021, Lund: Lund University, Faculty of Medicine. 74 p.

Research output: Thesis › Doctoral Thesis (compilation)

Open Access

File

112 Downloads (Pure)

2020

Effectiveness and Safety of the European Society of Cardiology 0-/1-h Troponin Rule-Out Protocol: The Design of the ESC-TROP Multicenter Implementation Study

Mokhtari, A., Khoshnood, A., Lundager Forberg, J., Hård Af Segerstad, C., Ekström, U., Schyman, T., Akbarzadeh Mameghanilar, M., Lindahl, B. & Ekelund, U., 2020 Nov, In: Cardiology. 145, 11, p. 685-692 8 p.

Research output: Contribution to journal › Article › peer-review

Pregnancy-induced changes in serum concentrations of perfluoroalkyl substances and the influence of kidney function

Nielsen, C., Andersson Hall, U., Lindh, C., Ekström, U., Xu, Y., Li, Y., Holmäng, A. & Jakobsson, K., 2020 Jul 8, In: Environmental Health: A Global Access Science Source. 19, 1, 80.

Research output: Contribution to journal › Article › peer-review

Open Access

Preventing kidney injury among sugarcane workers: Promising evidence from enhanced workplace interventions

Glaser, J., Hansson, E., Weiss, I., Wesseling, C., Jakobsson, K., Ekström, U., Apelqvist, J., Lucas, R., Arias Monge, E., Peraza, S., Hogstedt, C. & Wegman, D. H., 2020 Jul, In: Occupational and environmental medicine. 77, 8, p. 527-534 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Pathophysiological mechanisms by which heat stress potentially induces kidney inflammation and chronic kidney disease in sugarcane workers

Hansson, E., Glaser, J., Jakobsson, K., Weiss, I., Wesseling, C., Lucas, R. A. I., Wei, J. L. K., Ekström, U., Wijkström, J., Bodin, T., Johnson, R. J. & Wegman, D. H., 2020 Jun 2, In: Nutrients. 12, 6, 1639.

Research output: Contribution to journal › Article › peer-review

Open Access

Swedish national survey on MR safety compared with CT: a false sense of security?

Hansson, B., Olsrud, J., Wilén, J., Owman, T., Höglund, P. & Björkman-Burtscher, I. M., 2020 Apr, In: European Radiology. 30, 4, p. 1918-1926 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Shrunken Pore Syndrome Is Associated With Increased Levels of Atherosclerosis-Promoting Proteins

Sällman Almén, M., Björk, J., Nyman, U., Lindström, V., Jonsson, M., Abrahamson, M., Schiller Vestergren, A., Lindhe, Ö., Franklin, G., Christensson, A. & Grubb, A., 2019 Jan, In: Kidney International Reports. 4, 1, p. 67-79

Research output: Contribution to journal › Article › peer-review

Open Access

Workload and cross-harvest kidney injury in a Nicaraguan sugarcane worker cohort

Hansson, E., Glaser, J., Weiss, I., Ekström, U., Apelqvist, J., Hogstedt, C., Peraza, S., Lucas, R., Jakobsson, K., Wesseling, C. & Wegman, D. H., 2019, In: Occupational and environmental medicine. 76, 11, p. 818-826 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Improving prediction of heart transplantation outcome using deep learning techniques

Medved, D., Ohlsson, M., Höglund, P., Andersson, B., Nugues, P. & Nilsson, J., 2018 Feb 26, In: Scientific Reports. 8, 9 p., 3613 .

Research output: Contribution to journal › Article › peer-review

Open Access

A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer

Wendel, U., Persson, N., Risinger, C., Bengtsson, E., Nodin, B., Danielsson, L., Welinder, C., Fredrikson, G. N., Jansson, B. & Blixt, O., 2018 Feb 1, In: PLoS ONE. 13, 2, e0191872.

