Christine Ekdahl Clementson

Search results

• 2024

  Proceedings of the “International Congress on Structural Epilepsy & Symptomatic Seizures” (STESS, Gothenburg, Sweden, 29–31 March 2023)

  Brigo, F., Zelano, J., Abraira, L., Bentes, C., Ekdahl, C. T., Lattanzi, S., Ingvar Lossius, M., Redfors, P., Rouhl, R. P. W., Russo, E., Sander, J. W., Vogrig, A. & Wickström, R., 2024, In: Epilepsy and Behavior. 150, 109538.

  Research output: Contribution to journal › Article
• 2023

  Immune response in blood before and after epileptic and psychogenic non-epileptic seizures

  Ahl, M., Taylor, M. K., Avdic, U., Lundin, A., Andersson, M., Amandusson, Å., Kumlien, E., Compagno Strandberg, M. & Ekdahl, C. T., 2023 Mar, In: Heliyon. 9, 3, e13938.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Psychogenic Non-Epileptic Seizures 100%
  • Seizure 100%
  • Psychogenic Nonepileptic Seizure 100%
  • Interleukin 6 75%
  • Epileptic Seizure 50%

• Reduced epilepsy development in synapsin 2 knockout mice with autistic behavior following early systemic treatment with interleukin-6 receptor antibody

  Bäckström, F., Ahl, M., Wickham, J. & Ekdahl, C. T., 2023, In: Epilepsy Research. 191, 107114.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Behavior (Neuroscience) 100%
  • Seizure 100%
  • Epilepsy 100%
  • Brain 66%
  • Pervasive Developmental Disorder 66%
• 2021

  Brain pathology in focal status epilepticus: evidence from experimental models

  de Curtis, M., Rossetti, A. O., Verde, D. V., van Vliet, E. A. & Ekdahl, C. T., 2021 Dec, In: Neuroscience and Biobehavioral Reviews. 131, p. 834-846 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Brain 100%
  • Status Epilepticus 100%
  • Pathology 100%
  • Seizure 27%
  • Epileptic Seizure 27%

• Inflammatory reaction in the retina after focal non-convulsive status epilepticus in mice investigated with high resolution magnetic resonance and diffusion tensor imaging

  Ahl, M., Lindbäck, U., Chary, K., Shibata, K., Chugh, D., Linden Mickelsson, P., Kettunen, M., COMPAGNO STRANDBERG, MARIA., Englund Johansson, U., Sierra, A. & Ekdahl, C. T., 2021 Jul 24, In: Epilepsy Research. 176, 106730.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Retina 100%
  • Status Epilepticus 100%
  • Diffusion Tensor Imaging 100%
  • Magnetic Resonance Imaging 22%
  • In Vivo 22%
  84 Downloads (Pure)

• Levetiracetam and N-Cadherin Antibody Alleviate Brain Pathology Without Reducing Early Epilepsy Development After Focal Non-convulsive Status Epilepticus in Rats

  Avdic, U., Ahl, M., Andersson, M. & Ekdahl, C. T., 2021, In: Frontiers in Neurology. 12, 630154.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epilepsy 100%
  • Status Epilepticus 100%
  • Seizure 36%
  • Hippocampus 27%
  • Brain 18%
• 2019

  Immune profile in blood following non-convulsive epileptic seizures in rats

  Avdic, U., Ahl, M., Öberg, M. & Ekdahl, C. T., 2019 Jan 1, In: Frontiers in Neurology. 10, JUL, 701.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Status Epilepticus 100%
  • Epileptic Seizure 100%
  • Seizure 27%
  • Blood Proteins 27%
  • Brain 18%

• Physical Activity Reduces Epilepsy Incidence: a Retrospective Cohort Study in Swedish Cross-Country Skiers and an Experimental Study in Seizure-Prone Synapsin II Knockout Mice

  Ahl, M., Avdic, U., Strandberg, M. C., Chugh, D., Andersson, E., Hållmarker, U., James, S., Deierborg, T. & Ekdahl, C. T., 2019, In: Sports Medicine - Open. 5, 1, 52.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epileptic Seizure 100%
  • Experimental Study 100%
  • Retrospective Cohort Study 100%
  • Seizure 100%
  • Epilepsy 100%
• 2018

  Decreased post-synaptic density-95 protein expression on dendrites of newborn neurons following CX3CR1 modulation in the epileptogenic adult rodent brain

  Ali, I., Avdic, U., Chugh, D. & Ekdahl, C. T., 2018 Oct 30, In: Cellular and Molecular Immunology. 15, 4, p. 414-417 4 p.

