David Borg

2023

An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers

Mezheyeuski, A., Backman, M., Mattsson, J., Martín-Bernabé, A., Larsson, C., Hrynchyk, I., Hammarström, K., Ström, S., Ekström, J., Mauchanski, S., Khelashvili, S., Lindberg, A., Agnarsdóttir, M., Edqvist, P. H., Huvila, J., Segersten, U., Malmström, P-U., Botling, J., Nodin, B., Hedner, C., & 10 othersBorg, D., Brändstedt, J., Sartor, H., Leandersson, K., Glimelius, B., Portyanko, A., Ponten, F., Jirström, K., Micke, P. & Sjöblom, T., 2023, In: EBioMedicine. 88, p. 1-18 104452.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

High infiltration of CD68+/CD163- macrophages is an adverse prognostic factor after neoadjuvant chemotherapy in esophageal and gastric adenocarcinoma

Svensson, M. C., Svensson, M., Nodin, B., Borg, D., Hedner, C., Hjalmarsson, C., Leandersson, K. & Jirström, K., 2022, In: Journal of Innate Immunity. 14, 6 , p. 615-628

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Development of a novel weighted ranking method for immunohistochemical quantification of a heterogeneously expressed protein in gastro-esophageal cancers

Richards, C. E., Sheehan, K. M., Kay, E. W., Hedner, C., Borg, D., Fay, J., O’grady, A., Hill, A. D. K., Jirström, K. & Hopkins, A. M., 2021, In: Cancers. 13, 6, 12 p., 1286.

Research output: Contribution to journal › Article › peer-review

Open Access

T cells, B cells, and PD-L1 expression in esophageal and gastric adenocarcinoma before and after neoadjuvant chemotherapy: relationship with histopathological response and survival

Svensson, M. C., Lindén, A., Nygaard, J., Borg, D., Hedner, C., Nodin, B., Leandersson, K. & Jirström, K., 2021 May 20, In: OncoImmunology. 10, 1, 14 p., 1921443.

Research output: Contribution to journal › Article › peer-review

The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types

Micke, P., Strell, C., Mattsson, J., Martín-Bernabé, A., Brunnström, H., Huvila, J., Sund, M., Wärnberg, F., Ponten, F., Glimelius, B., Hrynchyk, I., Mauchanski, S., Khelashvili, S., Garcia-Vicién, G., Molleví, D. G., Edqvist, P. H., O´Reilly, A., Corvigno, S., Dahlstrand, H., Botling, J., & 17 othersSegersten, U., Krzyzanowska, A., Bjartell, A., Elebro, J., Heby, M., Lundgren, S., Hedner, C., Borg, D., Brändstedt, J., Sartor, H., Malmström, P. U., Johansson, M., Nodin, B., Backman, M., Lindskog, C., Jirström, K. & Mezheyeuski, A., 2021, In: EBioMedicine. 65, 103269.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Palliative short-course hypofractionated radiotherapy followed by chemotherapy in esophageal adenocarcinoma: the phase II PALAESTRA trial

Borg, D., Sundberg, J., Brun, E., Kjellén, E., Petersson, K., Hermansson, M., Johansson, J., Eberhard, J. & Johnsson, A., 2020, In: Acta Oncologica. 59, 2, p. 212-218 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Tumor-Associated CD68⁺, CD163⁺, and MARCO⁺ Macrophages as Prognostic Biomarkers in Patients With Treatment-Naïve Gastroesophageal Adenocarcinoma

Jeremiasen, M., Borg, D., Hedner, C., Svensson, M., Nodin, B., Leandersson, K., Johansson, J. & Jirström, K., 2020 Oct 23, In: Frontiers in Oncology. 10, 534761.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Expression of PD-L1 and PD-1 in chemoradiotherapy-Naïve esophageal and gastric adenocarcinoma: Relationship with mismatch repair status and survival

Svensson, M. C., Borg, D., Zhang, C., Hedner, C., Nodin, B., Uhlén, M., Mardinoglu, A., Leandersson, K. & Jirström, K., 2019 Mar 13, In: Frontiers in Oncology. 9, MAR, 136.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Expression and prognostic significance of human epidermal growth factor receptors 1, 2 and 3 in oesophageal and gastric adenocarcinomas preneoadjuvant and postneoadjuvant treatment

Hedner, C., Borg, D., Nodin, B., Karnevi, E., Jirström, K. & Eberhard, J., 2018 May 1, In: Journal of Clinical Pathology. 71, 5, p. 451-462 12 p.

Research output: Contribution to journal › Article › peer-review

Podocalyxin-like protein as a predictive biomarker for benefit of neoadjuvant chemotherapy in resectable gastric and esophageal adenocarcinoma

Borg, D., Larsson, A. H., Hedner, C., Nodin, B., Johnsson, A. & Jirström, K., 2018, In: Journal of Translational Medicine. 16, 1, 290.

Research output: Contribution to journal › Article › peer-review

Open Access

Prognostic significance of lymphocyte-activation gene-3 expression in chemoradiotherapy-naïve esophageal and gastric adenocarcinoma

Siesing, C., Svensson, M. C., Hedner, C., Nodin, B., Borg, D. & Jirstrom, K., 2018, In: Annals of oncology : official journal of the European Society for Medical Oncology. 29, Suppl. 8, p. viii220

Research output: Contribution to journal › Article › peer-review

Open Access

2017

Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): A multicentre, open-label, randomised, phase 3 trial

Neoptolemos, J. P., Palmer, D. H., Ghaneh, P., Psarelli, E. E., Valle, J. W., Halloran, C. M., Faluyi, O., O'Reilly, D. A., Cunningham, D., Wadsley, J., Darby, S., De Meyer, T., Gillmore, R., Anthoney, A., Lind, P., Glimelius, B., Falk, S., Izbicki, J. R., Middleton, G. W., Cummins, S., & 14 othersRoss, P. J., Wasan, H., McDonald, A., Crosby, T., Ma, Y. T., Patel, K., Sherriff, D., Soomal, R., Borg, D., Sothi, S., Hammel, P., Hackert, T., Jackson, R. & Büchler, M. W., 2017, In: The Lancet. 389, 10073, p. 1011-1024

Research output: Contribution to journal › Article › peer-review

Open Access