Research output per year
Research output per year
- 50 - 100 out of 103 results
Search results
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2006
{beta}-Cell Lipases and Insulin Secretion.
Fex, M., Lucas, S., Sörhede Winzell, M., Ahrén, B., Holm, C. & Mulder, H., 2006, In: Diabetes. 55, Suppl 2, p. S24-S31Research output: Contribution to journal › Article › peer-review
Open Access -
Comparison of MS/MS methods for protein identification from 2D-PAGE
Arrigoni, G., Fernandez, C., Holm, C., Scigelova, M. & James, P., 2006, In: Journal of Proteome Research. 5, 9, p. 2294-2300Research output: Contribution to journal › Article › peer-review
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Decrease in intramuscular lipid droplets and translocation of HSL in response to muscle contraction and epinephrine
Prats, C., Donsmark, M., Qvortrup, K., Londos, C., Sztalryd, C., Holm, C., Galbo, H. & Ploug, T., 2006, In: Journal of Lipid Research. 47, 11, p. 2392-2399Research output: Contribution to journal › Article › peer-review
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Glucose-stimulated insulin secretion correlates with beta-cell lipolysis.
Sörhede Winzell, M., Ström, K., Holm, C. & Ahrén, B., 2006, In: Nutrition Metabolism and Cardiovascular Diseases. 16, p. S11-S16Research output: Contribution to journal › Article › peer-review
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Inflammatory response in white adipose tissue in the non-obese hormone-sensitive lipase null mouse model.
Hansson, O., Ström, K., Güner, N., Wierup, N., Sundler, F., Höglund, P. & Holm, C., 2006, In: Journal of Proteome Research. 5, 7, p. 1701-1710Research output: Contribution to journal › Article › peer-review
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The hormone-sensitive lipase C-60G promoter polymorphism is associated with increased waist circumference in normal-weight subjects.
Nilsson, E. A., Johansson, L., Ström, K., Hoffstedt, J., Groop, L., Holm, C. & Ridderstråle, M., 2006, In: International Journal of Obesity. 30, 9, p. 1442-1448Research output: Contribution to journal › Article › peer-review
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2005
Adipocyte lipases and defect of lipolysis in human obesity
Langin, D., Dicker, A., Tavernier, G., Hoffstedt, J., Mairal, A., Ryden, M., Arner, E., Sicard, A., Jenkins, C. M., Viguerie, N., van Harmelen, V., Gross, R. W., Holm, C. & Arner, P., 2005, In: Diabetes. 54, 11, p. 3190-3197Research output: Contribution to journal › Article › peer-review
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Continuous separation of lipid particles from erythrocytes by means of laminar flow and acoustic standing wave forces
Petersson, F., Lenshof, A., Holm, C., Bjursten, H. & Laurell, T., 2005, In: Lab on a Chip. 5, 1, p. 20-22Research output: Contribution to journal › Article › peer-review
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Effect of murine strain on metabolic pathways of glucose production after brief or prolonged fasting
Burgess, SC., Jeffrey, FMH., Storey, C., Milde, A., Hausler, N., Merritt, ME., Mulder, H., Holm, C., Sherry, AD. & Malloy, CR., 2005, In: American Journal of Physiology: Endocrinology and Metabolism. 289, 1, p. E53-E61Research output: Contribution to journal › Article › peer-review
Open Access -
Marked Re-Utilization of Free Fatty Acids During Activated Lipolysis in Human Skeletal Muscle.
Enoksson, S., Hagström-Toft, E., Nordahl, J., Hultenby, K., Pettersson, N., Isaksson, B., Permert, J., Wibom, R., Holm, C., Bolinder, J. & Arner, P., 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 2, p. 1189-1195Research output: Contribution to journal › Article › peer-review
Open Access -
Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice
Hansson, O., Donsmark, M., Ling, C., Nevsten, P., Danfelter, M., Andersen, J. N., Galbo, H. & Holm, C., 2005, In: Journal of Lipid Research. 46, 12, p. 2614-2623Research output: Contribution to journal › Article › peer-review
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2004
Amino-terminal anchored surface display in insect cells and budded baculovirus using the amino-terminal end of neuraminidase.
Borg, J., Nevsten, P., Wallenberg, R., Stenström, M., Cardell, S., Falkenberg, C. & Holm, C., 2004, In: Journal of Biotechnology. 114, 1-2, p. 21-30Research output: Contribution to journal › Article › peer-review
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A novel hormone-sensitive lipase isoform expressed in pancreatic beta -cells.