Research output: Contribution to journal › Article › peer-review

Open Access

Methodological and clinical evaluation of the alcohol marker phosphatidylethanol (PEth)

Walther, L., 2018, Lund: Lund University: Faculty of Medicine. 71 p.

Research output: Thesis › Doctoral Thesis (compilation)

1 Downloads (Pure)

2017

Long-term patient survival in a Swedish population-based cohort of patients with ANCA-associated vasculitis

Heijl, C., Mohammad, A. J., Westman, K. & Höglund, P., 2017 Jul 1, In: RMD Open. 3, 1, e000435.

Research output: Contribution to journal › Article › peer-review

Open Access

Negative anti-neutrophil cytoplasm antibody at switch to maintenance therapy is associated with a reduced risk of relapse

Morgan, M. D., Szeto, M., Walsh, M., Jayne, D., Westman, K., Rasmussen, N., Hiemstra, T. F., Flossmann, O., Berden, A., Höglund, P., Harper, L. & European Vasculitis Society, 2017 Jun 7, In: Arthritis Research and Therapy. 19, 1, 129.

Research output: Contribution to journal › Article › peer-review

Open Access

Low-level internalization of cystatin E/M affects legumain activity and migration of melanoma cells

Wallin, H., Apelqvist, J., Andersson, F., Ekström, U. & Abrahamson, M., 2017, In: Journal of Biological Chemistry. 292, 35, p. 14413-14424 12 p.

Research output: Contribution to journal › Article › peer-review

Prognostic factors for outcome of benign skull base lesions: The vestibular schwannoma model

Al-Shudifat, A. R. M., 2017, Lund: Lund University: Faculty of Medicine. 68 p.

Research output: Thesis › Doctoral Thesis (compilation)

Open Access

File

568 Downloads (Pure)

2015

Calcium Regulates the Activity and Structural Stability of Tpr, a Bacterial Calpain-like Peptidase.

Staniec, D., Ksiazek, M., Thøgersen, I. B., Enghild, J. J., Sroka, A., Bryzek, D., Bogyo, M., Abrahamson, M. & Potempa, J., 2015, In: Journal of Biological Chemistry. 290, 45, p. 27248-27260

Research output: Contribution to journal › Article › peer-review

2014

Fertility Defects in Mice Expressing the L68Q Variant of Human Cystatin C A ROLE FOR AMYLOID IN MALE INFERTILITY

Whelly, S., Serobian, G., Borchardt, C., Powell, J., Johnson, S., Håkansson, K., Lindström, V., Abrahamson, M., Grubb, A. & Cornwall, G. A., 2014, In: Journal of Biological Chemistry. 289, 11, p. 7718-7729

Research output: Contribution to journal › Article › peer-review

2013

Cystatin C properties crucial for uptake and inhibition of intracellular target enzymes.

Wallin, H., Abrahamson, M. & Ekström, U., 2013, In: Journal of Biological Chemistry. 288, 23, p. 17019-17029

Research output: Contribution to journal › Article › peer-review

File

217 Downloads (Pure)

Cysteine proteinase inhibitors regulate human and mouse osteoclastogenesis by interfering with RANK signaling

Stralberg, F., Henning, P., Gjertsson, I., Kindlund, B., Souza, P. P. C., Persson, E., Abrahamson, M., Kasprzykowski, F., Grubb, A. & Lerner, U. H., 2013, In: FASEB Journal. 27, 7, p. 2687-2701

Research output: Contribution to journal › Article › peer-review

Stabilization, Characterization and Selective Removal of Cystatin C Amyloid Oligomers.