  Research output: Contribution to journal › Letter › peer-review

• Nonconvulsive status epilepticus in rats leads to brain pathology

  Avdic, U., Ahl, M., Chugh, D., Ali, I., Chary, K., Sierra, A. & Ekdahl, C. T., 2018, In: Epilepsia. 59, 5, p. 945-958

  Research output: Contribution to journal › Article › peer-review

  • Brain 100%
  • Status Epilepticus 100%
  • Hippocampus 60%
  • Seizure 40%
  • Diffusion Tensor Imaging 40%
• 2016

  Immune response in the eye following epileptic seizures

  Ahl, M., Avdic, U., Skoug, C., Ali, I., Chugh, D., Johansson, U. E. & Ekdahl Clementson, C., 2016 Jun 27, In: Journal of Neuroinflammation. 13, 1, 155.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epileptic Seizure 100%
  • Brain 75%
  • Microglia 75%
  • Cell Death 75%
  • Retina 75%
• 2015

  Absence of interleukin-1 receptor 1 increases excitatory and inhibitory scaffolding protein expression and microglial activation in the adult mouse hippocampus.

  Avdic, U., Chugh, D., Osman Hussein, H., Chapman, K., Jackson, J. & Ekdahl Clementson, C., 2015, In: Cellular & Molecular Immunology. 12, 5, p. 645-647

  Research output: Contribution to journal › Article › peer-review

• Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2.

  Chugh, D., Ali, I., Bakochi, A., Bahonjic, E., Etholm, L. & Ekdahl Clementson, C., 2015, In: PLoS ONE. 10, 7, e0132366.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain 100%
  • Epilepsy 20%
  • Interleukin 6 20%
  • Gamma-Aminobutyric Acid 20%
  • Synapse 20%

• Role of fractalkine-CX3CR1 pathway in seizure-induced microglial activation, neurodegeneration, and neuroblast production in the adult rat brain.

  Ali, I., Chugh, D. & Ekdahl Clementson, C., 2015, In: Neurobiology of Disease. 74, p. 194-203

  Research output: Contribution to journal › Article › peer-review

  • Brain 100%
  • Neurodegeneration 100%
  • Seizure 100%
  • Neuroblast 100%
  • Neuron 42%
• 2014

  Altered cognitive performance and synaptic function in the hippocampus of mice lacking C3.

  Perez-Alcazar, M., Daborg, J., Stokowska, A., Wasling, P., Björefeldt, A., Kalm, M., Zetterberg, H., Carlström, K., Blomgren, K., Ekdahl Clementson, C., Hanse, E. & Pekna, M., 2014, In: Experimental Neurology. 253, p. 154-164

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hippocampus 100%
  • Synapse 83%
• 2013

  Brain inflammation induces post-synaptic changes during early synapse formation in adult-born hippocampal neurons.

  Chugh, D., Nilsson, P., Afjei, S. A., Bakochi, A. & Ekdahl Clementson, C., 2013, In: Experimental Neurology. 250, p. 176-188

  Research output: Contribution to journal › Article › peer-review

  File

  • Brain 100%
  • Neuron 100%
  • Synapse 23%
  • Microglia 15%
  • Memory 7%
  225 Downloads (Pure)
• 2012

  Altered synaptic properties during integration of adult-born hippocampal neurons following a seizure insult.

  Jackson, J., Chugh, D., Nilsson, P. H., Wood, J., Carlström, K., Lindvall, O. & Ekdahl Clementson, C., 2012, In: PLoS ONE. 7, 4, e35557.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Neuron 100%
  • Seizure 100%
  • Status Epilepticus 42%
  • Brain 28%
  • Synapse 28%
  228 Downloads (Pure)

• Inhibition of Microglial Activation Protects Hippocampal Neurogenesis and Improves Cognitive Deficits in a Transgenic Mouse Model for Alzheimer's Disease

  Biscaro, B., Lindvall, O., Tesco, G., Ekdahl Clementson, C. & Nitsch, R. M., 2012, In: Neurodegenerative Diseases. 9, 4, p. 187-198

  Research output: Contribution to journal › Article › peer-review

  • Cognitive Disorders 100%
  • Beta Amyloid 100%
  • Minocycline 66%
  • Microglia 57%
  • Presenilin 1 33%

• Microglial activation - tuning and pruning adult neurogenesis.

  Ekdahl Clementson, C., 2012, In: Frontiers in Pharmacology. 3, 41, p. 1-9

  Research output: Contribution to journal › Article › peer-review

  File

  • Microglia 100%
  • Neuron 83%
  • Brain 50%
  • Neurodegenerative Disorder 16%
  • Hippocampus 16%
  287 Downloads (Pure)
• 2011

  Functional integration of new hippocampal neurons following insults to the adult brain is determined by characteristics of pathological environment.

