Research output per year
Research output per year
Personal profile
Research
Our research aims at unraveling new post-transcriptional regulatory mechanisms important for the expression of the stem cell genome in physiological and pathological settings. Using the hematopoietic system as a model to study stem cell function, we combine novel genetic approaches with state-of-the-art genome-wide sequencing and proteomic techniques to study central RNA-based regulatory circuitry in hematopoietic stem and cancer cells.
UKÄ subject classification
- Cancer and Oncology
Keywords
- RNA
- Stem cells
- Cancer
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Dive into the research topics where Cristian Bellodi is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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H/ACA small RNA dysfunctions in disease reveal key roles for noncoding RNA modifications in hematopoietic stem cell differentiation
Bellodi, C., McMahon, M., Contreras, A., Juliano, D., Kopmar, N., Nakamura, T., Maltby, D., Burlingame, A., Savage, S. A., Shimamura, A. & Ruggero, D., 2013 May 30, In: Cell Reports. 3, 5, p. 1493-502 10 p.Research output: Contribution to journal › Article › peer-review
Open Access83 Citations (SciVal) -
rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells
Jack, K., Bellodi, C., Landry, D. M., Niederer, R. O., Meskauskas, A., Musalgaonkar, S., Kopmar, N., Krasnykh, O., Dean, A. M., Thompson, S. R., Ruggero, D. & Dinman, J. D., 2011 Nov 18, In: Molecular Cell. 44, 4, p. 660-6 7 p.Research output: Contribution to journal › Article › peer-review
Open Access183 Citations (SciVal) -
Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis
Bellodi, C., Krasnykh, O., Haynes, N., Theodoropoulou, M., Peng, G., Montanaro, L. & Ruggero, D., 2010 Jul 15, In: Cancer Research. 70, 14, p. 6026-35 10 p.Research output: Contribution to journal › Article › peer-review
114 Citations (SciVal) -
Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita
Bellodi, C., Kopmar, N. & Ruggero, D., 2010 Jun 2, In: EMBO Journal. 29, 11, p. 1865-76 12 p.Research output: Contribution to journal › Article › peer-review
Open Access136 Citations (SciVal) -
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells
Bellodi, C., Lidonnici, M. R., Hamilton, A., Helgason, G. V., Soliera, A. R., Ronchetti, M., Galavotti, S., Young, K. W., Selmi, T., Yacobi, R., Van Etten, R. A., Donato, N., Hunter, A., Dinsdale, D., Tirrò, E., Vigneri, P., Nicotera, P., Dyer, M. J., Holyoake, T., Salomoni, P. & 1 others, , 2009 May, In: Journal of Clinical Investigation. 119, 5, p. 1109-23 15 p.Research output: Contribution to journal › Article › peer-review
454 Citations (SciVal)
Activities
- 1 Supervision of PhD students
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Supervision of PhD student: Nejc Arh
Carlos-Filipe Pereira (First/primary/lead supervisor), Cristian Bellodi (Second supervisor) & Anders Wittrup (Second supervisor)
2021 → …Activity: Examination and supervision › Supervision of PhD students