Ranheimer Östner, G., Lindström, V., Hjort Christensen, P., Kozak, M., Abrahamson, M. & Grubb, A., 2013, In: Journal of Biological Chemistry. 288, 23, p. 16438-16450

Research output: Contribution to journal › Article › peer-review

File

203 Downloads (Pure)

2012

Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment

Laurent-Matha, V., Huesgen, P. F., Masson, O., Derocq, D., Prebois, C., Gary-Bobo, M., Lecaille, F., Rebiere, B., Meurice, G., Orear, C., Hollingsworth, R. E., Abrahamson, M., Lalmanach, G., Overall, C. M. & Liaudet-Coopman, E., 2012, In: FASEB Journal. 26, 12, p. 5172-5181

Research output: Contribution to journal › Article › peer-review

2011

Cleavage of IgG1 and IgG3 by gingipain K from Porphyromonas gingivalis may compromise host defense in progressive periodontitis.

Vincents, B., Guentsch, A., Kostolowska, D., von Pawel-Rammingen, U., Eick, S., Potempa, J. & Abrahamson, M., 2011, In: FASEB Journal. 25, 10, p. 3741-3750

Research output: Contribution to journal › Article › peer-review

2010

Cystatin E/M suppresses legumain activity and invasion of human melanoma

Briggs, J. J., Haugen, M. H., Johansen, H. T., Riker, A. I., Abrahamson, M., Fodstad, O., Maelandsmo, G. M. & Solberg, R., 2010, In: BMC Cancer. 10

Research output: Contribution to journal › Article › peer-review

Open Access

2009

Drug-related problems in the elderly

Midlöv, P., Eriksson, T. & Kragh, A., 2009 Dec 1, Springer. 135 p.

Research output: Book/Report › Book › Research › peer-review

2008

Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin

Redzynia, I., Ljunggren, A., Abrahamson, M., Mort, J. S., Krupa, J. C., Jaskolski, M. & Bujacz, G., 2008, In: Journal of Biological Chemistry. 283, 33, p. 22815-22825

Research output: Contribution to journal › Article › peer-review

Open Access

2001

Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping

Janowski, R., Kozak, M., Jankowska, E., Grzonka, Z., Grubb, A., Abrahamson, M. & Jaskolski, M., 2001, In: Nature Structural Biology. 8, 4, p. 316-320

Research output: Contribution to journal › Article › peer-review

File

716 Downloads (Pure)

1989

Pharmacokinetic comparison of two models of endocarditis prophylaxis with amoxycillin

Paulsen, O., Höglund, P. & Schalén, C., 1989, In: Scandinavian Journal of Infectious Diseases. 21, 6, p. 669-73

Research output: Contribution to journal › Article › peer-review

1987

Liquid chromatographic determination of diltiazem and its metabolites using trans isomers as internal standards, with dynamic modification of the solid phase by addition of an amine to the mobile phase

Höglund, P. & Nilsson, L. G., 1987 Feb 20, In: Journal of Chromatography. B. 414, 1, p. 109-20

Research output: Contribution to journal › Article › peer-review

Interaction between isoniazid and theophylline

Höglund, P., Nilsson, L. G. & Paulsen, O., 1987 Feb, In: European Journal of Respiratory Diseases. 70, 2, p. 110-6

Research output: Contribution to journal › Article › peer-review

The interaction of erythromycin with theophylline

Paulsen, O., Höglund, P., Nilsson, L. G. & Bengtsson, H. I., 1987, In: European Journal of Clinical Pharmacology. 32, 5, p. 493-8 6 p.

Research output: Contribution to journal › Article › peer-review

1986

Antiarrhythmic effect of amperozide, a novel psychotropic compound with class III antiarrhythmic properties, on digoxin-induced arrhythmias in the guinea-pig

Höglund, P., Eriksson, M. & Christensson, E. G., 1986 Nov, In: Journal of Pharmacy and Pharmacology. 38, 11, p. 861-3

Research output: Contribution to journal › Article › peer-review

No interaction between H2 blockers and isoniazid

Paulsen, O., Höglund, P., Nilsson, L. G. & Gredeby, H., 1986 Apr, In: European Journal of Respiratory Diseases. 68, 4, p. 286-90

Research output: Contribution to journal › Article › peer-review

Protease Inhibitor Research

Research output

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