  Wood, J., Jackson, J., Jakubs, K., Chapman, K., Ekdahl Clementson, C., Kokaia, Z., Kokaia, M. & Lindvall, O., 2011, In: Experimental Neurology. 229, 2, p. 484-493

  Research output: Contribution to journal › Article › peer-review

  File

  • Brain 100%
  • Neuron 100%
  • Seizure 25%
  • Granule Cell 25%
  • Kindling 25%
  214 Downloads (Pure)

• Selective depletion of Mac-1-expressing microglia in rat subventricular zone does not alter neurogenic response early after stroke.

  Heldmann, U., Mine, Y., Kokaia, Z., Ekdahl Clementson, C. & Lindvall, O., 2011, In: Experimental Neurology. 229, p. 391-398

  Research output: Contribution to journal › Article › peer-review

  File

  • Microglia 100%
  • Stroke 100%
  • Subventricular Zone 100%
  • NADH Dehydrogenase (Ubiquinone) 100%
  • Striatum 30%
  216 Downloads (Pure)
• 2009

  A beta Immunotherapy Protects Morphology and Survival of Adult-Born Neurons in Doubly Transgenic APP/PS1 Mice

  Biscaro, B., Lindvall, O., Hock, C., Ekdahl Clementson, C. & Nitsch, R. M., 2009, In: The Journal of Neuroscience. 29, 45, p. 14108-14119

  Research output: Contribution to journal › Article › peer-review

  • Neuron 100%
  • Hippocampus 33%
  • Brain 22%
  • Alzheimer's Disease 22%
  • Beta Amyloid 22%

• Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke.

  Thored, P., Heldmann, U., Gomes-Leal, W., Gisler, R., Darsalia, V., Taneera, J., Nygren, J., Jacobsen, S. E. W., Ekdahl Clementson, C., Kokaia, Z. & Lindvall, O., 2009, In: GLIA. 57, p. 835-849

  Research output: Contribution to journal › Article › peer-review

  • Microglia 100%
  • Stroke 100%
  • Subventricular Zone 100%
  • Striatum 27%
  • Neural Stem Cell 18%
• 2008

  Inflammation regulates functional integration of neurons born in adult brain.

  Jakubs, K., Bonde, S., Iosif, R., Ekdahl Clementson, C., Kokaia, Z., Kokaia, M. & Lindvall, O., 2008, In: The Journal of Neuroscience : the official journal of the Society for Neuroscience. 28, 47, p. 12477-12488

  Research output: Contribution to journal › Article › peer-review

  • Brain 100%
  • Neuron 100%
  • Microglia 25%
  • Synaptic Plasticity 25%
  • Synapse 25%
• 2007

  Re-evaluation of mitochondrial permeability transition as a primary neuroprotective target of minocycline.

  Månsson, R., Hansson, M., Morota, S., Uchino, H., Ekdahl Clementson, C. & Elmer, E., 2007, In: Neurobiology of Disease. 25, p. 198-205

  Research output: Contribution to journal › Article › peer-review

  File

  • Calcium 100%
  • Animal 25%
  • Human 25%
  • Dose 25%
  • Mitochondrion 25%
  233 Downloads (Pure)
• 2006

  Environment Matters: Synaptic Properties of Neurons Born in the Epileptic Adult Brain Develop to Reduce Excitability.

  Jakubs, K., Nanobashvili, A., Bonde, S., Ekdahl Clementson, C., Kokaia, Z., Kokaia, M. & Lindvall, O., 2006, In: Neuron. 52, 6, p. 1047-1059

  Research output: Contribution to journal › Article › peer-review

  • Brain 100%
  • Neuron 100%
  • Granule Cell 100%
  • Functional Connectivity 25%
  • Neuronal Death 25%

• Long-term neuronal replacement in adult rat hippocampus after status epilepticus despite chronic inflammation.

  Bonde, S., Ekdahl Clementson, C. & Lindvall, O., 2006, In: European Journal of Neuroscience. 23, 4, p. 965-974

  Research output: Contribution to journal › Article › peer-review

• Persistent production of neurons from adult brain stem cells during recovery after stroke.

  Thored, P., Arvidsson, A., Cacci, E., Ahlenius, H., Kallur, T., Darsalia, V., Ekdahl Clementson, C., Kokaia, Z. & Lindvall, O., 2006, In: Stem Cells. 24, 3, p. 739-747

  Research output: Contribution to journal › Article › peer-review

  • Stem Cell 100%
  • Neuron 100%
  • Stroke 100%
  • Brainstem 100%
  • Neural Stem Cell 33%

• Prostaglandin E(2) and BDNF levels in rat hippocampus are negatively correlated with status epilepticus severity: No impact on survival of seizure-generated neurons.

