Research output per year
Research output per year
Search results
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2023
Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex
Strickson, S., Houslay, K. F., Negri, V. A., Ohne, Y., Ottosson, T., Dodd, R. B., Huntington, C. C., Baker, T., Li, J., Stephenson, K. E., O’Connor, A. J., Sagawe, J. S., Killick, H., Moore, T., Rees, D. G., Koch, S., Sanden, C., Wang, Y., Gubbins, E. & Ghaedi, M. & 8 others, , 2023 Sept 1, In: European Respiratory Journal. 62, 3, 2202210.Research output: Contribution to journal › Article › peer-review
Open Access -
Airway hyperresponsiveness reflects corticosteroid-sensitive mast cell involvement across asthma phenotypes
Hvidtfeldt, M., Sverrild, A., Pulga, A., Frøssing, L., Silberbrandt, A., Hostrup, M., Thomassen, M., Sanden, C., Clausson, C. M., Siddhuraj, P., Bornesund, D., Nieto-Fontarigo, J. J., Uller, L., Erjefält, J. & Porsbjerg, C., 2023, In: Journal of Allergy and Clinical Immunology. 152, 1, p. 107-116.e4Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Diffuse alveolar damage patterns reflect the immunological and molecular heterogeneity in fatal COVID-19
Erjefält, J. S., de Souza Xavier Costa, N., Jönsson, J., Cozzolino, O., Dantas, K. C., Clausson, C. M., Siddhuraj, P., Lindö, C., Alyamani, M., Lombardi, S. C. F. S., Mendroni Júnior, A., Antonangelo, L., Faria, C. S., Duarte-Neto, A. N., de Almeida Monteiro, R. A., Rebello Pinho, J. R., Gomes-Gouvêa, M. S., Verciano Pereira, R., Monteiro, J. S. & Setubal, J. C. & 9 others, , 2022 Sept, In: EBioMedicine. 83, 104229.Research output: Contribution to journal › Article › peer-review
Open Access -
Mucosal cryobiopsies: a new method for studying airway pathology in asthma
Hvidtfeldt, M., Sverrild, A., Pulga, A., Frøssing, L., Silberbrandt, A., Sanden, C., Clausson, C. M., Bornesund, D., Erjefält, J. & Porsbjerg, C., 2022, In: ERJ open research. 8, 1, 00666-2021.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
RORγt inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma
Lamb, D., De Sousa, D., Quast, K., Fundel-Clemens, K., Erjefält, J. S., Sandén, C., Hoffmann, H. J., Kästle, M., Schmid, R., Menden, K. & Delic, D., 2021 Dec 1, In: Respiratory Research. 22, 1, 158.Research output: Contribution to journal › Article › peer-review
Open Access -
Lung Mast Cells Have a High Constitutive Expression of Carboxypeptidase A3 mRNA That Is Independent from Granule-Stored CPA3
Siddhuraj, P., Clausson, C. M., Sanden, C., Alyamani, M., Kadivar, M., Marsal, J., Wallengren, J., Bjermer, L. & Erjefält, J. S., 2021, In: Cells. 10, 2Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Eosinophils, basophils, and type 2 immune microenvironments in COPD-affected lung tissue
Jogdand, P., Siddhuraj, P., Mori, M., Sanden, C., Jönsson, J., Walls, A. F., Kearley, J., Humbles, A. A., Kolbeck, R., Bjermer, L., Newbold, P. & Erjefält, J. S., 2020, In: European Respiratory Journal. 55, 4Research output: Contribution to journal › Article › peer-review
Open Access -
2019
IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation
Allinne, J., Scott, G., Lim, W. K., Birchard, D., Erjefält, J. S., Sandén, C., Ben, L. H., Agrawal, A., Kaur, N., Kim, J. H., Kamat, V., Fury, W., Huang, T., Stahl, N., Yancopoulos, G. D., Murphy, A. J., Sleeman, M. A. & Orengo, J. M., 2019 Dec, In: Journal of Allergy and Clinical Immunology. 144, 6, p. 1624-1637 24 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Human G protein-coupled Receptor 30 (GPR30) is N -glycosylated and N-terminal Domain Asparagine 44 is Required for Receptor Structure and Activity
Gonzalez de Valdivia, E., Sandén, C., Kahn, R., Olde, B. & Leeb-Lundberg, F. L. M., 2019 Feb 13, In: Bioscience Reports. 39, 2, BSR20182436.Research output: Contribution to journal › Article › peer-review
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Bronchoscopic mucosal cryobiopsies as a method for studying airway disease
Hvidtfeldt, M., Pulga, A., Hostrup, M., Sanden, C., Mori, M., Bornesund, D., Larsen, K. R., Erjefält, J. S. & Porsbjerg, C., 2019 Jan, In: Clinical and Experimental Allergy. 49, 1, p. 27-34Research output: Contribution to journal › Article › peer-review
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2018
Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage
Scott, I. C., Majithiya, J. B., Sanden, C., Thornton, P., Sanders, P. N., Moore, T., Guscott, M., Corkill, D. J., Erjefält, J. S. & Cohen, E. S., 2018 Dec 1, In: Scientific Reports. 8, 1, 3363.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Broad Th2 neutralization and anti-inflammatory action of pentosan polysulfate sodium in experimental allergic rhinitis
Sanden, C., Mori, M., Jogdand, P., Jönsson, J., Krishnan, R., Wang, X. & Erjefält, J. S., 2017, In: Immunity, Inflammation and Disease. 5, 3, p. 300-309Research output: Contribution to journal › Article › peer-review
Open Access -
2016
Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs
Silver, J. S., Kearley, J., Copenhaver, A. M., Sanden, C., Mori, M., Yu, L., Pritchard, G. H., Berlin, A. A., Hunter, C. A., Bowler, R., Erjefält, J., Kolbeck, R. & Humbles, A. A., 2016, In: Nature Immunology. 17, 6, p. 626-635Research output: Contribution to journal › Article › peer-review
Open Access -
Neuroblastoma patient-derived orthotopic xenografts reflect the microenvironmental hallmarks of aggressive patient tumours
Braekeveldt, N., Wigerup, C., Tadeo, I., Beckman, S., Sandén, C., Jönsson, J., Erjefält, J. S., Berbegall, A. P., Börjesson, A., Backman, T., Øra, I., Navarro, S., Noguera, R., Gisselsson, D., Påhlman, S. & Bexell, D., 2016, In: Cancer Letters. 375, 2, p. 384-389Research output: Contribution to journal › Article › peer-review
Open Access -
2015
A major population of mucosal memory CD4(+) T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality.
