SciLifeLab Site@Lund

Research output

Research output per year 2023 2023 2024 2024

• 16 Article
• 1 Review article
• 1 Doctoral Thesis (compilation)
• 1 Preprint (in preprint archive)

Research output per year

Research output per year

Search results

• 2024

  Cerebrospinal fluid reference proteins increase accuracy and interpretability of biomarkers for brain diseases

  Karlsson, L., Vogel, J., Arvidsson, I., Åström, K., Janelidze, S., Blennow, K., Palmqvist, S., Stomrud, E., Mattsson-Carlgren, N. & Hansson, O., 2024 Dec, In: Nature Communications. 15, 1, 3676.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Liquid 100%
  • Protein 100%
  • Encephalopathy 100%
  • Brain Disease 100%
  • Alzheimer's Disease 50%

• Mammalian cell display with automated oligo design and library assembly allows for rapid residue level conformational epitope mapping

  Thalén, N. B., Karlander, M., Lundqvist, M., Persson, H., Hofström, C., Turunen, S. P., Godzwon, M., Volk, A. L., Malm, M., Ohlin, M. & Rockberg, J., 2024 Dec, In: Communications Biology. 7, 1, 805.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mammalian Cell 100%
  • Epitope 100%
  • Antigen 80%
  • Eicosanoid Receptor 50%
  • Surface Property 50%

• Predicting type 2 diabetes via machine learning integration of multiple omics from human pancreatic islets

  Rönn, T., Perfilyev, A., Oskolkov, N. & Ling, C., 2024 Dec, In: Scientific Reports. 14, 1, 14637.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Single Nucleotide Polymorphism 100%
  • Phenotype 25%
  • Insulin Release 25%
  • RNA 25%
  • TXNIP 25%

• Maculopathy and adult-onset ataxia in patients with biallelic MFSD8 variants

  Dobloug, S., Kjellström, U., Anderson, G., Gardner, E., Mole, S. E., Sheth, J. & Puschmann, A., 2024 Aug, In: Molecular Genetics and Genomic Medicine. 12, 8, e2505.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gene 100%
  • Ataxia 100%
  • Major Facilitator Superfamily 100%
  • Retinal Dystrophy 42%
  • Macular Dystrophy 28%

• Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding

  Bimai, O., Banerjee, I., Grinberg, I. R., Huang, P., Hultgren, L., Ekström, S., Lundin, D., Sjöberg, B-M. & Logan, D. T., 2024 Jul 5, In: eLife. 12, 35 p., RP89292.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ribonucleotide Reductase 100%
  • Enzyme 11%
  • Dynamics 11%
  • Regulatory Mechanism 11%
  • N-Terminus 11%

• Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture-Based Gene Panel

  the SciLifeLab Clinical Genomics Platform and Genomic Medicine Sweden, 2024 Jul, In: Genes Chromosomes and Cancer. 63, 7, e23257.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gene 100%
  • Myeloid 100%
  • Sensitive Detection 8%

• Mechanisms of neutralization of toxSAS from toxin-antitoxin modules

  Dominguez-Molina, L., Kurata, T., Cepauskas, A., Echemendia-Blanco, D., Zedek, S., Talavera-Perez, A., Atkinson, G. C., Hauryliuk, V. & Garcia-Pino, A., 2024 Jun 4, (E-pub ahead of print) In: Nature Chemical Biology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transfer RNA 100%
  • Enzyme 50%
  • Synthesis 50%
  • Binding Site 50%
  • Enzyme Specificity 50%

• Multimodal Mass Spectrometry Identifies a Conserved Protective Epitope in S. pyogenes Streptolysin O

  Tang, D., Gueto-Tettay, C., Hjortswang, E., Ströbaek, J., Ekström, S., Happonen, L., Malmström, L. & Malmström, J., 2024 Jun 4, In: Analytical Chemistry. 96, 22, p. 9060–9068

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mass Spectrometry 100%
  • Epitope 100%
  • Streptolysin 100%
  • Monoclonal Antibody 28%
  • Heavy Chain 14%

• Biomarker-based staging of Alzheimer disease: rationale and clinical applications

  Therriault, J., Schindler, S. E., Salvadó, G., Pascoal, T. A., Benedet, A. L., Ashton, N. J., Karikari, T. K., Apostolova, L., Murray, M. E., Verberk, I., Vogel, J. W., La Joie, R., Gauthier, S., Teunissen, C., Rabinovici, G. D., Zetterberg, H., Bateman, R. J., Scheltens, P., Blennow, K., Sperling, R., & 3 othersHansson, O., Jack, C. R. & Rosa-Neto, P., 2024, In: Nature Reviews Neurology. 20, 4, p. 232–244 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Disease 100%
  • Biological Marker 100%
  • Amyloid 100%
  • In Vivo 75%
  • Brain 25%

• Disease staging of Alzheimer’s disease using a CSF-based biomarker model

  Salvadó, G., Horie, K., Barthélemy, N. R., Vogel, J. W., Pichet Binette, A., Chen, C. D., Aschenbrenner, A. J., Gordon, B. A., Benzinger, T. L. S., Holtzman, D. M., Morris, J. C., Palmqvist, S., Stomrud, E., Janelidze, S., Ossenkoppele, R., Schindler, S. E., Bateman, R. J. & Hansson, O., 2024, (E-pub ahead of print) In: Nature Aging.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Liquid 100%
  • Clinical Trial 33%
  • Tau 33%

