Research output per year
Research output per year
- 50 - 100 out of 153 results
Search results
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2009
Tiling resolution array-based comparative genomic hybridisation analyses of acute lymphoblastic leukaemias in children with Down syndrome reveal recurrent gain of 8q and deletions of 7p and 9p.
Lundin, C., Davidsson, J., Hjorth, L., Behrendtz, M. & Johansson, B., 2009, In: British Journal of Haematology. 146, p. 113-115Research output: Contribution to journal › Article › peer-review
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2008
BRAF mutations are very rare in B- and T-cell pediatric acute lymphoblastic leukemias.
Davidsson, J., Lilljebjörn, H., Panagopoulos, I., Fioretos, T. & Johansson, B., 2008, In: Leukemia. 22, p. 1619-1621Research output: Contribution to journal › Article › peer-review
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Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: an iBFM-SG study
Forestier, E., Izraeli, S., Beverloo, B., Haas, O., Pession, A., Michalova, K., Stark, B., Harrison, C. J., Teigler-Schlegel, A. & Johansson, B., 2008, In: Blood. 111, 3, p. 1575-1583Research output: Contribution to journal › Article › peer-review
Open Access -
Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression.
Hansson, F., Toporski, J., Månsson, R., Johansson, B., Norén-Nyström, U., Jacobsen, S. E. W., Wiebe, T., Larsson, M., Sigvardsson, M. & Castor, A., 2008, In: Molecular Cancer. 7, 67.Research output: Contribution to journal › Article › peer-review
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FLT3 mutations in a 10 year consecutive series of 177 childhood acute leukemias and their impact on global gene expression patterns.
Andersson, A., Paulsson, K., Lilljebjörn, H., Lassen, C., Strömbeck, B., Heldrup, J., Behrendtz, M., Johansson, B. & Fioretos, T., 2008, In: Genes, Chromosomes and Cancer. 47, p. 64-70Research output: Contribution to journal › Article › peer-review
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Mutations of FLT3, NRAS, KRAS, and PTPN11 are frequent and possibly mutually exclusive in high hyperdiploid childhood acute lymphoblastic leukemia
Paulsson, K., Biloglav, A., Strömbeck, B., Nilsson, F., Heldrup, J., Behrendtz, M., Forestier, E., Andersson, A., Fioretos, T. & Johansson, B., 2008, In: Genes, Chromosomes and Cancer. 47, 1, p. 26-33Research output: Contribution to journal › Article › peer-review
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Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol: frequent late relapses but good overall survival
Forestier, E., Heyman, M., Andersen, M. K., Autio, K., Blennow, E., Borgstrom, G., Golovleva, I., Heim, S., Heinonen, K., Hovland, R., Johannsson, J. H., Kerndrup, G., Nordgren, A., Rosenquist, R., Swolin, B. & Johansson, B., 2008, In: British Journal of Haematology. 140, 6, p. 665-672Research output: Contribution to journal › Article › peer-review
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2007
Characterisation of genomic translocation breakpoints and identification of an alternative TCF3/PBX1 fusion transcript in t(1;19)(q23;p13)-positive acute lymphoblastic leukaemias.
Paulsson, K., Jonson, T., Øra, I., Olofsson, T., Panagopoulos, I. & Johansson, B., 2007, In: British Journal of Haematology. 138, 2, p. 196-201Research output: Contribution to journal › Article › peer-review
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Combined high-resolution array-based comparative genomic hybridization and expression profiling of ETV6/RUNX1-positive acute lymphoblastic leukemias reveal a high incidence of cryptic Xq duplications and identify several putative target genes within the commonly gained region
Lilljebjörn, H., Heidenblad, M., Nilsson, B., Lassen, C., Biloglav, A., Heldrup, J., Behrendtz, M., Johansson, B., Andersson, A. & Fioretos, T., 2007, In: Leukemia. 21, 10, p. 2137-2144Research output: Contribution to journal › Article › peer-review
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Cytogenetic evolution patterns in CML post-SCT.
Karrman, K., Sallerfors, B., Lenhoff, S., Fioretos, T. & Johansson, B., 2007, In: Bone Marrow Transplantation. 39, 3, p. 165-171Research output: Contribution to journal › Article › peer-review
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Fusion gene-mediated truncation of RUNX1 as a potential mechanism underlying disease progression in the 8p11 myeloproliferative syndrome.