Holmkvist, P., Roepstorff, K., Uronen-Hansson, H., Sandén, C., Gudjonsson, S., Hultman Patschan, O., Grip, O., Marsal, J., Schmidtchen, A., Hornum, L., Erjefält, J., Håkansson, K. & Agace, W., 2015, In: Mucosal Immunology. 8, 3, p. 545-558Research output: Contribution to journal › Article › peer-review
File -
Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection.
Kearley, J., Silver, J. S., Sandén, C., Liu, Z., Berlin, A. A., White, N., Mori, M., Pham, T.-H., Ward, C. K., Criner, G. J., Marchetti, N., Mustelin, T., Erjefält, J., Kolbeck, R. & Humbles, A. A., 2015, In: Immunity. 42, 3, p. 566-579Research output: Contribution to journal › Article › peer-review
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IL-17A is Elevated in End-stage COPD and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis.
Roos, A., Sandén, C., Mori, M., Bjermer, L., Stampfli, M. R. & Erjefält, J., 2015, In: American Journal of Respiratory and Critical Care Medicine. 191, 11, p. 1232-1241Research output: Contribution to journal › Article › peer-review
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Interleukin-17A Promotes Neutrophilia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.
Roos, A., Sethi, S., Nikota, J., Wrona, C. T., Dorrington, M. G., Sandén, C., Bauer, C. M., Shen, P., Bowdish, D., Stevenson, C. S., Erjefält, J. & Stampfli, M. R., 2015, In: American Journal of Respiratory and Critical Care Medicine. 192, 4, p. 428-437Research output: Contribution to journal › Article › peer-review
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2014
Kinin-Stimulated B1 Receptor Signaling Depends on Receptor Endocytosis Whereas B2 Receptor Signaling Does Not.
Enquist, J., Sandén, C., Skröder, C., Mathis, S. A. & Leeb-Lundberg, F., 2014, In: Neurochemical Research. 39, 6, p. 1037-1047Research output: Contribution to journal › Article › peer-review
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2013
Kinin B1 receptor homo-oligomerization is required for receptor trafficking to the cell surface.
Sandén, C. & Leeb-Lundberg, F., 2013, In: International Immunopharmacology. 15, 1, p. 121-128Research output: Contribution to journal › Article › peer-review
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2011
G Protein-Coupled Estrogen Receptor 1 (GPER1)/GPR30 Localizes in the Plasma Membrane and Trafficks Intracellularly on Cytokeratin Intermediate Filaments.
Sandén, C., Broselid, S., Cornmark, L., Andersson, K., Daszkiewicz-Nilsson, J., Mårtensson, U., Olde, B. & Leeb-Lundberg, F., 2011, In: Molecular Pharmacology. 79, 3, p. 400-410Research output: Contribution to journal › Article › peer-review
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2009
Activation of TAFI on the Surface of Streptococcus pyogenes Evokes Inflammatory Reactions by Modulating the Kallikrein/Kinin System
Bengtson, S., Sandén, C., Mörgelin, M., Marx, P., Olin, A., Leeb-Lundberg, F., Meijers, J. C. M. & Herwald, H., 2009, In: Journal of Innate Immunity. 1, 1, p. 18-28Research output: Contribution to journal › Article › peer-review
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2008
Kinin B2 Receptor-Mediated Bradykinin Internalization and Metalloendopeptidase EP24.15-Dependent Intracellular Bradykinin Degradation.
Sandén, C., Enquist, J., Bengtson, S., Herwald, H. & Leeb-Lundberg, F., 2008, In: Journal of Pharmacology and Experimental Therapeutics. 326, 1, p. 24-32Research output: Contribution to journal › Article › peer-review