• Exonic trinucleotide repeat expansions in ZFHX3 cause spinocerebellar ataxia type 4: A poly-glycine disease

  Wallenius, J., Kafantari, E., Jhaveri, E., Gorcenco, S., Ameur, A., Karremo, C., Dobloug, S., Karrman, K., de Koning, T., Ilinca, A., Landqvist Waldö, M., Arvidsson, A., Persson, S., Englund, E., Ehrencrona, H. & Puschmann, A., 2024, In: American Journal of Human Genetics. 111, 1, p. 82-95

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Trinucleotide Repeat Expansion 100%
  • Zinc Finger 100%
  • Homeobox 100%
  • Trinucleotide Repeat 100%
  • Phenotype 50%

• Pancreatic cancer evolution across space and time: From diagnosis to terminal disease

  Petersson, A., 2024, Lund: Lund University, Faculty of Medicine. 141 p.

  Research output: Thesis › Doctoral Thesis (compilation)

  Open Access

  File
  99 Downloads (Pure)
• 2023

  Protective non-neutralizing mAbs Ab94 and Ab81 retain high-affinity and potent Fc-mediated function against SARS-CoV-2 variants from Omicron to XBB1.5

  Izadi, A., Godzwon, M., Ohlin, M. & Nordenfelt, P., 2023 Sept 29, bioRxiv.

  Research output: Working paper/Preprint › Preprint (in preprint archive)

  • Severe Acute Respiratory Syndrome Coronavirus 2 100%
  • Omicron Coronavirus Variant 100%
  • Epitope 28%
  • Receptor Binding 14%
  • Amino Terminal Sequence 14%

• Comparisons of Different Carbohydrate Quality Indices for Risk of Type 2 Diabetes in the Malmö Diet and Cancer Study

  Ramstedt, M., Janzi, S., Olsson, K., González-Padilla, E., Ramne, S., Borné, Y., Ericson, U. & Sonestedt, E., 2023 Sept 5, In: Nutrients. 15, 18, p. 1-11 3870.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Maturity Onset Diabetes of the Young 100%
  • Carbohydrates 100%
  • Diet and Cancer 100%
  • Diet 100%
  • Association 42%

• An Okinawan-Based Nordic Diet Leads to Profound Effects on Gut Microbiota and Plasma Metabolites Linked to Glucose and Lipid Metabolism

  Manoharan, L., Roth, B., Bang, C., Stenlund, H. & Ohlsson, B., 2023 Jul 24, In: Nutrients. 15, 14, 3273.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Blood Plasma 100%
  • Diet 100%
  • Glucose 100%
  • Inflammation 40%
  • Genus 20%

• Serum proteome profiles in patients treated with targeted temperature management after out-of-hospital cardiac arrest

  Lileikyte, G., Bakochi, A., Ali, A., Moseby-Knappe, M., Cronberg, T., Friberg, H., Lilja, G., Levin, H., Årman, F., Kjellström, S., Dankiewicz, J., Hassager, C., Malmström, J. & Nielsen, N., 2023 Jul 17, In: Intensive Care Medicine Experimental. 11, 1, 43.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Protein 100%
  • Proteome 100%
  • Cardiac Arrest 100%
  • Immune Response 30%
  • Temperature 20%

• Sag-rad: A Method for Single-Cell Population Genomics of Unicellular Eukaryotes

  Gollnisch, R., Wallenius, J., Gribble, K. E., Ahrén, D. & Rengefors, K., 2023 May 2, In: Molecular biology and evolution. 40, 5, 8 p., msad095.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cell Population 100%
  • Genetic Variability 50%
  • Biogeography 50%
  • Restriction Site Associated DNA Sequencing 50%

• Subclass-switched anti-Spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization

  Izadi, A., Hailu, A., Godzwon, M., Wrighton, S., Olofsson, B., Schmidt, T., Söderlund Strand, A., Elder, E., Appelberg, S., Valsjö, M., Larsson, O., Wendel-Hansen, V., Ohlin, M., Bahnan, W. & Nordenfelt, P., 2023 Apr 3, In: Proceedings of the National Academy of Sciences. 120, 15

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Immunoglobulin G3 100%
  • Spike 100%
  • Monoclonal Antibody 80%
  • Severe Acute Respiratory Syndrome Coronavirus 2 80%
  • Monospecific Antibody 60%

• AIRR-C IG Reference Sets: curated sets of immunoglobulin heavy and light chain germline genes

  Collins, A. M., Ohlin, M., Corcoran, M., Heather, J. M., Ralph, D., Law, M., Martínez-Barnetche, J., Ye, J., Richardson, E., Gibson, W. S., Rodriguez, O. L., Peres, A., Yaari, G., Watson, C. T. & Lees, W. D., 2023, In: Frontiers in Immunology. 14, 1330153.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gene 100%
  • Germline 100%
  • Light Chain 100%
  • Immune Receptor 100%
  • Immune System Receptors 100%