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Research

Dr. Charlotte Ling is a Professor at Lund University and a principle investigator of the Epigenetics and Diabetes Unit at Lund University Diabetes Centre (LUDC), Sweden. She obtained her PhD in Endocrinology at University of Gothenburg, Sweden in 2002. After a postdoc at Lund University, where she studied genetics of type 2 diabetes, she dedicated her research to the study of epigenetic mechanisms causing type 2 diabetes and metabolic disease. Her research group has over the last two decades pioneered the field of epigenetics in type 2 diabetes. They have made several groundbreaking discoveries such as genome-wide epigenetic modifications in pancreatic islets, skeletal muscle, adipose tissue and the liver from patients with type 2 diabetes compared with non-diabetic control subjects. Dr. Ling’s research group has also shown that genetic and non-genetic factors such as SNPs, exercise, diet, obesity and age alter the genome-wide epigenetic pattern in human primary tissues for type 2 diabetes. Dr. Ling is frequently invited to write review papers and book chapters and to give lectures (e.g. ADA, IDF, Keystone and Endocrine Society) on the topic ‘Epigenetics in Type 2 Diabetes’. She is still dissecting the impact of epigenetics in the pathogenesis of type 2 diabetes. More recently, she is trying to translate her epigenetic findings to biomarkers and novel therapies for precision medicine to improve prediction, prevention and treatments of type 2 diabetes.  

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Free keywords

  • epigenetics
  • Type 2 diabetes
  • pancreat islets
  • Skeletal muscle
  • liver
  • adipose tissue
  • precision medicine
  • LUDC
  • DNA methylation
  • histone modifications
  • biomarkers
  • pharmacoepigenetics

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Collaborations the last five years

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