Lindvall, H., Nevsten, P., Ström, K., Wallenberg, R., Sundler, F., Langin, D., Sörhede Winzell, M. & Holm, C., 2004, In: Journal of Biological Chemistry. 279, 5, p. 3828-3836Research output: Contribution to journal › Article › peer-review
Open Access -
Contractions induce phosphorylation of the AMPK site Ser(565) in hormone-sensitive lipase in muscle
Donsmark, M., Langfort, J., Holm, C., Ploug, T. & Galbo, H., 2004, In: Biochemical and Biophysical Research Communications. 316, 3, p. 867-871Research output: Contribution to journal › Article › peer-review
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Effects of Growth Hormone on the Function of beta-Adrenoceptor Subtypes in Rat Adipocytes.
Yang, S., Mulder, H., Holm, C. & Edén, S., 2004, In: Obesity Research. 12, 2, p. 330-339Research output: Contribution to journal › Article › peer-review
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Hormone-sensitive Lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact.
Fex, M., Olofsson, C. S., Krus, U., Bacos, K., Lindvall, H., Sörhede Winzell, M., Rorsman, P., Holm, C. & Mulder, H., 2004, In: Endocrinology. 145, 8, p. 3746-3753Research output: Contribution to journal › Article › peer-review
Open Access -
Inhibition of lipase activity and lipolysis in rat islets reduces insulin secretion.
Mulder, H., Yang, S., Sörhede Winzell, M., Holm, C. & Ahrén, B., 2004, In: Diabetes. 53, 1, p. 122-128Research output: Contribution to journal › Article › peer-review
Open Access -
Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells.
Olofsson, C., Salehi, A., Holm, C. & Rorsman, P., 2004, In: Journal of Physiology. 557, 3, p. 935-948Research output: Contribution to journal › Article › peer-review
Open Access -
Palmitate Stimulation of Glucagon Secretion in Mouse Pancreatic {alpha}-Cells Results From Activation of L-Type Calcium Channels and Elevation of Cytoplasmic Calcium.
Olofsson, C., Salehi, A., Holm, C. & Rorsman, P., 2004, In: Diabetes. 53, 11, p. 2836-2843Research output: Contribution to journal › Article › peer-review
Open Access -
Particle separation using ultrasound can radically reduce embolic load to brain after cardiac surgery.
Bjursten, H., Holm, C., Lenshof, A., Pettersson, F., Johansson, P. & Laurell, T., 2004, In: Annals of Thoracic Surgery. 78, 5, p. 1572-1578Research output: Contribution to journal › Article › peer-review
Open Access -
Regulation and role of hormone-sensitive lipase in rat skeletal muscle
Donsmark, M., Langfort, J., Holm, C., Ploug, T. & Galbo, H., 2004, In: Proceedings of the Nutrition Society. 63, 2, p. 309-314Research output: Contribution to journal › Article › peer-review
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Separation of lipids from blood utilizing ultrasonic standing waves in microfluidic channels.
Petersson, F., Lenshof, A., Holm, C., Bjursten, H. & Laurell, T., 2004, In: Analyst. 129, 10, p. 938-943Research output: Contribution to journal › Article › peer-review
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The testicular form of hormone-sensitive lipase HSLtes confers rescue of male infertility in HSL-deficient mice
Vallet-Erdtmann, V., Tavernier, G., Contreras, J. A., Mairal, A., Rieu, C., Touzalin, AM., Holm, C., Jegou, B. & Langin, D., 2004, In: Journal of Biological Chemistry. 279, 41, p. 42875-42880Research output: Contribution to journal › Article › peer-review
Open Access -
2003
Contractions activate hormone-sensitive lipase in rat muscle by protein kinase C and mitogen-activated protein kinase
Donsmark, M., Langfort, J., Holm, C., Ploug, T. & Galbo, H., 2003, In: Journal of Physiology. 550, 3, p. 845-854Research output: Contribution to journal › Article › peer-review
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Downregulation of islet hormone-sensitive lipase during long-term high-fat feeding.
Sörhede Winzell, M., Holm, C. & Ahrén, B., 2003, In: Biochemical and Biophysical Research Communications. 304, 2, p. 273-278Research output: Contribution to journal › Article › peer-review
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Hormone-sensitive lipase in skeletal muscle: regulatory mechanisms.