Ågerstam, H., Lilljebjörn, H., Lassen, C., Swedin, A., Richter, J., Vandenberghe, P., Johansson, B. & Fioretos, T., 2007, In: Genes, Chromosomes and Cancer. 46, 7, p. 635-643Research output: Contribution to journal › Article › peer-review
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Fusion of NUP98 and the SET binding protein 1 (SETBP1) gene in a paediatric acute T cell lymphoblastic leukaemia with t(11;18)(p15;q12).
Panagopoulos, I., Kerndrup, G., Carlsen, N., Strömbeck, B., Isaksson, M. & Johansson, B., 2007, In: British Journal of Haematology. 136, 2, p. 294-296Research output: Contribution to journal › Article › peer-review
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Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status.
Andersson, A., Ritz, C., Lindgren, D., Edén, P., Lassen, C., Heldrup, J., Olofsson, T., Råde, J., Fontes, M., Porwit-Macdonald, A., Behrendtz, M., Höglund, M., Johansson, B. & Fioretos, T., 2007, In: Leukemia. 21, 6, p. 1198-1203Research output: Contribution to journal › Article › peer-review
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Proposals for standardized Protocols for cytogenetic analyses of acute leukemias, chronic lymphocytic leukemia, chronic myeloid leukemia, chronic myeloproliferative disorders, and myelodysplastic syndromes
Haferlach, C., Rieder, H., Lillington, D. M., Dastugue, N., Hagemeijer, A., Harbott, J., Stilgenbauer, S., Knuutila, S., Johansson, B. & Fonatsch, C., 2007, In: Genes, Chromosomes and Cancer. 46, 5, p. 494-499Research output: Contribution to journal › Article › peer-review
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The molecular signature of MDS stem cells supports a stem-cell origin of 5q - myelodysplastic syndromes
Nilsson, L., Edén, P., Olsson, E., Månsson, R., Åstrand-Grundström, I., Strömbeck, B., Theilgaard-Moench, K., Anderson, K., Hast, R., Hellström, E., Samuelsson, J., Bergh, G., Nerlov, C., Johansson, B., Sigvardsson, M., Borg, Å. & Jacobsen, S. E. W., 2007, In: Blood. 110, 8, p. 3005-3014Research output: Contribution to journal › Article › peer-review
Open Access -
Tiling resolution array CGH of dic(7;9)(p11 approximately 13;p11 approximately 13) in B-cell precursor acute lymphoblastic leukemia reveals clustered breakpoints at 7p11.2 approximately 12.1 and 9p13.1.
Lundin, C., Heidenblad, M., Strömbeck, B., Borg, Å., Hovland, R., Heim, S. & Johansson, B., 2007, In: Cytogenetic and Genome Research. 118, 1, p. 13-18Research output: Contribution to journal › Article › peer-review
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Tiling resolution array comparative genomic hybridization, expression and methylation analyses of dup(1q) in Burkitt lymphomas and pediatric high hyperdiploid acute lymphoblastic leukemias reveal clustered near-centromeric breakpoints and overexpression of genes in 1q22-32.3
Davidsson, J., Andersson, A., Paulsson, K., Heidenblad, M., Isaksson, M., Borg, Å., Heldrup, J., Behrendtz, M., Panagopoulos, I., Fioretos, T. & Johansson, B., 2007, In: Human Molecular Genetics. 16, 18, p. 2215-2225Research output: Contribution to journal › Article › peer-review
Open Access -
2006
A novel and cytogenetically cryptic t(7;21)(p22;q22) in acute myeloid leukemia results in fusion of RUNX1 with the ubiquitin-specific protease gene USP42
Paulsson, K., Békássy, A., Olofsson, T., Mitelman, F., Johansson, B. & Panagopoulos, I., 2006, In: Leukemia. 20, 2, p. 224-229Research output: Contribution to journal › Article › peer-review
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Antithymocyte globulin and cyclosporine A as combination therapy for low-risk non-sideroblastic myelodysplastic syndromes
Broliden, PA., Dahl, IM., Hast, R., Johansson, B., Juvonen, E., Kjeldsen, L., Porwit-MacDonald, A., Sjoo, M., Tangen, JM., Uggla, B., Oberg, G. & Hellstrom-Lindberg, E., 2006, In: Haematologica. 91, 5, p. 667-670Research output: Contribution to journal › Article › peer-review
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Characterisation of dic(9;20)(p11-13;q11) in childhood B-cell precursor acute lymphoblastic leukaemia by tiling resolution array-based comparative genomic hybridisation reveals clustered breakpoints at 9p13.2 and 20q11.2
Schoumans, J., Johansson, B., Corcoran, M., Kuchinskaya, E., Golovleva, I., Grander, D., Forestier, E., Staaf, J., Borg, Å., Gustafsson, B., Blennow, E. & Nordgren, A., 2006, In: British Journal of Haematology. 135, 4, p. 492-499Research output: Contribution to journal › Article › peer-review
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Deregulation of cyclin D2 by juxtaposition with T-cell receptor alpha/delta locus in t(12;14)(p13;q11)-positive childhood T-cell acute lymphoblastic leukemia.
