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Einar Sojakka Smith

Einar Sojakka Smith

Affiliated with the university, PhD, M.D

Personal profile

Research

I am an internal-medicine resident and post-doctoral fellow in the Perinatal and Cardiovascular Epidemiology (PACE) group at Lund University, directed by Associate Professor Simon Timpka. Working closely with Associate Professor Sofia Enhörning, I investigate endocrine and hydration-related determinants of cardiometabolic risk. I integrate untargeted and targeted mass-spectrometry metabolomics with longitudinal cohort data and controlled-hydration studies to determine (i) how melatonin secretion modulates glucose homeostasis and (ii) how chronic under-hydration, indexed by vasopressin–copeptin activity, reprograms metabolism and heightens susceptibility to type 2 diabetes and cardiovascular disease.


During my PhD in Professor Olle Melander’s Cardiovascular Research–Hypertension unit, I analysed data from more than 6,000 Malmö-cohort participants and demonstrated that diet-derived metabolic signatures predict atrial fibrillation, type 2 diabetes, cardiovascular events, and mortality. I also showed that a short Mediterranean-style dietary intervention rapidly remodels the circulating metabolome. I now apply the analytical frameworks and nutritional biomarker panels developed in that work to identify modifiable hormonal and hydration targets for the precision prevention of cardiometabolic disorders.

 

I welcome collaborative opportunities that advance this research agenda.

Subject classification (UKÄ)

  • Epidemiology
  • Medical Biostatistics
  • Endocrinology and Diabetes
  • Internal Medicine

Free keywords

  • melatonin
  • diabetes
  • metabolomics

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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Collaborations the last five years

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