Our research group focus on different aspects of preeclampsia; 1) molecular factors involved in the etiology, e.g. free fetal hemoglobin, globin and iron, 2) understand the role of air pollution in preeclampsia etiology, 3) evaluation of the scavenger proteins hemopexin and alpha-1-microglobulin as biomarkers for preeclampsia and intra uterine growth restriction, 4) study the gastrointestinal microbiota in preeclampsia, 5) study vascular mechanisms that can be involved in the long-term risk for cardiovascular diseases after preeclampsia, 6) evaluate therapeutic approaches for preeclampsia in animal models, 7) document women’s experiences from preeclampsia, 8) evaluate psychological mechanisms involved in decision making in obstetric emergencies.
Preeclampsia is a severe pregnancy-related condition that annually affects 10M women worldwide. The etiology is largely unknown and diagnosis is currently based on maternal clinical symptoms: high blood pressure and organ damage manifesting after 20 weeks of gestation. Delivery is currently the only cure. Increased long-term risk for cardiovascular diseases and stroke after preeclampsia point to its seriousness. Reliable methods for early diagnosis and prognosis, and a safe and effective treatment are urgently needed.
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