Research output per year
Research output per year
Vice-chancellor
Diabetes mellitus is a complex disease caused by an unfavourable combination of inherited traits and environmental factors, mainly those related to our lifestyle. Diabetes is also a multifaceted disorder that should be regarded as an umbrella diagnosis for different diseases with a common major symptom – chronically elevated blood glucose. Common to the absolute majority of disease variants is a reduced capacity for insulin secretion from the beta-cells of the pancreatic islets of Langerhans.
Despite several decades of intense investigations, several of the fundamental reactions of the beta-cell remain elusive. This means that we may misinterpret how diabetes develops and how it should be treated. Development of diabetes is associated with reduced insulin release from the beta-cell, which may dedifferentiate to inactive forms, or even be destroyed by apoptosis. Similar events occur during aging, but elevated concentrations of blood and lipids accelerate this process.
Our research group investigates primarily beta-cells by electrophysiology, live imaging and superresolution microscopy. We have a particular interest in factors that accelerate aging – genetic or environmental - and reactions in the beta-cell that increase the risk of diabetes. Important tools in these endeavors are omics techniques that help us formulate relevant hypotheses.
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Brännstedt, L. (Interviewer) & Renström, E. (Role not specified)
Activity: Talk or presentation › Public lecture/debate/seminar
Gustafsson Lundberg, J. (Role not specified), Maurits, A. (Role not specified), Lindström, F. (Role not specified), Nord, E. (Role not specified), Strannegård, L. (Role not specified) & Renström, E. (Role not specified)
Activity: Talk or presentation › Public lecture/debate/seminar
Wisbrant, J. (Organiser), Åström, K. (Organiser), Aits, S. (Organiser), Larsson, S. (Speaker), Mukhtar-Landgren, D. (Speaker), Güll, M. (Speaker), Åström, K. (Speaker), Lingman, M. (Speaker), Renström, E. (Speaker), Aits, S. (Speaker), Lång, K. (Speaker), Axhamn, J. (Speaker), Felländer, A. (Speaker), Snäll, M. (Speaker) & Lilieqvist, K. (Speaker)
Activity: Participating in or organising an event › Organisation of public lecture/debate/seminar
Larsson, S. (Chair), Wisbrant, J. (Organiser), Åström, K. (Organiser), Aits, S. (Organiser), Lingman, M. (Invited speaker), Renström, E. (Contributor), Mukhtar-Landgren, D. (Invited speaker), Güll, M. (Invited speaker), Felländer, A. (Invited speaker), Axhamn, J. (Invited speaker), Snäll, M. (Participant), Lilieqvist, K. (Presenter) & Lång, K. (Invited speaker)
Activity: Participating in or organising an event › Participation in conference
Östling, J. (Member of panel), Renström, E. (Member of panel), Bäcklund, A.-K. (Member of panel), Wyndhamn, A.-K. (Member of panel) & Ekström, A. (Chair)
Activity: Talk or presentation › Presentation