Research output per year
Research output per year
Unit profile
Research
The overarching goal of the lab is to understand the factors that allow for highly regenerative species to perform remarkable acts of regeneration (e.g. limb regeneration). We tackle these question using salamanders as a model system. We are particularly focused on how the immune system promotes and allow for regeneration in salamanders. We apply a variety of wet lab techniques coupled with high throughput computational approaches to probe the pro-regenerative immune response required to facilitate regeneration.
UKÄ subject classification
- Immunology in the medical area
- Developmental Biology
Free keywords
- Regenerative medicine
- stem cells
- haematopoiesis
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Ameneh Ghaffarinia
- Regenerative Immunology - Postdoctoral fellow
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Postdoctoral fellow
Person
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Elsa Görsch
- Regenerative Immunology - Postdoctoral fellow
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Postdoctoral fellow
Person
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Chimezie Harrison Umeano
- Division of Molecular Medicine and Gene Therapy - Laboratory assistant
- Regenerative Immunology - Laboratory assistant
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Laboratory assistant
Person
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The Impact of Senescent Cells on Limb Regeneration
Oesterle, M. J. & Leigh, N. D., 2024 Jun, In: Cellular Reprogramming. 26, 3, p. 91-92Research output: Contribution to journal › Debate/Note/Editorial
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Label-FreeHigh-ResolutionPhotothermalOpticalInfraredSpectroscopyfor Spatiotemporal Chemica lAnalysis in Fresh, Hydrated Living Tissues and Embryos
Gvazava, N., Konings, S., Cepeda-Prado, E., Skoryk, V., Harrison Umeano, C., Dong, J., Augusto Silva, I., Rylander Ottosson , D., Leigh, N., Wagner, D. & Klementieva, O., 2023 Nov 2, In: Journal of the American Chemical Society.Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluation of genetic demultiplexing of single-cell sequencing data from model species
Cardiello, J. F., Joven Araus, A., Giatrellis, S., Helsens, C., Simon, A. & Leigh, N. D., 2023 Aug, In: Life Science Alliance. 6, 8Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 4 Active
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Deciphering the balance between regeneration and tumorigenesis
Leigh, N. (PI)
2024/01/01 → 2026/12/31
Project: Research
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Identifying the origins of cancer resistance in salamanders
Leigh, N. (Researcher)
2023/09/21 → 2026/09/21
Project: Research
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UniStem Day 2024: Dissemination and outreach of stem cell science
Ottosson, D. (Organiser), Magnusson, M. (Organiser), Kidnapillai, S. (Organiser), Ahlenius, H. (Organiser), Luis, A. B. (Organiser), Martinez Curiel, R. (Organiser), Laurin, K. (Organiser), Martos Salvo, P. (Organiser), Das, M. (Contributor), Wendler, M. (Contributor), Sivani, B. M. (Contributor), Ramos Passarello, G. (Contributor), Sozzi, E. (Contributor), García Garrote, M. (Contributor), Harrison Umeano, C. (Contributor), Okeke, U. C. (Contributor), Horvath, V. (Contributor), Garza, R. (Contributor), Adami, A. (Contributor), Castilla-Vallmanya, L. (Contributor), Gerdes, P. (Contributor), Pandiloski, N. (Contributor), Jin, Q. (Contributor), de Guidi, C. (Contributor), Palma Tortosa, S. (Contributor), Fritze, J. (Contributor), Jansson, L. I. (Contributor), Robles Rodriguez, L. (Contributor), Pracucci, E. (Contributor), Shen, Y.-P. (Contributor), Trovato, F. (Contributor), Tampé, J. (Contributor), Thakore, R. (Contributor), Stamouli, C.-A. (Contributor), Pinto dos Santos Vaz, C. (Contributor), Aretio, C. (Contributor), Piochon, C. (Contributor), Cepeda-Prado, E. (Contributor), de Jongh, M.-M. (Contributor), Tsalkitzidou, M. (Contributor), Bonsberger, J. (Contributor), Douse, C. (Contributor), Dorazehi, F. (Contributor), Koutounidou, S. (Contributor), Jarl, U. (Contributor), Corsi, S. (Contributor), Bruzelius, A. (Contributor), Mattsson, B. (Contributor), Hammarberg, A. (Contributor), Habekost, M. (Contributor), Prabhala, P. (Contributor), Bremborg, T. (Contributor), Nair, M. S. (Contributor), Burdeyron, P. (Contributor), Mazariegos, M. (Contributor), Björklund, M. (Contributor), Hidalgo, I. (Contributor), Hägg, A. (Invited speaker), Hammarlund, E. (Invited speaker), Mohlin, S. (Invited speaker) & Oesterle, M. (Contributor)
2024 Mar 22Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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Regeneration, a Natural Reprogramming Process-An Interview with Dr. Nicholas Leigh
Leigh, N. (Interviewee)
2022 Feb 15Activity: Other › Media participation
Prizes and distinction
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Docent in Molecular Medicine
Leigh, N. (Recipient), 2023 Oct 2
Prize: Prize (including medals and awards)