Karrman, K., Andersson, A., Björgvinsdottir, H., Strömbeck, B., Lassen, C., Olofsson, T., Nguyen-Khac, F., Berger, R., Bernard, O., Fioretos, T. & Johansson, B., 2006, In: European Journal of Haematology. 77, 1, p. 27-34Research output: Contribution to journal › Article › peer-review
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FISH mapping of i(7q) in acute leukemias and myxoid liposarcoma reveals clustered breakpoints in 7p11.2: implications for formation and pathogenetic outcome of the idic(7)(p11.2)
Schaad, K., Strömbeck, B., Mandahl, N., Andersen, M. K., Heim, S., Mertens, F. & Johansson, B., 2006, In: Cytogenetic and Genome Research. 114, 2, p. 126-130 5 p.Research output: Contribution to journal › Article › peer-review
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Fusion of ETV6 with an intronic sequence of the BAZ2A gene in a paediatric pre-B acute lymphoblastic leukaemia with a cryptic chromosome 12 rearrangement.
Panagopoulos, I., Strömbeck, B., Isaksson, M., Heldrup, J., Olofsson, T. & Johansson, B., 2006, In: British Journal of Haematology. 133, 3, p. 270-275Research output: Contribution to journal › Article › peer-review
File134 Downloads (Pure) -
High incidence of the ETV6/RUNX1 fusion gene in paediatric precursor B-cell acute lymphoblastic leukaemias with trisomy 21 as the sole cytogenetic change: a Nordic series of cases diagnosed 1989-2005.
Karrman, K., Forestier, E., Andersen, M. K., Autio, K., Borgstrom, G., Heim, S., Heinonen, K., Hovland, R., Kerndrup, G. & Johansson, B., 2006, In: British Journal of Haematology. 135, 3, p. 352-354Research output: Contribution to journal › Article › peer-review
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High-resolution genome-wide array-based comparative genome hybridization reveals cryptic chromosome changes in AML and MDS cases with trisomy 8 as the sole cytogenetic aberration.
Paulsson, K., Heidenblad, M., Strömbeck, B., Staaf, J., Jönsson, G. B., Borg, Å., Fioretos, T. & Johansson, B., 2006, In: Leukemia. 20, 5, p. 840-846Research output: Contribution to journal › Article › peer-review
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Identification of cryptic aberrations and characterization of translocation breakpoints using array CGH in high hyperdiploid childhood acute lymphoblastic leukemia.
Paulsson, K., Heidenblad, M., Mörse, H., Borg, Å., Fioretos, T. & Johansson, B., 2006, In: Leukemia. 20, 11, p. 2002-2007Research output: Contribution to journal › Article › peer-review
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MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene
Storlazzi, CT., Fioretos, T., Surace, C., Lonoce, A., Mastrorilli, A., Strömbeck, B., D'Addabbo, P., Iacovelli, F., Minervini, C., Aventin, A., Dastugue, N., Fonatsch, C., Hagemeijer, A., Jotterand, M., Muhlematter, D., Lafage-Pochitaloff, M., Nguyen-Khac, F., Schoch, C., Slovak, ML., Smith, A., & 4 others, 2006, In: Human Molecular Genetics. 15, 6, p. 933-942Research output: Contribution to journal › Article › peer-review
Open Access -
Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia
Daskalakis, M., Mauritzson, N., Johansson, B., Bouabdallah, K., Onida, F., Kunzmann, R., Mueller-Berndorff, H., Schmitt-Graeff, A. & Luebbert, M., 2006, In: Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis. 30, 8, p. 1043-1047Research output: Contribution to journal › Article › peer-review
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2005
Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia.
Castor, A., Nilsson, L., Åstrand-Grundström, I., Buitenhuis, M., Ramirez, C., Anderson, K., Strömbeck, B., Garwicz, S., Békássy, A., Schmiegelow, K., Lausen, B., Hokland, P., Lehmann, S., Juliusson, G., Johansson, B. & Jacobsen, S. E. W., 2005, In: Nature Medicine. 11, 6, p. 630-637Research output: Contribution to journal › Article › peer-review
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Evidence for a single-step mechanism in the origin of hyperdiploid childhood acute lymphoblastic leukemia.
