Darcy Wagner

Senior Lecturer, Docent, Wallenberg Molecular Medicine Fellow

  • Phone+46462220839
If you made any changes in Pure these will be visible here soon.

Personal profile

Research

Over three million people die each year and over 60 million people suffer worldwide from chronic lung diseases (CLDs). At present, there is no cure for CLDs, including chronic obstructive pulmonary disease (COPD), pulmonary hypertension, and pulmonary fibrosis. Lung transplantation is the only option at end-stage disease and is further complicated by shortage in organs available for transplantation and low efficacy. Five-year survival rate has remained at 50% for the last decade. New options are desperately needed for these patients.

My lab focuses on understanding the role of the extracellular environment for endogenous and exogenous lung tissue regeneration in healthy and diseased lung. In particular, our work focuses on the design and use of biologic and synthetic scaffolds to bioengineer new lung tissue for transplantation. We further aim to build new models of human lung tissue to reduce animal usage, better understand how regeneration processes are deranged in CLDs, and for use as drug discovery and therapeutic screening platforms.

UKÄ subject classification

  • Cell and Molecular Biology
  • Biomaterials Science
  • Manufacturing, Surface and Joining Technology

Keywords

  • Lung Regeneration
  • Tissue Engineering
  • Stem Cells
  • Biomaterials
  • Mechanotransduction
  • Hippo
  • Bioengineering
  • Ex vivo
  • Bioreactor

Fingerprint

Dive into the research topics where Darcy Wagner is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles

Network

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or