Research output per year
Research output per year
Unit profile
Description
Our research is focused on the regulation of the complement system in health and disease. Complement is crucial part of innate immunity and thus protects host from infections and contributes to removal of dying cells. We study involvement of complement in pathology of rheumatic and inflammatory diseases as well as several types of cancer. Further, we investigate strategies developed by bacterial pathogens in order to avoid killing by complement, which results in infections. Our main focus is on various complement inhibitors such as C4BP and factor I but also newly discovered regulators such as SUSD4, CSMD1 and COMP. Recently we expanded our research into intracellular functions of complement proteins in particular in pancreatic beta cells.
Subject classification (UKÄ)
- Cancer and Oncology
- Immunology in the Medical Area (including Cell and Immunotherapy)
- Microbiology in the Medical Area
- Clinical Medicine
- Basic Cancer Research
Free keywords
- Complement system
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Anna Blom
- Protein Chemistry, Malmö - Principal investigator, Manager, Research team manager, Professor
- Department of Translational Medicine - Assistant head of department
- EXODIAB: Excellence of Diabetes Research in Sweden - Member of Strategic Research Area
- LUCC: Lund University Cancer Centre - Member of research environment
Person: Academic
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Research output
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Beta-2-microglobulin augments neutrophil phagocytosis of bacteria and apoptotic cells
Poulsen, S. E., Magda, M., Blom, A. M. & Nissen, M. H., 2026 Dec, In: Immunology Letters. 282, 107221.Research output: Contribution to journal › Article › peer-review
Open Access -
Activation of the complement lectin pathway is associated with long-term cardiac dysfunction and incident heart failure in acute coronary syndrome patients
Zhong, B., King, B., Mares, R. G., Arbanasi, E. M., Yndigegn, T., Engelbertsen, D., Björkbacka, H., Nilsson, J., Goncalves, I., Blom, A. & Schiopu, A., 2026 Nov 1, In: International Journal of Cardiology. 462, 134699.Research output: Contribution to journal › Article › peer-review
Open Access -
The CLEC7A Y238∗ variant and susceptibility to pneumonia: a prospective population-based cohort study and mechanistic investigation
Thofte, O., Öhnström, V., Yamba, L. Y., Memon, A., Grundberg, A., Su, Y.-C., Slevogt, H., Zipfel, P. F., Scavenius, C., Steimbrüch, B., Leandersson, K., Håkansson, A. P., Sundquist, K., Melander, O., Blom, A. M. & Riesbeck, K., 2026 Oct 8, In: EBioMedicine. 133, p. 1-21 106497.Research output: Contribution to journal › Article › peer-review
Open Access
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Development of new cancer immunotherapy
Blom, A. (PI)
Familjen Erling-Perssons Stiftelse
2026/01/01 → 2028/12/31
Project: Research
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Roles of the complement system in diabetic immunometabolism
King, B. (PI)
Dir Albert Påhlssons stiftelse för forskning och välgörenhet
2025/01/01 → 2026/12/31
Project: Research
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Exodiab mini-symposium
Spégel, P. (Invited speaker), King, B. (Invited speaker), Salehi, S. A. (Invited speaker), Fex, M. (Invited speaker) & Gomez, M. (Chair)
2018 Nov 27Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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Chair of the Board of Medicine at the Swedish Research Council
Blom, A. (Chair)
2016 → 2021Activity: Consultancy, expert advice and memberships › Member of board/committee/council etc
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Board Member at Åke Wiberg Foundation
Blom, A. (Role not specified)
2016 → …Activity: Consultancy, expert advice and memberships › Member of board/committee/council etc
Prizes and distinction
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The Anna-Greta Crafoord Prize for Best Dissertation at the Faculty of Medicine, Lund University 2022
Golec, E. (Recipient), 2023
Prize: Prize (including medals and awards)
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Doctor Honoris Causa, Rzeszow University, Poland
Blom, A. (Recipient), 2018
Prize: National/international honour