Langfort, J., Donsmark, M., Ploug, T., Holm, C. & Galbo, H., 2003, In: Acta Physiologica Scandinavica. 178, 4, p. 397-403Research output: Contribution to journal › Article › peer-review
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Hormone-sensitive lipase is a cholesterol esterase of the intestinal mucosa
Grober, J., Lucas, S., Sörhede Winzell, M., Zaghini, I., Mairal, A., Contreras, J. A., Besnard, P., Holm, C. & Langin, D., 2003, In: Journal of Biological Chemistry. 278, 8, p. 6510-6515Research output: Contribution to journal › Article › peer-review
Open Access -
Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact.
Mulder, H., Sorhede-Winzell, M., Contreras, J. A., Fex, M., Strom, K., Ploug, T., Galbo, H., Arner, P., Lundberg, C., Sundler, F., Ahrén, B. & Holm, C., 2003, In: Journal of Biological Chemistry. 278, 38, p. 36380-36388Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular mechanisms regulating hormone-sensitive lipase and lipolysis.
Holm, C., 2003, In: Biochemical Society Transactions. 31, Pt 6, p. 1120-1124Research output: Contribution to journal › Article › peer-review
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Mutational analysis of the hormone-sensitive lipase translocation reaction in adipocytes
Su, CL., Sztalryd, C., Contreras, J. A., Holm, C., Kimmel, AR. & Londos, C., 2003, In: Journal of Biological Chemistry. 278, 44, p. 43615-43619Research output: Contribution to journal › Article › peer-review
Open Access -
Pancreatic beta-Cell Lipotoxicity Induced by Overexpression of Hormone-Sensitive Lipase.
Sörhede Winzell, M., Svensson, H., Enerbäck, S., Ravnskjaer, K., Mandrup, S., Esser, V., Arner, P., Alves-Guerra, M-C., Miroux, B., Sundler, F., Ahrén, B. & Holm, C., 2003, In: Diabetes. 52, 8, p. 2057-2065Research output: Contribution to journal › Article › peer-review
Open Access -
Relationship of the Hormone-Sensitive Lipase-Mediated Modulation of Cholesterol Metabolism in Individual Compartments of the Testis to Serum Pituitary Hormone and Testosterone Concentrations in a Seasonal Breeder, the Mink (Mustela vison).
Kabbaj, O., Yoon, S. R., Holm, C., Rose, J., Vitale, M. L. & Pelletier, R. -M., 2003, In: Biology of Reproduction. 68, 3, p. 722-734Research output: Contribution to journal › Article › peer-review
Open Access -
The Presence of a Catalytically Inactive Form of Hormone-Sensitive Lipase Is Associated With Decreased Lipolysis in Abdominal Subcutaneous Adipose Tissue of Obese Subjects.
Ray, H., Beylot, M., Arner, P., Larrouy, D., Langin, D., Holm, C. & Large, V., 2003, In: Diabetes. 52, 6, p. 1417-1422Research output: Contribution to journal › Article › peer-review
Open Access -
2002
A unique defect in the regulation of visceral fat cell lipolysis in the polycystic ovary syndrome as an early link to insulin resistance
Ek, I., Arner, P., Ryden, M., Holm, C., Thorne, A., Hoffstedt, J. & Wahrenberg, H., 2002, In: Diabetes. 51, 2, p. 484-492Research output: Contribution to journal › Article › peer-review
Open Access -
C(2)-ceramide influences the expression and insulin-mediated regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 adipocytes.
