Research output per year
Research output per year
- 45 results
Search results
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2024
Co-delivery of rhBMP-2 and zoledronic acid using calcium sulfate/hydroxyapatite carrier as a bioactive bone substitute to enhance and accelerate spinal fusion
Tian, X., Vater, C., Raina, D. B., Findeisen, L., Matuszewski, L. M., Tägil, M., Lidgren, L., Winkler, A., Gottwald, R., Modler, N., Schaser, K. D., Disch, A. C. & Zwingenberger, S., 2024, In: Bioactive Materials. 36, p. 256-271 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Comparison of immediate anchoring effectiveness of two different techniques of bioresorbable ceramic application for pedicle screw augmentation
Tian, X., Raina, D. B., Oberländer, J. T., Liu, Y., Goronzy, J., Apolle, R., Vater, C., Richter, R. F., Tägil, M., Lidgren, L., Thomas, A., Platz, U., Schaser, K. D., Disch, A. C. & Zwingenberger, S., 2024, (E-pub ahead of print) In: Ceramics International.Research output: Contribution to journal › Article › peer-review
Open Access -
Hydroxyapatite: An Antibiotic Recruiting Moiety for Local Treatment and Prevention of Bone Infections
Sebastian, S., Huang, J., Liu, Y., Tandberg, F., Collin, M., Puthia, M. & Raina, D. B., 2024, In: Journal of Orthopaedic Research. 42, 1, p. 212-222Research output: Contribution to journal › Article › peer-review
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Systemically administered zoledronic acid activates locally implanted synthetic hydroxyapatite particles enhancing peri-implant bone formation: A regenerative medicine approach to improve fracture fixation
Markeviciute, V., Puthia, M., Arvidsson, L., Liu, Y., Törnquist, E., Tengattini, A., Huang, J., Bai, Y., Vater, C., Petrolis, R., Zwingenberger, S., Krisciukaitis, A., Smailys, A., Lukosevicius, S., Stravinskas, M., Isaksson, H., Tarasevicius, S., Lidgren, L., Tägil, M. & Raina, D. B., 2024, (E-pub ahead of print) In: Acta Biomaterialia.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Multi-scale characterization of the spatio-temporal interplay between elemental composition, mineral deposition and remodelling in bone fracture healing
Dejea, H., Raina, D., Silva Barreto, I., Sharma, K., Liu, Y., Ferreira Sanchez, D., Johansson, U. & Isaksson, H., 2023 Sept 1, In: Acta Biomaterialia. 167, p. 135-146 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Sustained delivery of a heterodimer bone morphogenetic protein-2/7 via a collagen hydroxyapatite scaffold accelerates and improves critical femoral defect healing
Liu, Y., Puthia, M., Sheehy, E. J., Ambite, I., Petrlova, J., Prithviraj, S., Oxborg, M. W., Sebastian, S., Vater, C., Zwingenberger, S., Struglics, A., Bourgine, P. E., O'Brien, F. J. & Raina, D. B., 2023 May, In: Acta Biomaterialia. 162, p. 164-181Research output: Contribution to journal › Article › peer-review
Open Access -
A calcium sulphate/hydroxyapatite ceramic biomaterial carrier for local delivery of tobramycin in bone infections: Analysis of rheology, drug release and antimicrobial efficacy
Huang, J., Sebastian, S., Collin, M., Tägil, M., Lidgren, L. & Raina, D. B., 2023, In: Ceramics International. 49, 21, p. 33725-33734Research output: Contribution to journal › Article › peer-review
Open Access -
Bioactive Suture with Added Innate Defense Functionality for the Reduction of Bacterial Infection and Inflammation
Puthia, M., Petrlova, J., Petruk, G., Butrym, M., Samsudin, F., Andersson, M. Å., Strömdahl, A-C., Wasserstrom, S., Hartman, E., Kjellström, S., Caselli, L., Klementieva, O., Bond, P. J., Malmsten, M., Raina, D. & Schmidtchen, A., 2023, In: Advanced healthcare materials. 12, 31Research output: Contribution to journal › Article › peer-review
Open Access -
Systemic rifampicin shows accretion to locally implanted hydroxyapatite particles in a rat abdominal muscle pouch model
Sebastian, S., Huang, J., Liu, Y., Collin, M., Tägil, M., Raina, D. B. & Lidgren, L., 2023, In: Journal of Bone and Joint Infection. 8, 1, p. 19-28Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Evaluation of an Injectable Biphasic Calcium Sulfate/Hydroxyapatite Cement for the Augmentation of Fenestrated Pedicle Screws in Osteoporotic Vertebrae: A Biomechanical Cadaver Study
