Research output per year
Research output per year
- 31 results
Search results
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2024
Hypoxia-induced complement component 3 promotes aggressive tumor growth in the glioblastoma microenvironment
Rosberg, R., Smolag, K. I., Sjölund, J., Johansson, E., Bergelin, C., Wahldén, J., Pantazopoulou, V., Ceberg, C., Pietras, K., Blom, A. M. & Pietras, A., 2024 Oct 8, In: JCI Insight. 9, 19, e179854.Research output: Contribution to journal › Article › peer-review
Open Access -
Tumor suppressor role of the complement inhibitor CSMD1 and its role in TNF-induced neuroinflammation in gliomas
Tuysuz, E. C., Mourati, E., Rosberg, R., Moskal, A., Gialeli, C., Johansson, E., Governa, V., Belting, M., Pietras, A. & Blom, A. M., 2024 Apr 1, In: Journal of Experimental and Clinical Cancer Research. 43, p. 1-16 98.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Radiotherapy-induced remodeling of the tumor microenvironment by stromal cells
Berg, T. J. & Pietras, A., 2022 Nov, In: Seminars in Cancer Biology. 86, Part 3, p. 846-856 11 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Special issue: Therapy-induced remodeling of the tumor microenvironment
Pietras, A., 2022 Nov, In: Seminars in Cancer Biology. 86, p. 476Research output: Contribution to journal › Debate/Note/Editorial
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Emerging Roles of DLK1 in the Stem Cell Niche and Cancer Stemness
Grassi, E. S. & Pietras, A., 2022, In: Journal of Histochemistry and Cytochemistry. 70, 1, p. 17-28Research output: Contribution to journal › Review article › peer-review
Open Access -
What (H)IF isoform matters? A deubiquitinase can tune the hypoxic response
Pietras, A., 2022, In: EMBO Journal. 41, 7Research output: Contribution to journal › Debate/Note/Editorial › peer-review
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2021
The Irradiated brain microenvironment supports glioma stemness and survival via astrocyte-derived transglutaminase 2
Berg, T. J., Marques, C., Pantazopoulou, V., Johansson, E., Von Stedingk, K., Lindgren, D., Jeannot, P., Pietras, E. J., Bergström, T., Swartling, F. J., Governa, V., Bengzon, J., Belting, M., Axelson, H., Squatrito, M. & Pietras, A., 2021 Apr 1, In: Cancer Research. 81, 8, p. 2101-2115 15 p.Research output: Contribution to journal › Article › peer-review
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Hypoxia-Induced Reactivity of Tumor-Associated Astrocytes Affects Glioma Cell Properties
Pantazopoulou, V., Jeannot, P., Rosberg, R., Berg, T. J. & Pietras, A., 2021, In: Cells. 10, 3Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Multimodal single-cell analysis reveals distinct radioresistant stem-like and progenitor cell populations in murine glioma
Alexander, J., LaPlant, Q. C., Pattwell, S. S., Szulzewsky, F., Cimino, P. J., Caruso, F. P., Pugliese, P., Chen, Z., Chardon, F., Hill, A. J., Spurrell, C., Ahrendsen, D., Pietras, A., Starita, L. M., Hambardzumyan, D., Iavarone, A., Shendure, J. & Holland, E. C., 2020 Dec, In: GLIA. 68, 12, p. 2486-2502 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma
Grassi, E. S., Pantazopoulou, V. & Pietras, A., 2020 Mar 24, In: Oncogene.Research output: Contribution to journal › Article › peer-review
Open Access -
Niche-derived soluble DLK1 promotes glioma growth
Grassi, E. S., Jeannot, P., Pantazopoulou, V., Berg, T. J. & Pietras, A., 2020, In: Neoplasia (United States). 22, 12, p. 689-701 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2018
The p75 neurotrophin receptor enhances HIF-dependent signaling in glioma
Tong, B., Pantazopoulou, V., Johansson, E. & Pietras, A., 2018 Oct 1, In: Experimental Cell Research. 371, 1, p. 122-129 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
No reason to reconsider HIF-2 as an oncogene in neuroblastoma and other cancer forms
Mohlin, S., Von Stedingk, K., Pietras, A. & Påhlman, S., 2017 Dec 19, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 51, p. E10856-E10858Research output: Contribution to journal › Letter › peer-review
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CD44 interacts with HIF-2α to modulate the hypoxic phenotype of perinecrotic and perivascular glioma cells
Johansson, E., Grassi, E., Pantazopoulou, V., Tong, B., Lindgren, D., Berg, T., Pietras, E., Axelson, H. & Pietras, A., 2017 Aug, In: Cell Reports. 20, 7, p. 1641-1653Research output: Contribution to journal › Article › peer-review
Open Access -
2016
ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells
Wee, B., Pietras, A., Ozawa, T., Bazzoli, E., Podlaha, O., Antczak, C., Westermark, B., Nelander, S., Uhrbom, L., Forsberg-Nilsson, K., Djaballah, H., Michor, F. & Holland, E. C., 2016 Jul 26, In: Scientific Reports. 6, 25956.Research output: Contribution to journal › Article › peer-review
Open Access -
2014
Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth
Pietras, A., Katz, A., Ekström, E., Wee, B., Halliday, J., Pitter, K., Werbeck, J., Amankulor, N., Huse, J. & Holland, E., 2014, In: Cell Stem Cell. 14, 3, p. 357-69Research output: Contribution to journal › Article › peer-review
Open Access -
2012
Tumor-initiating cells in childhood neuroblastoma: Letter
Mohlin, S., Pietras, A., Wigerup, C., Øra, I., Andäng, M., Nilsson, K., Olofsson, T., Gisselsson Nord, D. & Påhlman, S., 2012, In: Cancer Research. 72, 3, p. 821-822Research output: Contribution to journal › Letter › peer-review
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2011
Cancer stem cells in tumor heterogeneity.