Mei, J., Stenson, L., Landström, T., Holm, C., Brindley, D., Manganiello, V. & Degerman, E., 2002, In: Diabetes. 51, 3, p. 631-637Research output: Contribution to journal › Article › peer-review
Open Access -
Characterization of a novel testicular form of human hormone-sensitive lipase
Mairal, A., Melaine, N., Laurell, H., Grober, J., Stenson, L., Guillaudeux, T., Holm, C., Jegou, B. & Langin, D., 2002, In: Biochemical and Biophysical Research Communications. 291, 2, p. 286-290Research output: Contribution to journal › Article › peer-review
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Major gentler differences in the lipolytic capacity of abdominal subcutaneous fat cells in obesity observed before and after long-term weight reduction
Lofgren, P., Hoffstedt, J., Ryden, M., Thorne, A., Holm, C., Wahrenberg, H. & Arner, P., 2002, In: Journal of Clinical Endocrinology and Metabolism. 87, 2, p. 764-771Research output: Contribution to journal › Article › peer-review
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2001
A role for hormone-sensitive lipase in the selective mobilization of adipose tissue fatty acids
Raclot, T., Holm, C. & Langin, D., 2001, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1532, 1-2, p. 88-96Research output: Contribution to journal › Article › peer-review
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Expression, activity, and subcellular localization of testicular hormone-sensitive lipase during postnatal development in the guinea pig
Kabbaj, O., Holm, C., Vitale, M. L. & Pelletier, R. -M., 2001, In: Biology of Reproduction. 65, 2, p. 601-612Research output: Contribution to journal › Article › peer-review
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Fatty acid specificity of hormone-sensitive lipase: implication in the selective hydrolysis of triacylglycerols
Raclot, T., Holm, C. & Langin, D., 2001, In: Journal of Lipid Research. 42, 12, p. 2049-2057Research output: Contribution to journal › Article › peer-review
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Long-term leptin treatment of ob/ob mice improves glucose-induced insulin secretion
Khan, A., Narangoda, S., Ahrén, B., Holm, C., Sundler, F. & Efendic, S., 2001, In: International Journal of Obesity. 25, 6, p. 816-821Research output: Contribution to journal › Article › peer-review
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Overexpression of hormone-sensitive lipase in beta-cells results in blunted glucose stimulated insulin secretion after feeding mice a high-fat diet
Sörhede Winzell, M., Svensson, H., Enerback, S., Ahrén, B. & Holm, C., 2001, In: Diabetologia. 44, Suppl. 1, p. A6-A6Research output: Contribution to journal › Article › peer-review
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Testis hormone-sensitive lipase expression in spermatids is governed by a short promoter in transgenic mice
Blaise, R., Guillaudeux, T., Tavernier, G., Daegelen, D., Evrard, B., Mairal, A., Holm, C., Jegou, B. & Langin, D., 2001, In: Journal of Biological Chemistry. 276, 7, p. 5109-5115Research output: Contribution to journal › Article › peer-review
Open Access -
The effect of exercise training on hormone-sensitive lipase in rat intra-abdominal adipose tissue and muscle
Enevoldsen, L. H., Stallknecht, B., Langfort, J., Petersen, L. N., Holm, C., Ploug, T. & Galbo, H., 2001, In: Journal of Physiology. 536, 3, p. 871-877Research output: Contribution to journal › Article › peer-review
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The expression of hormone-sensitive lipase in clonal beta-cells and rat islets is induced by long-term exposure to high glucose
Winzell, M. S., Svensson, H., Arner, P., Ahren, B. & Holm, C., 2001, In: Diabetes. 50, 10, p. 2225-2230Research output: Contribution to journal › Article › peer-review
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1999
Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells
Mulder, H., Stensson Holst, L., Svensson, H., Degerman, E., Sundler, F., Ahrén, B., Rorsman, P. & Holm, C., 1999, In: Diabetes. 48, 1, p. 228-232Research output: Contribution to journal › Article › peer-review
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1998
Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro
Anthonsen, M. W., Rönnstrand, L., Wernstedt, C., Degerman, E. & Holm, C., 1998, In: Journal of Biological Chemistry. 273, 1, p. 215-221Research output: Contribution to journal › Article › peer-review
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Protein kinase B is expressed in pancreatic beta cells and activated upon stimulation with insulin-like growth factor I
Stenson, L., Mulder, H., Manganiello, V., Sundler, F., Ahrén, B., Holm, C. & Degerman, E., 1998, In: Biochemical and Biophysical Research Communications. 250, 1, p. 181-186Research output: Contribution to journal › Article › peer-review
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1997
[2] Regulation of hormone-sensitive lipase activity in adipose tissue
Holm, C., Langin, D., Manganiello, V., Belfrage, P. & Degerman, E., 1997, In: Methods in Enzymology. 286, p. 45-67Research output: Contribution to journal › Article › peer-review
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Partial purification and identification of hormone-sensitive lipase from chicken adipose tissue
Anthonsen, M. W., Degerman, E. & Holm, C., 1997, In: Biochemical and Biophysical Research Communications. 236, 1, p. 94-99Research output: Contribution to journal › Article › peer-review