Research output per year
Research output per year
Personal profile
Research
Dr. Alessandro Fiorenzano holds a post-doctoral position at the Department of Developmental and Regenerative Neurobiology, Lund University (Sweden), where he is working with Prof. Malin Parmar’s group. Originally from Italy, Alessandro was awarded his Bachelor's and Master's degrees in Biology from the University of Naples Federico II. He obtained his PhD in Molecular and Cellular Biotechnology at the Italian National Research Council Institute of Genetics and Biophysics, where he consolidated his background in stem cell biology. During his PhD program, he studied the impact of the extracellular microenvironment on pluripotency and differentiation of embryonic stem cells (ESCs), with particular emphasis on extrinsic and intrinsic pathways including ESC self-renewal regulation by non-coding RNAs. His current focus is on investigating the molecular mechanisms underlying neuronal specification that efficiently drive controlled differentiation of human stem cells into subtype-specific dopamine neurons for use in stem cell-based therapies for brain repair in Parkinson’s disease.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Subject classification (UKÄ)
- Medical and Health Sciences
- Basic Medicine
- Neurosciences
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- 1 Similar Profiles
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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TARGET-seq: Linking single-cell transcriptomics of human dopaminergic neurons with their target specificity
Fiorenzano, A., Storm, P., Sozzi, E., Bruzelius, A., Corsi, S., Kajtez, J., Mudannayake, J., Nelander, J., Mattsson, B., Åkerblom, M., Björklund, T., Björklund, A. & Parmar, M., 2024 Nov 19, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 47, p. 1-12 e2410331121.Research output: Contribution to journal › Article › peer-review
Open Access -
Lineage tracing of stem cell-derived dopamine grafts in a Parkinson's model reveals shared origin of all graft-derived cells
Storm, P., Zhang, Y., Nilsson, F., Fiorenzano, A., Krausse, N., Åkerblom, M., Davidsson, M., Yuan, J., Kirkeby, A., Björklund, T. & Parmar, M., 2024 Oct 18, In: Science Advances. 10, 42, p. 1-14 eadn3057.Research output: Contribution to journal › Article › peer-review
Open Access -
3D model for human glia conversion into subtype-specific neurons, including dopamine neurons
Giacomoni, J., Bruzelius, A., Habekost, M., Kajtez, J., Ottosson, D. R., Fiorenzano, A., Storm, P. & Parmar, M., 2024 Sept, In: Cell reports methods. 4, 9, 100845.Research output: Contribution to journal › Article › peer-review
Open Access -
Modular 3D printed platform for fluidically connected human brain organoid culture
Rezaei, B., Giacomoni, J., Nilsson, F., Sozzi, E., Fiorenzano, A., Parmar, M., Keller, S. S. & Kajtez, J., 2024 Jan 1, In: Biofabrication. 1, 15014, 015014.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification and validation of novel engineered AAV capsid variants targeting human glia
Giacomoni, J., Åkerblom, M., Habekost, M., Fiorenzano, A., Kajtez, J., Davidsson, M., Parmar, M. & Björklund, T., 2024, In: Frontiers in Neuroscience. 18, 1435212.Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 2 Active
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Unravelling the molecular basis of sporadic Parkinson's disease in human brain organoids
Fiorenzano, A. (PI)
2024/05/27 → 2025/05/27
Project: Research
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Mapping human dopamine neuron diversity at single-cell resolution for enhanced stem cell therapy in Parkinson's Disease
Fiorenzano, A. (PI)
2023/01/01 → 2027/12/31
Project: Research
Activities
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Neuroscience Day 2022
Pettersson, P. (Organiser), Björklund, A. (Member of programme committee), Ekdahl Clementson, C. (Member of programme committee), Garwicz, M. (Member of programme committee), Magnusson, M. (Member of programme committee), Norrving, B. (Member of programme committee), Parmar, M. (Member of programme committee), Petersén, Å. (Member of programme committee), Hansson, O. (Member of programme committee), COMPAGNO STRANDBERG, M. (Member of programme committee), Gether, U. (Invited speaker), Nieder, A. (Invited speaker), Castelo-Branco, G. (Invited speaker), Cenci Nilsson, A. (Chair), Jakobsson, J. (Chair), Cappello , S. (Invited speaker), Castrén, E. (Keynote/plenary speaker), Garza, R. (Presenter), Salvador, A. (Presenter), Schörling, A. (Presenter), Adami, A. (Presenter), Nilsson, F. (Presenter), Fiorenzano, A. (Presenter), Muralidharan, C. (Presenter), Karlsson, O. (Presenter), Pandiloski, N. (Presenter), Sozzi, E. (Presenter) & Storm, P. (Presenter)
2022 May 5Activity: Participating in or organising an event › Organisation of conference
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Unistem Day 2020
Karlsson, G. (Organiser), Karlsson, C. (Organiser), Pettersson, P. (Organiser), McKay, C. (Organiser), Ahlenius, H. (Organiser), Parmar, M. (Organiser), Magnusson, M. (Organiser), Warfvinge, R. (Organiser), Nolbrant, S. (Speaker), Johansson, P. (Contributor), Atacho, D. (Contributor), Shrigley, S. (Contributor), Jarl, U. (Contributor), Sparrenius, M. (Contributor), Mattsson, B. (Contributor), Hoban, D. (Contributor), Fiorenzano, A. (Contributor), Giacomoni, J. (Contributor), Nilsson, F. (Contributor), Sozzi, E. (Contributor), Hammarberg, A. (Contributor), Pircs, K. (Contributor), Bruzelius, A. (Contributor), Birtele, M. (Contributor), Kidnapillai, S. (Contributor), Cepeda-Prado, E. (Contributor), Mikulik, K. (Contributor), Garza, R. (Contributor) & Storm, P. (Contributor)
2020 Mar 6Activity: Participating in or organising an event › Participation in workshop/ seminar/ course
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Supervision of PhD student: Edoardo Sozzi
Parmar, M. (First/primary/lead supervisor), Ottosson, D. (Joint second supervisor) & Fiorenzano, A. (Joint second supervisor)
2020 → …Activity: Examination and supervision › Supervision of PhD students
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Unistem Day 2019
Parmar, M. (Organiser), Pettersson, P. (Organiser), Shrigley, S. (Contributor), Adler, A. (Contributor), Hoban, D. (Contributor), Sparrenius, M. (Contributor), Fiorenzano, A. (Contributor), Giacomoni, J. (Contributor), Zhang, Y. (Contributor), Grassi, D. (Contributor), Garza, R. (Contributor), Pircs, K. (Contributor), Nolbrant, S. (Contributor), Nilsson, F. (Contributor), Ottosson, D. (Contributor), Birtele, M. (Contributor), Johansson, P. (Contributor), Atacho, D. (Contributor), Jarl, U. (Contributor), Mattsson, B. (Contributor) & Hammarberg, A. (Contributor)
2019 Mar 15Activity: Participating in or organising an event › Organisation of public lecture/debate/seminar