Tian, X., Raina, D. B., Vater, C., Kilian, D., Ahlfeld, T., Platzek, I., Nimtschke, U., Tägil, M., Lidgren, L., Thomas, A., Platz, U., Schaser, K. D., Disch, A. C. & Zwingenberger, S., 2022 Dec, In: Journal of Functional Biomaterials. 13, 4, 269.Research output: Contribution to journal › Article › peer-review
Open Access -
Longitudinal in vivo biodistribution of nano and micro sized hydroxyapatite particles implanted in a bone defect
Liu, Y., Sebastian, S., Huang, J., Corbascio, T., Engellau, J., Lidgren, L., Tägil, M. & Raina, D. B., 2022 Dec, In: Frontiers in Bioengineering and Biotechnology. 10, 1076320.Research output: Contribution to journal › Article › peer-review
Open Access -
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin
Sebastian, S., Tandberg, F., Liu, Y., Raina, D. B., Tägil, M., Collin, M. & Lidgren, L., 2022 Nov, In: Bone & joint research. 11, 11, p. 787-802 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Fracture behavior of a composite of bone and calcium sulfate/hydroxyapatite
Kok, J., Törnquist, E., Raina, D. B., Le Cann, S., Novak, V., Širka, A., Lidgren, L., Grassi, L. & Isaksson, H., 2022 Jun, In: Journal of the Mechanical Behavior of Biomedical Materials. 130, 9 p., 105201.Research output: Contribution to journal › Article › peer-review
Open Access -
A New Augmentation Method for Improved Screw Fixation in Fragile Bone
Raina, D. B., Markevičiūtė, V., Stravinskas, M., Kok, J., Jacobson, I., Liu, Y., Sezgin, E. A., Isaksson, H., Zwingenberger, S., Tägil, M., Tarasevičius, Š. & Lidgren, L., 2022 Mar, In: Frontiers in Bioengineering and Biotechnology. 10, 816250.Research output: Contribution to journal › Article › peer-review
Open Access -
Bone mineral: A trojan horse for bone cancers. Efficient mitochondria targeted delivery and tumor eradication with nano hydroxyapatite containing doxorubicin
Liu, Y., Nadeem, A., Sebastian, S., Olsson, M. A., Wai, S. N., Styring, E., Engellau, J., Isaksson, H., Tägil, M., Lidgren, L. & Raina, D. B., 2022 Mar, In: Materials Today Bio. 14, 100227.Research output: Contribution to journal › Article › peer-review
Open Access -
Nonionic nontoxic antimicrobial polymers: indole-grafted poly(vinyl alcohol) with pendant alkyl or ether groups
Li, X., İlk, S., Liu, Y., Raina, D. B., Demircan, D. & Zhang, B., 2022, In: Polymer Chemistry. 13, 16, p. 2307-2319 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Sustained and controlled delivery of doxorubicin from an in-situ setting biphasic hydroxyapatite carrier for local treatment of a highly proliferative human osteosarcoma
Liu, Y., Raina, D. B., Sebastian, S., Nagesh, H., Isaksson, H., Engellau, J., Lidgren, L. & Tägil, M., 2021 Sept 1, In: Acta Biomaterialia. 131, p. 555-571 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Dual modality neutron and x-ray tomography for enhanced image analysis of the bone-metal interface
Törnquist, E., Le Cann, S., Tudisco, E., Tengattini, A., And, E., Lenoir, N., Hektor, J., Raina, D. B., Tägil, M., Hall, S. A. & Isaksson, H., 2021 Jul 7, In: Physics in Medicine and Biology. 66, 13, 13 p., 135016.Research output: Contribution to journal › Article › peer-review
Open Access -
Augmenting a dynamic hip screw with a calcium sulfate/hydroxyapatite biomaterial
Kok, J., Širka, A., Liu, Y., Tarasevičius, Š., Belickas, J., Tägil, M., Lidgren, L., Isaksson, H. & Raina, D. B., 2021 Jun, In: Medical Engineering and Physics. 92, p. 102-109 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Synthesis, Enzymatic Degradation, and Polymer-Miscibility Evaluation of Nonionic Antimicrobial Hyperbranched Polyesters with Indole or Isatin Functionalities
Li, X., Ilk, S., Linares-Pastén, J. A., Liu, Y., Raina, D. B., Demircan, D. & Zhang, B., 2021 Apr 26, In: Biomacromolecules. 22, 5, p. 2256 2271 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A combined fracture and mortality risk index useful for treatment stratification in hip fragility fractures
Sezgin, E. A., Tor, A. T., Markevičiūtė, V., Širka, A., Tarasevičius, Š., Raina, D. B., Liu, Y., Isaksson, H., Tägil, M. & Lidgren, L., 2021, In: Joint Diseases and Related Surgery. 32, 3, p. 583-589 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Different microbial and resistance patterns in primary total knee arthroplasty infections – a report on 283 patients from Lithuania and Sweden