Paulsson, K., Mörse, H., Fioretos, T., Behrendtz, M., Strömbeck, B. & Johansson, B., 2005, In: Genes, Chromosomes and Cancer. 44, 2, p. 113-122Research output: Contribution to journal › Article › peer-review
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Formation of der(19)t(1;19)(q23;p13) in acute lymphoblastic leukemia.
Paulsson, K., Biloglav, A., Fioretos, T., Mitelman, F. & Johansson, B., 2005, In: Genes, Chromosomes and Cancer. 42, 2, p. 144-148Research output: Contribution to journal › Article › peer-review
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Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations
Andersson, A., Edén, P., Lindgren, D., Nilsson, J., Lassen, C., Heldrup, J., Fontes, M., Borg, Å., Mitelman, F., Johansson, B., Höglund, M. & Fioretos, T., 2005, In: Leukemia. 19, 6, p. 1042-1050Research output: Contribution to journal › Article › peer-review
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Molecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations.
Andersson, A., Olofsson, T., Lindgren, D., Nilsson, B., Ritz, C., Edén, P., Lassen, C., Råde, J., Fontes, M., Mörse, H., Heldrup, J., Behrendtz, M., Mitelman, F., Höglund, M., Johansson, B. & Fioretos, T., 2005, In: Proceedings of the National Academy of Sciences. 102, 52, p. 19069-19074Research output: Contribution to journal › Article › peer-review
Open Access -
Multicolor fluorescence in situ hybridization characterization of cytogenetically polyclonal hematologic malignancies.
Davidsson, J., Paulsson, K. & Johansson, B., 2005, In: Cancer Genetics and Cytogenetics. 163, 2, p. 180-183Research output: Contribution to journal › Article › peer-review
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Prevalence estimates of recurrent balanced cytogenetic aberrations and gene fusions in unselected patients with neoplastic disorders.
Mitelman, F., Mertens, F. & Johansson, B., 2005, In: Genes, Chromosomes and Cancer. 43, 4, p. 350-366Research output: Contribution to journal › Article › peer-review
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2004
Autologous del(20q)-positive erythroid progenitor cells, re-emerging after DLI treatment of an MDS patient relapsing after allo-SCT, can provide a normal peripheral red blood cell count.
Dykes, J., Lindmark, A., Lenhoff, S., Winqvist, I., Johansson, B., Olofsson, T. & Olsson, M. L., 2004, In: Bone Marrow Transplantation. 33, 5, p. 559-563Research output: Contribution to journal › Article › peer-review
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Clinical impact of internal tandem duplications and activating point mutations in FLT3 in acute myeloid leukemia in elderly patients.
Andersson, A., Johansson, B., Lassen, C., Mitelman, F., Billström, R. & Fioretos, T., 2004, In: European Journal of Haematology. 72, 5, p. 307-313Research output: Contribution to journal › Article › peer-review
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Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer
Mitelman, F., Johansson, B. & Mertens, F., 2004 Apr, In: Nature Genetics. 36, 4, p. 331-334 4 p.Research output: Contribution to journal › Article › peer-review
File303 Downloads (Pure) -
Genome characteristics of primary carcinomas, local recurrences, carcinomatoses, and liver metastases from colorectal cancer patients
Diep, C. B., Teixeira, M. R., Thorstensen, L., Wiig, J. N., Eknaes, M., Nesland, J. M., Giercksky, K-E., Johansson, B. & Lothe, R. A., 2004, In: Molecular Cancer. 3, 6.Research output: Contribution to journal › Article › peer-review
Open Access -
High frequencies of chromosomal aberrations in multiple myeloma and monoclonal gammopathy of undetermined significance in direct chromosome preparation.
Nilsson, T., Lenhoff, S., Rylander, L., Höglund, M., Turesson, I., Mitelman, F., Westin, J. & Johansson, B., 2004, In: British Journal of Haematology. 126, 4, p. 487-494Research output: Contribution to journal › Article › peer-review
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Identification of a commonly amplified 4.3 Mb region with overexpression of the C8FW gene, encoding a phosphoprotein regulated by mitogenic pathways, but not of the MYC gene in MYC-containing double minutes in myeloid malignancies.