Pietras, A., 2011, In: Advances in Cancer Research. 112, p. 255-281Research output: Contribution to journal › Article › peer-review
File391 Downloads (Pure) -
Hunting for Protein Markers of Hypoxia by Combining Plasma Membrane Enrichment with a New Approach to Membrane Protein Analysis
Cifani, P., Bendz, M., Wårell, K., Hansson, K. M., Levander, F., Sandin, M., Krogh, M., Ovenberger, M., Fredlund, E., Vaapil, M., Pietras, A., Påhlman, S. & James, P., 2011, In: Journal of Proteome Research. 10, 4, p. 1645-1656Research output: Contribution to journal › Article › peer-review
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JAG2 induction in hypoxic tumor cells alters Notch signaling and enhances endothelial cell tube formation.
Pietras, A., von Stedingk, K., Lindgren, D., Påhlman, S. & Axelson, H., 2011, In: Molecular Cancer Research. 9, p. 626-636Research output: Contribution to journal › Article › peer-review
File268 Downloads (Pure) -
2010
Hypoxia-Inducible Factors in Tumor Cell Differentiation and Tumor Vascularization
Pietras, A., 2010, Lund University. 136 p.Research output: Thesis › Doctoral Thesis (compilation)
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The HIF-2alpha-Driven Pseudo-Hypoxic Phenotype in Tumor Aggressiveness, Differentiation, and Vascularization.
Pietras, A., Mohlin, S. & Påhlman, S., 2010, Diverse Effects of Hypoxia on Tumor Progression. Celeste Simon, M. (ed.). Springer, Vol. 345. p. 1-20 (Current Topics in Microbiology and Immunology; vol. 345).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
File262 Downloads (Pure) -
2009
Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells.
Pettersson, H., Pietras, A., Thorén, M., Karlsson, J., Johansson, L., Shoshan, M. C. & Påhlman, S., 2009, In: Molecular Cancer Therapeutics. 8, 1, p. 160-170Research output: Contribution to journal › Article › peer-review
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HIF-1{alpha} and HIF-2{alpha} Are Differentially Regulated In vivo in Neuroblastoma: High HIF-1{alpha} Correlates Negatively to Advanced Clinical Stage and Tumor Vascularization.
Noguera, R., Fredlund, E., Piqueras, M., Pietras, A., Beckman, S., Navarro, S. & Påhlman, S., 2009, In: Clinical Cancer Research. 15, 23, p. 7130-7136Research output: Contribution to journal › Article › peer-review
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HIF-2 alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells
Pietras, A., Hansford, L. M., Mohlin, S., Bridges Baxter, E., Sjölund, J., Gisselsson Nord, D., Rehn, M., Beckman, S., Noguera, R., Navarro, S., Cammenga, J., Fredlund, E., Kaplan, D. R. & Påhlman, S., 2009, In: Proceedings of the National Academy of Sciences. 106, 39, p. 16805-16810Research output: Contribution to journal › Article › peer-review
Open Access -
2008
High levels of HIF-2alpha highlight an immature neural crest-like neuroblastoma cell cohort located in a perivascular niche.
Pietras, A., Gisselsson Nord, D., Øra, I., Noguera, R., Beckman, S., Navarro, S. & Påhlman, S., 2008, In: Journal of Pathology. 214, 4, p. 482-488Research output: Contribution to journal › Article › peer-review
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Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo
Sjölund, J., Johansson, M., Manna, S., Norin, C., Pietras, A., Beckman, S., Nilsson, E., Ljungberg, B. & Axelson, H., 2008, In: Journal of Clinical Investigation. 118, 1, p. 217-228Research output: Contribution to journal › Article › peer-review
Open Access -
2007
Arsenic trioxide and neuroblastoma cytotoxicity.
Pettersson, H., Karlsson, J., Pietras, A., Øra, I. & Påhlman, S., 2007, In: Journal of Bioenergetics and Biomembranes. 39, 1, p. 35-41Research output: Contribution to journal › Review article › peer-review
File198 Downloads (Pure) -
Arsenic trioxide-induced neuroblastoma cell death is accompanied by proteolytic activation of nuclear Bax.
Karlsson, J., Pietras, A., Beckman, S., Pettersson, H., Larsson, C. & Påhlman, S., 2007, In: Oncogene. 26, 42, p. 6150-6159Research output: Contribution to journal › Article › peer-review
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Hypoxia inducible factor-2alpha in cancer.
Löfstedt, T., Fredlund, E., Holmquist Mengelbier, L., Pietras, A., Ovenberger, M., Poellinger, L. & Påhlman, S., 2007, In: Cell Cycle. 6, 8, p. 919-926Research output: Contribution to journal › Article › peer-review
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2006
Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype.
Holmquist Mengelbier, L., Fredlund, E., Löfstedt, T., Noguera, R., Navarro, S., Nilsson, H., Pietras, A., Vallon-Christersson, J., Borg, Å., Gradin, K., Poellinger, L. & Påhlman, S., 2006, In: Cancer Cell. 10, 5, p. 413-423Research output: Contribution to journal › Article › peer-review