Frank Wollheim

Search results

• 2002

  Validecoxib - A viewpoint by Frank A. Wollheim

  Wollheim, F., 2002, In: Drugs. 62, 14, p. 2072-2072

  Research output: Contribution to journal › Debate/Note/Editorial
• 2001

  Cytokines, metalloproteinase, their inhibitors, and COMP: relation to radiological progression and inflammation in early rheumatoid arthritis

  Roux-Lombard, P., Eberhardt, K., Saxne, T., Dayer, J.-M. & Wollheim, F., 2001, In: Rheumatology. 40, p. 544-551

  Research output: Contribution to journal › Article › peer-review

• Von Willebrand factor propeptide as a marker of disease activity in systemic sclerosis (scleroderma)

  Scheja, A., Åkesson, A., Geborek, P., Wildt, M., Wollheim, C. B., Wollheim, F. & Vischer, U. M., 2001, In: Arthritis Research & Therapy. 3, 3, p. 178-182

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2000

  Circulating collagen metabolites in systemic sclerosis. Differences between limited and diffuse form and relations to pulmonary involvement

  Scheja, A., Wildt, M., Wollheim, F., Åkesson, A. & Saxne, T., 2000, In: Rheumatology. 39, 10, p. 1110-1113

  Research output: Contribution to journal › Article › peer-review
• 1997

  Cartilage macromolecules and the development of new methods for the assessment of joint disease

  Saxne, T., Wollheim, F. & Heinegård, D., 1997, In: Rheumatology in Europe. 26, p. 108-110

  Research output: Contribution to journal › Article › peer-review

• HLA DRB1* typing and cartilage oligomeric matrix protein as predictors of joint destruction in recent onset rheumatoid arthritis

  Wollheim, F., Eberhardt, K., Johnson, U. & Saxne, T., 1997, In: British Journal of Rheumatology. 36, 8, p. 847-849

  Research output: Contribution to journal › Article › peer-review
• 1996

  Altered dermatan sulfate proteoglycan synthesis in fibroblast cultures established from skin of patients with systemic sclerosis

  Westergren-Thorsson, G., Cöster, L., Akesson, A. & Wollheim, F. A., 1996 Aug, In: Journal of Rheumatology. 23, 8, p. 1398-406

  Research output: Contribution to journal › Article › peer-review

  • Dermatan Sulfate 100%
  • Messenger RNA 57%
  • Metabolic Pathway 28%
  • Decorin 28%
  • Versican 28%

• Computer based quantitative analysis of capillary abnormalities in systemic sclerosis and its relation to plasma concentration of von Willebrand factor

  Scheja, A., Akesson, A., Niewierowicz, I., Wallin, L., Wildt, M. & Wollheim, F. A., 1996 Jan, In: Annals of the Rheumatic Diseases. 55, 1, p. 52-6

  Research output: Contribution to journal › Article › peer-review

  • Blood Level 100%
  • Systemic Scleroderma 100%
  • Quantitative Analysis 100%
  • Patient 37%
  • Density 25%
• 1994

  Prevention of joint destruction in antigen-induced arthritis

  Wollheim, F., Telhag, H., Henricsson, A. & Geborek, P., 1994, In: Clinical Immunology and Immunopathology. 70, 1, p. 19-21

  Research output: Contribution to journal › Article › peer-review

  • Antigen 100%
  • Inflammatory Arthritis 100%
  • Triamcinolone 66%
  • Glucocorticoid 66%
  • Knee 33%
• 1992

  Markers of cartilage destruction. In Rheumatoid Arthritis. Recent Research Advances

  Wollheim, F. & Saxne, T., 1992, Rheumatoid Arthritis. Recent Research Advances. Smolen, J., Kalden, J. & Sir Ravinder, M. (eds.). London: Springer, p. 348-362

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
• 1990

  Intraarticular corticosteroid injection into rheumatoid arthritis knees improves extensor muscles strength

  Geborek, P., Månsson, B., Wollheim, F. & Moritz, U., 1990, In: Rheumatology International. 9, 6, p. 265-270

  Research output: Contribution to journal › Article › peer-review

  • Injection 100%
  • Rheumatoid Arthritis 100%
  • Corticosteroid 100%
  • Extensor Muscle 100%
  • Patient 50%
• 1989

  Direct assessment of synovial blood flow and its relation to induced hydrostatic pressure changes

  Geborek, P., Forslind, K. & Wollheim, F., 1989, In: Annals of the Rheumatic Diseases. 48, 4, p. 281-286

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Blood Flow 100%
  • Hydrostatic Pressure 100%
  • Patient 25%
  • Knee Joint 25%
  • Hypoxia 25%

• Joint capsular stiffness in knee arthritis. Relationship to intraarticular volume, hydrostatic pressures, and extensor muscle function

  Geborek, P., Moritz, U. & Wollheim, F., 1989, In: Journal of Rheumatology. 16, 10, p. 1351-1358

  Research output: Contribution to journal › Article › peer-review

  • Hydrostatic Pressure 100%
  • Knee Joint 66%
  • Patient 33%
  • Therapeutics 33%
  • Awareness 33%

• Synovial fluid acidosis correlates with radiological joint destruction in rheumatoid arthritis knee joints

  Geborek, P., Saxne, T., Pettersson, H. & Wollheim, F., 1989, In: Journal of Rheumatology. 16, 4, p. 468-472

  Research output: Contribution to journal › Article › peer-review

  • Knee Joint 100%
  • Synovial Fluid 100%
  • Rheumatoid Arthritis 100%
  • Acidosis 100%
  • Proteoglycan 40%
• 1988

  Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum.

  Saxne, T., Palladino, M., Heinegård, D., Talal, N. & Wollheim, F., 1988, In: Arthritis and Rheumatism. 31, 8, p. 1041-1045

  Research output: Contribution to journal › Article › peer-review

  • Synovial Fluid 100%
  • Tumor Necrosis Factor 100%
  • Inflammatory Arthritis 100%
  • Tumor Necrosis Factor Alpha 100%
  • Reactive Arthritis 40%

• Human arthritic synovial fluid influences proteoglycan biosynthesis and degradation in organ culture of bovine nasal cartilage.

  Saxne, T., Heinegård, D. & Wollheim, F., 1988, In: Collagen and Related Research. 8, 3, p. 233-247

  Research output: Contribution to journal › Article › peer-review

  • Synovial Fluid 100%
  • Cartilage 100%
  • Biosynthesis 100%
  • Liquid 100%
  • Anabolism 100%

• Measurement of synovial fluid volume using albumin dilution upon intraarticular saline injection

  Geborek, P., Saxne, T., Heinegård, D. & Wollheim, F., 1988, In: Journal of Rheumatology. 15, 1, p. 91-94

  Research output: Contribution to journal › Article › peer-review

• Mononuclear cells recovered from inflammatory synovial membrane using fine-needle biopsy

  Geborek, P., Sandberg Wollheim, M. & Wollheim, F., 1988, In: Rheumatology International. 8, 3, p. 101-105

  Research output: Contribution to journal › Article › peer-review

  • Synovial Membrane 100%
  • Fine-Needle Aspiration 100%
  • Mononuclear Cell 100%
  • Cells 25%
  • Stimulation 25%

• Radiographic assessment in relation to clinical and biochemical variables in rheumatoid arthritis.

  Wollheim, F., