Unit for Biological and Precision Psychiatry

  • Visiting address

    Sweden

Unit profile

Description

Depression, Biomarkers, Clinical trials

Research

The overreaching hypothesis that frames our work is that depressive disorders are accompanied by, if not caused by, identifiable biological abnormalities that contribute to both the psychological and somatic aspects of these illnesses. This is a comprehensive hypothesis involving the study of several biomarkers including (but not limited to) cellular stress, inflammation, oxidative stress, mitochondrial dysfunction, vitamin D, neurotransmitters, gut microbiome and brain imaging. Treatment of depression is hampered by the failure to identify distinct symptom profiles with distinct pathophysiologies that differentially respond to distinct treatments. We use blood, brain, and feces biomarkers to delineate specific subgroups of depression, and test the antidepressant efficacy of various interventions targeting these specific biological pathways. The goal of our research program is to advance precision psychiatry by tailoring antidepressant treatments.

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Collaborations the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or