Research output per year
Research output per year
Personal profile
Research
Current research interests
Center for primary health care research (CPF) laboratory
CPF experimental research laboratory is part of Center for primary health care research (CPF). It was established with a goal to understand the pathophysiology of common diseases diagnosed in primary health care and to develop diagnostic and prognostic biomarkers for risk assessment and prevention of chronic diseases, commonly diagnosed in primary health care.
Reserach focus
Our focus is mitochondrial genetic and epigenetic changes, their interaction with nuclear genome, and mitochondrial dysfunction in chronic diseases and aging.
The goal of our research is to identify diagnostic and prognostic biomarkers for common chronic diseases such as cardiovascular diseases, cancer, type 2 diabetes mellitus; mental disorders etc. We use clinical samples such as serum/plasma, biopsies and whole blood for analysis and large databases, which include clinical information on patients.
MSc students
We often have thesis projects for Masters students within the projects conducted in our group. Please, contact Ashfaque Memon ([email protected]) or Kristina Sundquist ([email protected]) or Xiao wang ([email protected]) for more details.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
UKÄ subject classification
- Medical and Health Sciences
Free keywords
- Biomarkers
- tumor biology
- DNA
- mutations
- ddPCR
- Circulating tumor DNA
- Venous thromboembolism
- cancer
Fingerprint
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- 1 Similar Profiles
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Effects of a Paleolithic diet compared to a diabetes diet on leptin binding inhibition in secondary analysis of a randomised cross-over study
Fontes-Villalba, M., Granfeldt, Y., Sundquist, K., Memon, A. A., Hedelius, A., Carrera-Bastos, P. & Jönsson, T., 2024 Sept 4, In: BMC Endocrine Disorders. 24, p. 1-7 176.Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondria-DNA copy-number in osteoporosis and osteoarthritis among middle-aged women - A population-based cohort study
Anker-Hansen, C., Pirouzifard, M. N., Memon, A., Sundquist, J., Sundquist, K. & Zöller, B., 2024 Sept, In: Osteoarthritis and Cartilage Open. 6, 3, 100501.Research output: Contribution to journal › Article › peer-review
Open Access -
Hemoglobin homeostasis in abdominal aortic aneurysm: diagnostic and prognostic potential of hemoglobin/heme and scavenger molecules
Vats, S., Sundquist, K., Grundberg, A., Sundquist, J., Wang, X., Zarrouk, M., Gottsäter, A. & Memon, A. A., 2024 Aug 27, In: BMC Cardiovascular Disorders. 24, 1, 452.Research output: Contribution to journal › Article › peer-review
Open Access -
Circulating mitochondrial long non-coding 7S RNA in primary health care patients with depression/anxiety
Wang, X., Memon, A. A., Hedelius, A., Grundberg, A., Sundquist, J. & Sundquist, K., 2024 Mar 15, In: Journal of Affective Disorders. 349, p. 101-106 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Oxidative stress-related genetic variation and antioxidant vitamin intake in intact and ruptured abdominal aortic aneurysm: a Swedish population-based retrospective cohort study
Vats, S., Sundquist, K., Sundquist, J., Zhang, N., Wang, X., Acosta, S., Gottsäter, A. & Memon, A. A., 2024, In: European Journal of Preventive Cardiology. 31, 1, p. 61-74 14 p.Research output: Contribution to journal › Article › peer-review
Open Access
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Genetic and epigenetic changes associated with pathophysiology of abdominal aortic aneurysm
Memon, A. (PI), Gottsäter, A. (CoPI), Vats, S. (Research student) & Sundquist, K. (PI)
2017/11/01 → …
Project: Research
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Circulating DNA as biomarker of early detection and diagnosis of cancer
Memon, A. (PI), Sundquist, K. (PI) & Li, Y. (Research student)
2016/05/01 → …
Project: Research
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VTE: Identification of diagnostic and prognostic biomarkers of venous thromboembolism and its recurrence
Memon, A. (PI) & Svensson, P. (CoPI)
2012/04/02 → …
Project: Research
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Molecular mechanism associated with response to psychotherapeutic interventions in patients with depression/anxiety in primary care patients
Memon, A. (PI), Sundquist, J. (PI) & Wang, X. (Researcher)
2012/03/05 → …
Project: Research
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Finding circulating biomarkers for the detection of early breast cancer
Geukens, C. (Research student), Vats, S. (Assistant supervisor), Li, Y. (Assistant supervisor) & Memon, A. (Supervisor)
2020/11/09 → 2022/06/03
Project: Research
Activities
- 3 Supervision of PhD students
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Role of mitochondria in early molecular diagnosis and prognosis of cancer
Memon, A. (First/primary/lead supervisor), Sundquist, K. (Joint second supervisor) & Wang, X. (Joint second supervisor)
2019 Aug 1 → 2023 Sept 29Activity: Examination and supervision › Supervision of PhD students
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Oxidative stress-related factors in abdominal aortic aneurysm: potential clinical implications
Memon, A. (First/primary/lead supervisor), Gottsäter, A. (Joint second supervisor) & Sundquist, K. (Joint second supervisor)
2017 Nov 1 → 2023 Nov 10Activity: Examination and supervision › Supervision of PhD students
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Identification of genetic biomarkers for the risk prediction of recurrent venous thromboembolism. Risk prediction of recurrent VTE
Memon, A. (First/primary/lead supervisor), Sundquist, K. (Joint second supervisor), Zöller, B. (Joint second supervisor) & Sundquist, J. (Joint second supervisor)
2014 Nov 1 → 2018 Nov 9Activity: Examination and supervision › Supervision of PhD students