Research output per year
Research output per year
Senior lecturer, Docent
Glioblastoma multiforme (GBM) – the highest-grade glioma and deadliest brain tumor – occurs in pediatric as well as adult patients. Despite aggressive treatment with surgery, irradiation and sometimes chemotherapy, tumors invariably recur as incurable lesions. Tumor cells with stem cell characteristics are thought to be responsible for therapeutic resistance in brain tumors. Despite the crucial role of radiation resistance in patient mortality, few viable therapeutic strategies have been identified to target these resistant cells. Using mouse models of glioma and primary human glioma cultures, we aim to characterize phenotypic intratumoral heterogeneity specifically with regards to radiation resistant stem-like tumor cells, the molecular signaling pathways underlying therapeutic resistance, and microenvironmental control over tumor cell phenotypes with the overall goal of developing novel therapeutic strategies targeting therapy-resistant cells in malignant brain tumors.
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Review article › peer-review
2020/10/01 → …
Project: Dissertation
Pantazopoulou, V. & Pietras, A.
2017/10/01 → 2021/10/29
Project: Dissertation
Göran B Jönsson (Keynote/plenary speaker), Thoas Fioretos (Keynote/plenary speaker), Sophia Zackrisson (Chair), Yvonne Ceder (Chair), Evangelia Sereti (Session chair), Kajsa Paulsson (Speaker), Anna Sandström Gerdtsson (Speaker), Alexander Pietras (Speaker), Sophie Lehn (Session chair), Ervin Ascic (Speaker), Johann de Bono (Keynote/plenary speaker), Daniel Öhlund (Keynote/plenary speaker), luiz diaz (Keynote/plenary speaker), Anna Martner (Keynote/plenary speaker), Gunilla Enblad (Keynote/plenary speaker), Laura J. Esserman (Keynote/plenary speaker), Olli Kallioniemi (Keynote/plenary speaker) & Regina Beets-Tan (Keynote/plenary speaker)
Activity: Participating in or organising an event › Organisation of conference
Alexander Pietras (Organiser), Johan Bengzon (Organiser) & Anna Bång-Rudenstam (Speaker)
Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
Alexander Pietras (Organiser), Johan Bengzon (Organiser) & Henrietta Nittby (Speaker)
Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
Alexander Pietras (Organiser), Johan Bengzon (Organiser) & Pauline Jeannot (Speaker)
Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
Alexander Pietras (Organiser), Johan Bengzon (Organiser), Johan Bengzon (Speaker) & Jason Li (Speaker)
Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course