Sebastian, S., Sezgin, E. A., Stučinskas, J., Tarasevičius, Š., Liu, Y., Raina, D. B., Tägil, M., Lidgren, L. & W-Dahl, A., 2021, In: BMC Musculoskeletal Disorders. 22, 1, 800.Research output: Contribution to journal › Article › peer-review
Open Access -
Manufacturing of Human Tissues as off-the-Shelf Grafts Programmed to Induce Regeneration
Pigeot, S., Klein, T., Gullotta, F., Dupard, S. J., Garcia Garcia, A., García-García, A., Prithiviraj, S., Lorenzo, P., Filippi, M., Jaquiery, C., Kouba, L., Asnaghi, M. A., Raina, D. B., Dasen, B., Isaksson, H., Önnerfjord, P., Tägil, M., Bondanza, A., Martin, I. & Bourgine, P. E., 2021, In: Advanced Materials. 33, 43, 2103737.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Long-term response to a bioactive biphasic biomaterial in the femoral neck of osteoporotic rats
Raina, D. B., Širka, A., Qayoom, I., Teotia, A. K., Liu, Y., Tarasevicius, S., Tanner, K. E., Isaksson, H., Kumar, A., Tägil, M. & Lidgren, L., 2020 Oct, In: Tissue Engineering - Part A. 26, 19-20, p. 1042-1051 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Longitudinal in vivo monitoring of callus remodeling in BMP-7- and Zoledronate-treated fractures
Mathavan, N., Raina, D. B., Tägil, M. & Isaksson, H., 2020 Sept, In: Journal of Orthopaedic Research. 38, 9, p. 1905-1913 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A biphasic nanohydroxyapatite/calcium sulphate carrier containing Rifampicin and Isoniazid for local delivery gives sustained and effective antibiotic release and prevents biofilm formation
Qayoom, I., Verma, R., Murugan, P. A., Raina, D. B., Teotia, A. K., Matheshwaran, S., Nair, N. N., Tägil, M., Lidgren, L. & Kumar, A., 2020, In: Scientific Reports. 10, 1, 14128.Research output: Contribution to journal › Article › peer-review
Open Access -
A facile one-stage treatment of critical bone defects using a calcium sulfate/hydroxyapatite biomaterial providing spatiotemporal delivery of bone morphogenic protein-2 and zoledronic acid
Raina, D. B., Matuszewski, L. M., Vater, C., Bolte, J., Isaksson, H., Lidgren, L., Tägil, M. & Zwingenberger, S., 2020, In: Science Advances. 6, 48, abc1779.Research output: Contribution to journal › Article › peer-review
Open Access -
Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study
Sezgin, E. A., Markevičiute, V., Širka, A., Tarasevičius, Š., Raina, D. B., Isaksson, H., Tägil, M. & Lidgren, L., 2020, In: Joint Diseases and Related Surgery. 31, 2, p. 163-168 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Recycling implants: a sustainable solution for musculoskeletal research
Lidgren, L., Raina, D. B., Tägil, M. & Tanner, K. E., 2020, In: Acta Orthopaedica. 91, 2, p. 125Research output: Contribution to journal › Article › peer-review
Open Access -
Synthesis and Characterization of a Biocomposite Bone Bandage for Controlled Delivery of Bone-Active Drugs in Fracture Nonunions
Raina, D. B., Glencross, A., Chaher, N., Liu, Y., Lidgren, L., Isaksson, H. & Tägil, M., 2020, In: ACS Biomaterials Science and Engineering. 6, 5, p. 2867-2878 12 p.Research output: Contribution to journal › Article › peer-review
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2019
Synthetic hydroxyapatite: a recruiting platform for biologically active molecules
Raina, D. B., Liu, Y., Isaksson, H., Tägil, M. & Lidgren, L., 2019 Nov 4, In: Acta Orthopaedica. 19, 2Research output: Contribution to journal › Article › peer-review
Open Access -
18 F-fluoride as a prognostic indicator of bone regeneration
Mathavan, N., Koopman, J., Raina, D. B., Turkiewicz, A., Tägil, M. & Isaksson, H., 2019, In: Acta Biomaterialia. 90, p. 403-411Research output: Contribution to journal › Article › peer-review
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Biomodulation of an implant for enhanced bone-implant anchorage
Raina, D. B., Larsson, D., Sezgin, E. A., Isaksson, H., Tägil, M. & Lidgren, L., 2019, In: Acta Biomaterialia. 96, p. 619-630Research output: Contribution to journal › Article › peer-review
Open Access -
Fracture strength of the proximal femur injected with a calcium sulfate/hydroxyapatite bone substitute
Kok, J., Širka, A., Grassi, L., Raina, D. B., Tarasevičius, Š., Tägil, M., Lidgren, L. & Isaksson, H., 2019, In: Clinical Biomechanics. 63, p. 172-178 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile96 Downloads (Pure) -
