Research output per year
Research output per year
Unit profile
Description
Our research is focused on the regulation of the complement system in health and disease. Complement is crucial part of innate immunity and thus protects host from infections and contributes to removal of dying cells. We study involvement of complement in pathology of rheumatic and inflammatory diseases as well as several types of cancer. Further, we investigate strategies developed by bacterial pathogens in order to avoid killing by complement, which results in infections. Our main focus is on various complement inhibitors such as C4BP and factor I but also newly discovered regulators such as SUSD4, CSMD1 and COMP. Recently we expanded our research into intracellular functions of complement proteins in particular in pancreatic beta cells.Research
Anna Blom is Research Group Leader for this research groupUKÄ subject classification
- Cancer and Oncology
- Immunology in the medical area
- Microbiology in the medical area
- Rheumatology and Autoimmunity
Free keywords
- Complement system
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Anna Blom
- Protein Chemistry, Malmö - Manager, Professor, Research team manager, Principal investigator
- Department of Translational Medicine - Assistant head of department
- EXODIAB: Excellence of Diabetes Research in Sweden - Principal investigator
- LUCC: Lund University Cancer Centre - Principal investigator
Person: Academic
Research output
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C4b-binding protein inhibits particulate- and crystalline-induced NLRP3 inflammasome activation
Bierschenk, D., Papac-Milicevic, N., Bresch, I. P., Kovacic, V., Bettoni, S., Dziedzic, M., Wetsel, R. A., Eschenburg, S., Binder, C. J., Blom, A. M. & King, B. C., 2023, In: Frontiers in Immunology. 14, 1149822.Research output: Contribution to journal › Article › peer-review
Open Access -
Complement activation negatively affects the platelet response to thrombopoietin receptor agonists in patients with immune thrombocytopenia: a prospective cohort study
Åkesson, A., Bussel, J. B., Martin, M., Blom, A. M., Klintman, J., Ghanima, W., Zetterberg, E. & Garabet, L., 2023 Jan 13, In: Platelets. 34, 1, p. 1-9 2159019.Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluation of Glycosaminoglycans Biological Age in Cells and Tissues
Gialeli, C. & Gonçalves, I., 2023, Proteoglycans: Methods and Protocols. Vol. 2619. p. 91-98 (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Identification of novel complement evasion mechanisms developed by bacterial pathogens.
Magda, M., Blom, A., Bettoni, S. & Rooijakkers, S.
2020/04/01 → …
Project: Dissertation
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Alternative roles of complement inhibitors in cancer
Gunnar Nilssons cancerstiftelse, Cancerfonden
2018/01/01 → 2024/12/31
Project: Research
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Non-traditional functions of the Complement System proteins
Golec, E., Blom, A. & King, B.
2017/09/01 → …
Project: Dissertation
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Exodiab mini-symposium
Peter Spégel (Invited speaker), Ben King (Invited speaker), S Albert Salehi (Invited speaker), Malin Fex (Invited speaker) & Maria Gomez (Chair)
2018 Nov 27Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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Chair of the Board of Medicine at the Swedish Research Council
Anna Blom (Chair)
2016 → 2021Activity: Consultancy, expert advice and memberships › Member of board/committee/council etc
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Board Member at Åke Wiberg Foundation
Anna Blom (Role not specified)
2016 → …Activity: Consultancy, expert advice and memberships › Member of board/committee/council etc
Prizes and distinction
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Doctor Honoris Causa, Rzeszow University, Poland
Blom, Anna (Recipient), 2018
Prize: National/international honour
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European Federation of Immunological Societies Lecture Award
Blom, Anna (Recipient), 2015
Prize: Prize (including medals and awards)