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    CRC, Hus 91 plan 12, Jan Waldenströms gata 35

    Malmö

    Sweden

Unit profile

Description

During the last 100 years, we have gradually reduced our daily physical activity. As less fit, weaker, and fatter, we have become more prone to diseases like diabetes and cardiovascular disease. The WHO reports that one in four adults do not meet the global recommended levels of physical activity. Our research unit is interested in learning how genetic variation influences skeletal muscle function and whole-body metabolism. We use translational approaches and conduct intervention studies in humans. These studies involve taking muscle biopsies. From these biopsies, muscle stem cells are isolated and later used for preclinical measurements. In our projects, we combine physiological measurements like VO2max, strength, and glucose tolerance with preclinical readouts, e.g. RNAseq, fibre typing and exon skipping. We hope that this research will lead to a new understanding of skeletal muscle function with implications primarily for human health, but also provide answers to fundamental evolutionary questions.

UKÄ subject classification

  • Endocrinology and Diabetes
  • Cardiac and Cardiovascular Systems

Free keywords

  • Type 2 diabetes

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Collaborations the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or