Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Axel Hyrenius Wittsten is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases
Thorsson, H., Henningsson, R., Puente-Moncada, N., Peña-Martínez, P., Sjöström, L., Ågerstam, H., Sandén, C., Rissler, M., Castor, A., Marquart, H., Modvig, S., Paulsson, K., Pronk, C. J., Schmiegelow, K., Hyrenius-Wittsten, A., Orsmark-Pietras, C., Lilljebjörn, H. & Fioretos, T., 2024 Sept 26, In: Blood. 144, 13, p. 1399-1411Research output: Contribution to journal › Article › peer-review
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Activating mutations remodel the chromatin accessibility landscape to drive distinct regulatory networks in KMT2A-rearranged acute leukemia
Zhang, Q., Falqués-Costa, T., Pilheden, M., Sturesson, H., Ovlund, T., Rissler, V., Castor, A., Marquart, H. V. H., Lausen, B., Fioretos, T., Hyrenius-Wittsten, A. & Hagström-Andersson, A. K., 2024 Sept, In: HemaSphere. 8, 9, e70006.Research output: Contribution to journal › Article › peer-review
Open Access -
CD4+CAR T-cell exhaustion associated with early relapse of multiple myeloma after BCMA CAR T-cell therapy
Ledergor, G., Fan, Z., Wu, K., McCarthy, E., Hyrenius-Wittsten, A., Starzinski, A., Chang, H., Bridge, M., Kwek, S., Cheung, A., Bylsma, S., Hansen, E., Wolf, J., Wong, S., Shah, N., Roybal, K. T., Martin, T., Ye, C. J. & Fong, L., 2024 Jul, In: Blood Advances. 8, 13, p. 3562-3575 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia
Pilheden, M., Ahlgren, L., Hyrenius-Wittsten, A., Gonzalez-Pena, V., Sturesson, H., Hansen Marquart, H. V., Lausen, B., Castor, A., Pronk, C. J., Barbany, G., Pokrovskaja Tamm, K., Fogelstrand, L., Lohi, O., Norén-Nyström, U., Asklin, J., Chen, Y., Song, G., Walsh, M., Ma, J. & Zhang, J. & 3 others, , 2022 Oct, In: HemaSphere. 6, 10, p. 1-8 e785.Research output: Contribution to journal › Article › peer-review
Open Access -
Modular design of synthetic receptors for programmed gene regulation in cell therapies
Zhu, I., Liu, R., Garcia, J. M., Hyrenius-Wittsten, A., Piraner, D. I., Alavi, J., Israni, D. V., Liu, B., Khalil, A. S. & Roybal, K. T., 2022 Apr, In: Cell. 185, 8, p. 1431-1443.e16Research output: Contribution to journal › Article › peer-review
Projects
- 1 Active
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Enhancing the specificity of cell-based immunotherapy for acute myeloid leukemia
The Swedish Childhood Cancer Fund, Crafoord Foundation, Mats Paulssons stiftelse
2023/06/01 → 2027/05/31
Project: Research
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LUCC - Immunology, tumour microenvironment & metastasis: "Cell-based therapies for cancer"
Leandersson, K. (Organiser), Sandström Gerdtsson, A. (Organiser), Falk, A. (Speaker), Ohlin, M. (Speaker), Hyrenius Wittsten, A. (Speaker), Ascic, E. (Speaker) & Woods, N.-B. (Speaker)
2024 Apr 26Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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Lund University Cancer Centre (LUCC) meeting
Berntsson, P. (Member of programme committee), Zackrisson, S. (Member of programme committee), Nilbert, M. (Member of programme committee), Swaminathan, V. (Member of programme committee), Martling, A. (Invited speaker), Heeren, R. M. A. (Invited speaker), Gisselsson Nord, D. (Speaker), Bellodi, C. (Speaker), Mosquim Junior, S. (Speaker), Andersson, N. (Speaker), Gonçalves de Oliveira, K. (Speaker), Mekuria, S. (Speaker), Helkkula, T. (Speaker), Godina, C. (Speaker), Olsson, L. E. (Speaker), Lång, K. (Speaker), Ågerstam, H. (Speaker), Hyrenius Wittsten, A. (Speaker), Bourgine, P. (Speaker), Alvarado Kristensson, M. (Speaker), Carneiro, A. (Speaker), Jernström, H. (Speaker), Malmborg Kisch, A. (Speaker), Malmström, M. (Speaker), Larsson, A.-M. (Speaker), Zackrisson, S. (Session chair), Paulsson, K. (Session chair), Pronk, K.-J. (Session chair), Swaminathan, V. (Session chair), Hedenfalk, I. (Session chair), Massoumi, R. (Session chair), Dalene Skarping, I. (Session chair), Leandersson, K. (Session chair), Sandström Gerdtsson, A. (Session chair), Järås, M. (Session chair), Carneiro, A. (Session chair), Stocks, T. (Session chair), Malmborg Kisch, A. (Session chair) & Malmström, M. (Session chair)
2023 May 4Activity: Participating in or organising an event › Organisation of conference
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World Cancer Day 2023
Berntsson, P. (Organiser), Jerkeman, M. (Chair), Järås, M. (Chair), Trägårdh, E. (Speaker), Hagström-Andersson, A. (Speaker), Hyrenius Wittsten, A. (Speaker) & Nilsson, M. (Speaker)
2023 Feb 4Activity: Participating in or organising an event › Organisation of conference
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LUCC - Blood, lymphoma & myeloma: Lymphoma – CAR-T in the clinic and in research and future developments - Seminar
Hagström-Andersson, A. (Organiser), Scheding, S. (Organiser), Galeev, R. (Invited speaker) & Hyrenius Wittsten, A. (Speaker)
2023 Jan 26Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course