Research output per year
Research output per year
BMC A12, Sölvegatan 17
221 84 Lund
Sweden
We research the generation of the most abundant cells in our bodies, the red blood cells. We are particularly interested in how this process is regulated and what goes wrong when a failure leads to anemia. Two main aims of the group are. 1. Develop novel therapies for patients with anemia that today lack effective therapy. - From different screening and medicinal chemistry approaches we are identifying drug candidates for treatment of anemia that are validated in anemic mouse models and on cells from patients with severe congenital anemia. 2. To understand the developmental process of red blood cell formation. - The group was the first to define the genetic code that instructs a cell to become an erythropoietin-sensitive erythroblast. - Through analysis of genome wide association studies and screening the group has identified several previously unknown genes that are essential for normal red cell production.
Person
Person
Person
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Published meeting abstract › peer-review
Research output: Contribution to specialist publication or newspaper › Specialist publication article › Popular science
Flygare, J. (PI)
2022/01/01 → 2026/12/31
Project: Research
Olsson, M. L. (PI), Flygare, J. (Researcher), Ilsley, M. (Researcher) & Alattar, A. G. (Researcher)
2020/02/24 → …
Project: Research
Sen, T. (PI), Singbrant, S. (Supervisor), Richter, J. (Assistant supervisor) & Flygare, J. (PI)
2016/04/01 → …
Project: Dissertation
Pereira, C.-F. (First/primary/lead supervisor) & Flygare, J. (Second supervisor)
Activity: Examination and supervision › Supervision of PhD students
Olsson, M. L. (First/primary/lead supervisor), Vidovic, K. (Joint second supervisor) & Flygare, J. (Joint second supervisor)
Activity: Examination and supervision › Supervision of PhD students
Parmar, M. (First/primary/lead supervisor), Ottosson, D. (Second supervisor), Jakobsson, J. (Joint second supervisor), Ahlenius, H. (Commissioned member of Examining committee) & Flygare, J. (Commissioned member of Examining committee)
Activity: Examination and supervision › Supervision of PhD students