David Gisselsson Nord

David Gisselsson Nord

Professor, specialist physician, Senior Consultant Pathologist

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Personal profile

Research

David Gisselsson Nord is a clinician-researcher focused on understanding how cancer cells develop resilience against current ontological treatments. He has identified one of the most common mechanisms by which cancer cells alter their genome through repeated breakage of chromosomes with eroded telomeres. Dr. Gisselsson Nord has also established a series of methods for measuring genetic instability of cancer cells that allow better prediction of prognosis and treatment response. Today he divides his time between clinical work as a pediatric pathologist and research on childhood cancer. His combines high-resolution genomics on clinical samples with mathematical modeling and methods from species evolution. By this approach, his team produces detailed maps of how clones replace each other over space and time, with the main purpose to trace the ancestry of metastatic relapse. Dr. Gisselsson Nord and his team recently identified four fundamental evolutionary trajectories by which cancer cells compete with each other and evolve towards a higher degree of malignancy. He has received the Fernström Prize to Promising Young Investigators and a recent SIOP Award for Translational and Basic research from the International Society of Pediatric Oncology.

Professional work

David Gisselsson Nord is professor of molecular pathology at Lund University and process director for pediatric and fetal pathology in the southern healthcare region of Sweden. He is chair of the national committee for clinical genetic sequencing of childhood tumors, a joint effort between the Swedish Childhood Cancer Fund and Genomic Medicine Sweden. 

 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 5 - Gender Equality

UKÄ subject classification

  • Cancer and Oncology
  • Pediatrics
  • Medical Genetics
  • Evolutionary Biology

Free keywords

  • Pathology
  • Paediatrics
  • Cancer
  • Childhood cancer

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Collaborations and top research areas from the last five years

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