Translational Neurology (TNY)

  • Visiting addressShow on map

    Wallenberg Neuroscience centre

    Lund

    Sweden

Unit profile

Research

Our ultimate research vision is to discover, develop and implement novel neuroprotective and neurorestorative therapies for neurological disorders such as Parkinson’s disease, Huntingtons disease and stroke. My group works with translational research that is tightly linked to clinical research questions. Our experimental focus is to understand neurovascular disease mechanisms. We examine the dysfunction of the neurovascular unit, in particular pericytes, as key players in inflammation and neurodegeneration and as potential target cells for brain repair using in vitro and in vivo disease modeling and also clinical material. We work on cell target identification for brain repair, on novel restorative molecules as well as on the clinical implementation of stem cell and different growth factor therapies for Parkinson’s disease

UKÄ subject classification

  • Neurology

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Collaborations the last five years

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  • Mitochondrial function in peripheral blood cells across the human lifespan

    Ehinger, J. K., Westerlund, E., Frostner, E. Å., Karlsson, M., Paul, G., Sjövall, F. & Elmér, E., 2024 Dec, In: npj Aging. 10, 1, 10.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia

    Manzoni, C., Kia, D. A., Ferrari, R., Leonenko, G., Costa, B., Saba, V., Jabbari, E., Tan, M. M., Albani, D., Alvarez, V., Alvarez, I., Andreassen, O. A., Angiolillo, A., Arighi, A., Baker, M., Benussi, L., Bessi, V., Binetti, G., Blackburn, D. J. & Boada, M. & 117 others, Boeve, B. F., Borrego-Ecija, S., Borroni, B., Bråthen, G., Brooks, W. S., Bruni, A. C., Caroppo, P., Bandres-Ciga, S., Clarimon, J., Colao, R., Cruchaga, C., Danek, A., de Boer, S. C., de Rojas, I., di Costanzo, A., Dickson, D. W., Diehl-Schmid, J., Dobson-Stone, C., Dols-Icardo, O., Donizetti, A., Dopper, E., Durante, E., Ferrari, C., Forloni, G., Frangipane, F., Fratiglioni, L., Kramberger, M. G., Galimberti, D., Gallucci, M., García-González, P., Ghidoni, R., Giaccone, G., Graff, C., Graff-Radford, N. R., Grafman, J., Halliday, G. M., Hernandez, D. G., Hjermind, L. E., Hodges, J. R., Holloway, G., Huey, E. D., Illán-Gala, I., Josephs, K. A., Knopman, D. S., Kristiansen, M., Kwok, J. B., Leber, I., Leonard, H. L., Libri, I., Lleo, A., Mackenzie, I. R., Madhan, G. K., Maletta, R., Marquié, M., Maver, A., Menendez-Gonzalez, M., Milan, G., Miller, B. L., Morris, C. M., Morris, H. R., Nacmias, B., Newton, J., Nielsen, J. E., Nilsson, C., Novelli, V., Padovani, A., Pal, S., Pasquier, F., Pastor, P., Perneczky, R., Peterlin, B., Petersen, R. C., Piguet, O., Pijnenburg, Y. A., Puca, A. A., Rademakers, R., Rainero, I., Reus, L. M., Richardson, A. M., Riemenschneider, M., Rogaeva, E., Rogelj, B., Rollinson, S., Rosen, H., Rossi, G., Rowe, J. B., Rubino, E., Ruiz, A., Salvi, E., Sanchez-Valle, R., Sando, S. B., Santillo, A. F., Saxon, J. A., Schlachetzki, J. C., Scholz, S. W., Seelaar, H., Seeley, W. W., Serpente, M., Sorbi, S., Sordon, S., St George-Hyslop, P., Thompson, J. C., Van Broeckhoven, C., Van Deerlin, V. M., Van der Lee, S. J., Van Swieten, J., Tagliavini, F., van der Zee, J., Veronesi, A., Vitale, E., Waldo, M. L., Yokoyama, J. S., Nalls, M. A., Momeni, P., Singleton, A. B., Hardy, J. & Escott-Price, V., 2024 Jul 11, In: American Journal of Human Genetics. 111, 7, p. 1316-1329 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Correlation of mitochondrial respiration in platelets, peripheral blood mononuclear cells and muscle fibers

    Westerlund, E., Marelsson, S. E., Karlsson, M., Sjövall, F., Chamkha, I., Åsander Frostner, E., Lundgren, J., Fellman, V., Eklund, E. A., Steding-Ehrenborg, K., Darin, N., Paul, G., Hansson, M. J., Ehinger, J. K. & Elmér, E., 2024 Mar 15, In: Heliyon. 10, 5, e26745.

    Research output: Contribution to journal › Article › peer-review

    Open Access
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  • 6 Media participation
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