Research output per year
Research output per year
Unit profile
Research
The overarching goal of the lab is to understand the factors that allow for highly regenerative species to perform remarkable acts of regeneration (e.g. limb regeneration). We tackle these question using salamanders as a model system. We are particularly focused on how the immune system promotes and allow for regeneration in salamanders. We apply a variety of wet lab techniques coupled with high throughput computational approaches to probe the pro-regenerative immune response required to facilitate regeneration.Description
Nicholas Leigh is Research Group Leader for this research groupUKÄ subject classification
- Immunology in the medical area
- Developmental Biology
Free keywords
- Regenerative medicine
- stem cells
- haematopoiesis
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Joseph Cardiello
- Regenerative Immunology - Postdoctoral fellow
- Division of Molecular Medicine and Gene Therapy - Postdoctoral fellow
Person
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Ameneh Ghaffarinia
- Regenerative Immunology - Postdoctoral fellow
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Postdoctoral fellow
Person
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Chimezie Harrison Umeano
- Division of Molecular Medicine and Gene Therapy - Laboratory assistant
- Regenerative Immunology - Laboratory assistant
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Laboratory assistant
Person
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Best Practices to Promote Data Utility and Reuse by the Non-Traditional Model Organism Community
Dunlap, G. S. & Leigh, N. D., 2023, In: Methods in molecular biology (Clifton, N.J.). 2562, p. 461-469 9 p.Research output: Contribution to journal › Article
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Evaluation of genetic demultiplexing of single-cell sequencing data from model species
Cardiello, J. F., Joven Araus, A., Giatrellis, S., Helsens, C., Simon, A. & Leigh, N. D., 2023 Aug, In: Life Science Alliance. 6, 8Research output: Contribution to journal › Article › peer-review
Open Access -
Cell-type profiling in salamanders identifies innovations in vertebrate forebrain evolution
Woych, J., Ortega Gurrola, A., Deryckere, A., Jaeger, E. C. B., Gumnit, E., Merello, G., Gu, J., Joven Araus, A., Leigh, N. D., Yun, M., Simon, A. & Tosches, M. A., 2022, In: Science (New York, N.Y.). 377, 6610, p. 1-11 eabp9186.Research output: Contribution to journal › Article › peer-review
Projects
- 2 Active
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Investigation into the adaptive immune system in Pleurodeles waltl
2023/04/11 → …
Project: Dissertation
Activities
- 1 Media participation
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Regeneration, a Natural Reprogramming Process-An Interview with Dr. Nicholas Leigh
Nicholas Leigh (Interviewee)
2022 Feb 15Activity: Other › Media participation
Prizes and distinction
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Docent in Molecular Medicine
Leigh, Nicholas (Recipient), 2023 Oct 2
Prize: Prize (including medals and awards)