Guided tissue engineering for healing of cancellous and cortical bone using a combination of biomaterial based scaffolding and local bone active molecule delivery
Raina, D. B., Qayoom, I., Larsson, D., Zheng, M. H., Kumar, A., Isaksson, H., Lidgren, L. & Tägil, M., 2019, In: Biomaterials. 188, p. 38-49 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2018
A ceramic bone substitute containing gentamicin gives good outcome in trochanteric hip fractures treated with dynamic hip screw and in revision of total hip arthroplasty: A case series
Stravinskas, M., Tarasevicius, S., Laukaitis, S., Nilsson, M., Raina, D. B. & Lidgren, L., 2018 Dec 6, In: BMC Musculoskeletal Disorders. 19, 1, p. 438 438.Research output: Contribution to journal › Article › peer-review
Open Access -
Gelatin- hydroxyapatite- calcium sulphate based biomaterial for long term sustained delivery of bone morphogenic protein-2 and zoledronic acid for increased bone formation: In-vitro and in-vivo carrier properties
Raina, D. B., Larsson, D., Mrkonjic, F., Isaksson, H., Kumar, A., Lidgren, L. & Tägil, M., 2018 Feb 28, In: Journal of Controlled Release. 272, p. 83-96 14 p.Research output: Contribution to journal › Article › peer-review
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Calcium Sulphate/Hydroxyapatite Carrier for Bone Formation in the Femoral Neck of Osteoporotic Rats
Širka, A., Raina, D. B., Isaksson, H., Tanner, K. E., Smailys, A., Kumar, A., Tarasevičius, Š., Tägil, M. & Lidgren, L., 2018, In: Tissue Engineering. Part A. 24, 23-24Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Composite biomaterial as a carrier for bone-Active substances for metaphyseal tibial bone defect reconstruction in rats
Horstmann, P. F., Raina, D. B., Isaksson, H., Hettwer, W., Lidgren, L., Petersen, M. M. & Tägil, M., 2017 Dec 1, In: Tissue Engineering - Part A. 23, 23-24, p. 1403-1412 10 p.Research output: Contribution to journal › Article › peer-review
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Nano-Hydroxyapatite Bone Substitute Functionalized with Bone Active Molecules for Enhanced Cranial Bone Regeneration
Teotia, A. K., Raina, D. B., Singh, C., Sinha, N., Isaksson, H., Tägil, M., Lidgren, L. & Kumar, A., 2017 Mar 1, In: ACS Applied Materials and Interfaces. 9, 8, p. 6816-6828 13 p.Research output: Contribution to journal › Article › peer-review
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2016
Biocomposite macroporous cryogels as potential carrier scaffolds for bone active agents augmenting bone regeneration
Raina, D. B., Isaksson, H., Teotia, A. K., Lidgren, L., Tägil, M. & Kumar, A., 2016 Aug 10, In: Journal of Controlled Release. 235, p. 365-378 14 p.Research output: Contribution to journal › Article › peer-review
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A Biphasic Calcium Sulphate/Hydroxyapatite Carrier Containing Bone Morphogenic Protein-2 and Zoledronic Acid Generates Bone
Raina, D. B., Isaksson, H., Hettwer, W., Kumar, A., Lidgren, L. & Tägil, M., 2016 May 18, In: Scientific Reports. 6, 26033.Research output: Contribution to journal › Article › peer-review
Open Access -
Gelatin-Modified Bone Substitute with Bioactive Molecules Enhance Cellular Interactions and Bone Regeneration
Teotia, A. K., Gupta, A., Raina, D. B., Lidgren, L. & Kumar, A., 2016 May 4, In: ACS Applied Materials and Interfaces. 8, 17, p. 10775-10787 13 p.Research output: Contribution to journal › Article › peer-review
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Muscle as an osteoinductive niche for local bone formation with the use of a biphasic calcium sulphate/hydroxyapatite biomaterial
Raina, D. B., Gupta, A., Petersen, M. M., Hettwer, W., McNally, M., Tägil, M., Zheng, M. H., Kumar, A. & Lidgren, L., 2016, In: Bone and Joint Research. 5, 10, p. 500-511 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2015
Study of in Vitro and in Vivo Bone Formation in Composite Cryogels and the Influence of Electrical Stimulation.
Mishra, R., Raina, D., Pelkonen, M., Lidgren, L., Tägil, M. & Kumar, A., 2015, In: International Journal of Biological Sciences. 11, 11, p. 1325-1336Research output: Contribution to journal › Article › peer-review
Open Access