Storlazzi, C. T., Fioretos, T., Paulsson, K., Strömbeck, B., Lassen, C., Ahlgren, T., Juliusson, G., Mitelman, F., Rocchi, M. & Johansson, B., 2004, In: Human Molecular Genetics. 13, 14, p. 1479-1485Research output: Contribution to journal › Article › peer-review
Open Access -
MDS/AML-associated cytogenetic abnormalities in multiple myeloma and monoclonal gammopathy of undetermined significance: Evidence for frequent de novo occurrence and multipotent stem cell involvement of del(20q).
Nilsson, T., Nilsson, L., Lenhoff, S., Rylander, L., Åstrand-Grundström, I., Strömbeck, B., Höglund, M., Turesson, I., Westin, J., Mitelman, F., Jacobsen, S. E. W. & Johansson, B., 2004, In: Genes, Chromosomes and Cancer. 41, 3, p. 223-231Research output: Contribution to journal › Article › peer-review
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MLL/GRAF fusion in an infant acute monocytic leukemia (AML M5b) with a cytogenetically cryptic ins(5;11)(q31;q23q23).
Panagopoulos, I., Kitagawa, A., Isaksson, M., Mörse, H., Mitelman, F. & Johansson, B., 2004, In: Genes, Chromosomes and Cancer. 41, 4, p. 400-404Research output: Contribution to journal › Article › peer-review
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Structural integrity and expression of the L3MBTL gene in normal and malignant hematopoietic cells
MacGrogan, D., Kalakonda, N., Alvarez, S., Scandura, JM., Boccuni, P., Johansson, B. & Nimer, SD., 2004, In: Genes, Chromosomes and Cancer. 41, 3, p. 203-213Research output: Contribution to journal › Article › peer-review
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The Breakpoint Region of the Most Common Isochromosome, i(17q), in Human Neoplasia Is Characterized by a Complex Genomic Architecture with Large, Palindromic, Low-Copy Repeats.
Barbouti, A., Stankiewicz, P., Nusbaum, C., Cuomo, C., Cook, A., Höglund, M., Johansson, B., Hagemeijer, A., Park, S-S., Mitelman, F., Lupski, J. R. & Fioretos, T., 2004, In: American Journal of Human Genetics. 74, 1, p. 1-10Research output: Contribution to journal › Article › peer-review
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Tumor karyotype predicts clinical outcome in colorectal cancer patients
Bardi, G., Fenger, C., Johansson, B., Mitelman, F. & Heim, S., 2004, In: Journal of Clinical Oncology. 22, 13, p. 2623-2634Research output: Contribution to journal › Article › peer-review
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2003
A Novel Gene, MSI2, Encoding a Putative RNA-binding Protein Is Recurrently Rearranged at Disease Progression of Chronic Myeloid Leukemia and Forms a Fusion Gene with HOXA9 as a Result of the Cryptic t(7;17)(p15;q23).
Barmpouti, A., Höglund, M., Johansson, B., Lassen, C., Nilsson, P-G., Hagemeijer, A., Mitelman, F. & Fioretos, T., 2003, In: Cancer Research. 63, 6, p. 1202-6Research output: Contribution to journal › Article › peer-review
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A pooled analysis of karyotypic patterns, breakpoints and imbalances in 783 cytogenetically abnormal multiple myelomas reveals frequently involved chromosome segments as well as significant age- and sex-related differences.
Nilsson, T., Höglund, M., Lenhoff, S., Rylander, L., Turesson, I., Westin, J., Mitelman, F. & Johansson, B., 2003, In: British Journal of Haematology. 120, 6, p. 960-969Research output: Contribution to journal › Article › peer-review
File264 Downloads (Pure) -
Clinical and genetic studies of ETV6/ABL1-positive chronic myeloid leukaemia in blast crisis treated with imatinib mesylate.
Barbouti, A., Ahlgren, T., Johansson, B., Höglund, M., Lassen, C., Turesson, I., Mitelman, F. & Fioretos, T., 2003, In: British Journal of Haematology. 122, 1, p. 85-93Research output: Contribution to journal › Article › peer-review
File362 Downloads (Pure) -
Cytogenetic abnormalities in childhood acute myeloid leukaemia: a Nordic series comprising all children enrolled in the NOPHO-93-AML trial between 1993 and 2001.
Forestier, E., Heim, S., Blennow, E., Borgström, G., Holmgren, G., Heinonen, K., Johannsson, J., Kerndrup, G., Andersen, M. K., Lundin, C., Nordgren, A., Rosenquist, R., Swolin, B. & Johansson, B., 2003, In: British Journal of Haematology. 121, 4, p. 566-577Research output: Contribution to journal › Article › peer-review