Christopher Douse

Christopher Douse


Personal profile


My group applies biochemical and functional genomic methods to explore mechanisms underpinning chromatin regulation in stem cell models of the human brain. I am particularly interested in the epigenetic control of repetitive elements, so-called 'genomic dark matter'. 

The big mechanistic questions my lab is currently tackling are:

1. How are repetitive genetic elements regulated by epigenetic mechanisms and chromatin structure?

2. How does this regulatory framework influence human brain evolution, development and degeneration?

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

UKÄ subject classification

  • Medical Genetics

Free keywords

  • Chromatin
  • Epigenetics
  • Transposons
  • Transcription
  • Protein Structure
  • Functional Genomics


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Collaborations the last five years

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