Personal profile
Research
The focus of my research is identification of tumor biomarkers, addressed through translational projects, in collaboration with clinicians and with concrete clinical needs being tackled through technical approaches. I use machine learning and Spatial Omics for multiplex, spatially-resolved characterization of immune infiltration in solid tumors and lymphomas, with the objective of developing personalized immunotherapeutic treatment strategies. My work on liquid biopsies has involved blood based protein signatures for pancreatic cancer, and single-cell morphometric, proteomic and genomic characterization of circulating tumor cells, in comparison to solid tumors.
Subject classification (UKÄ)
- Medical Biotechnology
- Bioinformatics (Computational Biology)
- Bioinformatics and Computational Biology
- Immunology in the Medical Area (including Cell and Immunotherapy)
- Cell and Molecular Biology
Free keywords
- Immuno-oncology
- Spatial biology
- Image analysis
- Spatial omics
- Tumor microenvironment
- Immunotechnology
- Biomarkers
- Ovarian cancer
- Lung cancer
- Breast cancer
- Multiomics
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations the last five years
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Distinct immune microenvironments in ovarian cancer subtypes indicate potential for immunotherapies
Meldgaard Frank, A., Carlsson, E., Ouyang, H., Olsson, L. M., Mateiou, C., Ek, S., Sundfeldt, K. & Sandström Gerdtsson, A., 2026 Feb 21, In: Journal of Translational Medicine. 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Proteomics discovery of MTDH and SND1 interaction vulnerabilities in ovarian cancer
Esmaeili, P., Nasimian, A., Werner, L., Junior, S. M., Jakobsson, M. E., Gerdtsson, A. S., Kazi, J. U. & Levander, F., 2025 Nov 24, In: Scientific Reports. 15, 1, 41818.Research output: Contribution to journal › Article › peer-review
Open Access -
Altered immune signatures in breast cancer lymph nodes with metastases revealed by spatial proteome analyses
Briem, O., Tahin, B., Frank, A. M., Olsson, L. M., Sandström Gerdtsson, A., Källberg, E. & Leandersson, K., 2025, In: Journal of Translational Medicine. 23, 14 p., 422 (2025).Research output: Contribution to journal › Article › peer-review
Open Access -
The Progression of Mycosis Fungoides During Treatment with Mogamulizumab: A BIO-MUSE Case Study of the Tumor and Immune Response in Peripheral Blood and Tissue
Johansson, A., Kalliara, E., Belfrage, E., Alling, T., Pyl, P. T., Sandström Gerdtsson, A., Gullberg, U., Porwit, A., Drott, K. & Ek, S., 2025, In: Biomedicines. 13, p. 1-29 186.Research output: Contribution to journal › Article › peer-review
Open Access -
Spatial tumor immune microenvironment phenotypes in ovarian cancer
Mateiou, C., Lokhande, L., Diep, L. H., Knulst, M., Carlsson, E., Ek, S., Sundfeldt, K. & Gerdtsson, A., 2024 Dec, In: NPJ precision oncology. 8, 1, 148.Research output: Contribution to journal › Article › peer-review
Open Access
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Investigating STING-directed therapy for ovarian cancer in patient-derived, immune-competent tumor models
Mrs. Berta Kamprad's Cancer Foundation
2026/01/01 → 2027/12/31
Project: Research
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AI-based identification and molecular characterization of prognostic niches in ovarian cancer
2025/05/01 → 2027/04/30
Project: Research
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Spatio-molecular models for profiling ovarian cancer microenvironments
The Royal Physiographic Society in Lund
2024/11/15 → 2026/11/15
Project: Research
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Deep learning from images and spatial omics data for precision immuno-oncology
Crafoord Foundation, Knut and Alice Wallenberg Foundation
2026/06/30 → 2027/06/30
Project: Research
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Molecular Investigations of high-risk Mantle Cell Lymphoma: Genetic Factors and the impact of the microenvironment
de Matos Rodrigues, J. (Researcher), Ek, S. (Supervisor), Jerkeman, M. (Assistant supervisor), Freiburghaus, C. (Assistant supervisor), Sandström Gerdtsson, A. (Assistant supervisor) & Carlsson, A. (Assistant supervisor)
Project: Dissertation
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LUCC - Immunotherapy & tumor microenvironment: Seminar - "Immunotherapy Resistance: Insights, challenges and future directions"
Lundberg, K. (Organiser), Sandström Gerdtsson, A. (Organiser), Woods, N.-B. (Organiser), Shaked, Y. (Invited speaker) & Jönsson, G. B. (Presenter)
2025 Oct 14Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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LUCC - Immunology, tumour microenvironment & metastasis: Retreat
Leandersson, K. (Organiser) & Sandström Gerdtsson, A. (Organiser)
2025 Jan 23 → 2025 Jan 24Activity: Participating in or organising an event › Organisation of conference
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LUCC - Immunology, tumour microenvironment & metastasis: Minisymposium
Leandersson, K. (Organiser), Sandström Gerdtsson, A. (Organiser), Blom, A. (Presenter) & Phung, B. (Presenter)
2024 Nov 8Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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LUCC - Immunology, tumour microenvironment & metastasis Minisymposium
Leandersson, K. (Organiser), Sandström Gerdtsson, A. (Organiser), Rolny, C. (Presenter) & Briem, O. (Presenter)
2024 Sept 27Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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LUCC - Immunology, tumour microenvironment & metastasis: "Cell-based therapies for cancer"
Leandersson, K. (Organiser), Sandström Gerdtsson, A. (Organiser), Falk, A. (Speaker), Ohlin, M. (Speaker), Hyrenius Wittsten, A. (Speaker), Ascic, E. (Speaker) & Woods, N.-B. (Speaker)
2024 Apr 26Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course