  Ajmone-Cat, M. A., Iosif, R., Ekdahl Clementson, C., Kokaia, Z., Minghetti, L. & Lindvall, O., 2006, In: Neurobiology of Disease. 23, 1, p. 23-35

  Research output: Contribution to journal › Article › peer-review

  • Hippocampus 100%
  • Neuron 100%
  • Seizure 100%
  • Status Epilepticus 100%
  • Cyclooxygenase 25%
• 2004

  Neurogenesis in stroke and epilepsy

  Kokaia, Z., Arvidsson, A., Ekdahl Clementson, C. & Lindvall, O., 2004, Stem Cells in the Nervous System: Functional and Clinical Implications (Research and Perspectives in Neurosciences). Springer, p. 139-146

  Research output: Chapter in Book/Report/Conference proceeding › Paper in conference proceeding › peer-review

  • Neuron 100%
  • Epilepsy 100%
  • Stroke 100%
  • Subventricular Zone 50%
  • Brain 25%

• Status epilepticus severity influences the long-term outcome of neurogenesis in the adult dentate gyrus.

  Mohapel, P., Ekdahl Clementson, C. & Lindvall, O., 2004, In: Neurobiology of Disease. 15, 2, p. 196-205

  Research output: Contribution to journal › Article › peer-review
• 2003

  Death mechanisms compromising hippocampal neurogenesis after status epilepticus

  Ekdahl Clementson, C., 2003, Christine Ekdahl Clementson; [email protected],. 142 p.

  Research output: Thesis › Doctoral Thesis (compilation)

  • Status Epilepticus 100%
  • Neuron 83%
  • Seizure 41%
  • Microglia 33%
  • Cell Death 16%

• Death mechanisms in status epilepticus-generated neurons and effects of additional seizures on their survival.

  Ekdahl Clementson, C., Zhu, C., Bonde, S., Bahr, B. A., Blomgren, K. & Lindvall, O., 2003, In: Neurobiology of Disease. 14, 3, p. 513-523

  Research output: Contribution to journal › Article › peer-review

• Electroconvulsive seizures induce proliferation of NG2-expressing glial cells in adult rat hippocampus.

  Wennström, M., Hellsten, J., Ekdahl Clementson, C. & Tingström, A., 2003, In: Biological Psychiatry. 54, 10, p. 1015-1024

  Research output: Contribution to journal › Article › peer-review

• Inflammation is detrimental for neurogenesis in adult brain.

  Ekdahl Clementson, C., Claasen, J-H., Bonde, S., Kokaia, Z. & Lindvall, O., 2003, In: Proceedings of the National Academy of Sciences. 100, 23, p. 13632-13637

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2002

  Caspase-mediated death of newly formed neurons in the adult rat dentate gyrus following status epilepticus

  Ekdahl, C. T., Mohapel, P., Weber, E., Bahr, B., Blomgren, K. & Lindvall, O., 2002, In: European Journal of Neuroscience. 16, 8, p. 1463-1471 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuron 100%
  • Status Epilepticus 100%
  • Dentate Gyrus 100%
  • Cell Death 33%
  • Calpain 33%

• Electroconvulsive seizures increase hippocampal neurogenesis after chronic corticosterone treatment

  Hellsten, J., Wennström, M., Mohapel, P., Ekdahl, C. T., Bengzon, J. & Tingström, A., 2002, In: European Journal of Neuroscience. 16, 2, p. 283-290 8 p.

  Research output: Contribution to journal › Article › peer-review

  File

  • Seizure 100%
  • Corticosterone 100%
  • Glucocorticoid 57%
  • Broxuridine 57%
  • Neuron Specific Nuclear Protein 42%
  329 Downloads (Pure)

• Neuronal apoptosis after brief and prolonged seizures

  Bengzon, J., Mohapel, P., Ekdahl, C. T. & Lindvall, O., 2002, In: Progress in Brain Research. 135, p. 111-119 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Seizure 100%
  • Cell Death 42%
  • Evoked Seizure 42%
  • Neuron 28%
  • Proteinase 28%
• 2001

  Caspase inhibitors increase short-term survival of progenitor-cell progeny in the adult rat dentate gyrus following status epilepticus

  Ekdahl, C. T., Mohapel, P., Elmer, E. & Lindvall, O., 2001, In: European Journal of Neuroscience. 14, 6, p. 937-945 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Status Epilepticus 100%
  • Dentate Gyrus 100%
  • Neuron 50%
  • Seizure 50%
  • Brain 16%