Research output per year
Research output per year
Personal profile
Research
Genetic variants associated with blood disorders and blood cell formation
We are interested in how genetic variation influence blood cell formation and blood cancer risk. The research group is markedly multi-disciplinary, and comprises 16 members with complementary expertise (clinical, computational, experimental). Our output includes clinically implemented discoveries, and publications in top-tier journals like Nature Genetics, Nature Communications, EMBO Molecular Medicine, and Blood.
UKÄ subject classification
- Cancer and Oncology
- Medical Genetics
- Hematology
- Bioinformatics (Computational Biology)
- Immunology in the medical area
- Cell and Molecular Biology
- Clinical Laboratory Medicine
Keywords
- Hematology
- Genomics
- Computational biology
- Bioinformatics
- Immunology
- Klinisk laboratoriemedicin
- Klinisk immunologi
- Klinisk genetik
- Clinical immunology
- Clinical genetics
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Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.
Swaminathan, B., Thorleifsson, G., Jöud, M., Ali, M., Johnsson, E., Ajore, R., Sulem, P., Halvarsson, B-M., Eyjolfsson, G., Haraldsdottir, V., Hultman, C., Ingelsson, E., Kristinsson, S. Y., Kähler, A. K., Lenhoff, S., Masson, G., Mellqvist, U-H., Månsson, R., Nelander, S., Olafsson, I., & 14 others, 2015, In: Nature Communications. 6, p. 1-8 7213.Research output: Contribution to journal › Article › peer-review
Open AccessFile204 Downloads (Pure) -
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression
Ali, M., Ajore, R., Wihlborg, A. K., Niroula, A., Swaminathan, B., Johnsson, E., Stephens, O. W., Morgan, G., Meissner, T., Turesson, I., Goldschmidt, H., Mellqvist, U. H., Gullberg, U., Hansson, M., Hemminki, K., Nahi, H., Waage, A., Weinhold, N. & Nilsson, B., 2018 Dec 1, In: Nature Communications. 9, 1, 1649.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of sequence variants influencing immunoglobulin levels
Jonsson, S., Sveinbjornsson, G., de Lapuente Portilla, A. L., Swaminathan, B., Plomp, R., Dekkers, G., Ajore, R., Ali, M., Bentlage, A. E. H., Elmér, E., Eyjolfsson, G. I., Gudjonsson, S. A., Gullberg, U., Gylfason, A., Halldorsson, B. V., Hansson, M., Holm, H., Johansson, Å., Johnsson, E., Jonasdottir, A., & 18 others, 2017, In: Nature Genetics. 49, 8, p. 1182-1191Research output: Contribution to journal › Article › peer-review
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Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
Mitchell, J. S., Li, N., Weinhold, N., Försti, A., Ali, M., van Duin, M., Thorleifsson, G., Johnson, D. C., Chen, B., Halvarsson, B-M., Gudbjartsson, D. F., Kuiper, R., Stephens, O. W., Bertsch, U., Broderick, P., Campo, C., Einsele, H., Gregory, W. A., Gullberg, U., Henrion, M., & 38 others, 2016, In: Nature Communications. 7, 12050.Research output: Contribution to journal › Article › peer-review
Open Access -
Robust isolation of malignant plasma cells in multiple myeloma.
Frigyesi, I., Adolfsson, J., Ali, M., Christophersen, M. K., Johnsson, E., Turesson, I., Gullberg, U., Hansson, M. & Nilsson, B., 2014, In: Blood. 123, 9, p. 1336-1340Research output: Contribution to journal › Article › peer-review
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Genetic predisposition for multiple myeloma
Nilsson, B., Pertesi, M., Ajore, R., Wihlborg, A., Duran Lozano, L., Cafaro, C., Johnsson, E., Hansson, M., Halvarsson, B. & Niroula, A.
2011/01/03 → …
Project: Research
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Genetic variation exposes regulators of blood cell formation in vivo in humans
Nilsson, B., Lopez de Lapuente Portilla, A., Wihlborg, A., Ekdahl, L., Cafaro, C., Miharada, N., Hansson, M., Johnsson, E., Ali, Z., Larsson, J., Böiers, C. & Niroula, A.
2018/04/01 → 2023/04/30
Project: Research
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Functional analysis of natural genetic variation in human hematopoiesis
Ali, Z., Lopez de Lapuente Portilla, A. & Nilsson, B.
2018/08/15 → …
Project: Dissertation
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Genetic predisposition to Multiple Myeloma
Duran Lozano, L., Nilsson, B. & Lopez de Lapuente Portilla, A.
2018/03/01 → …
Project: Dissertation
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Genetic Predisposition to Sporadic and Familial Multiple Myeloma
Halvarsson, B., Nilsson, B. & Hansson, M.
Project: Dissertation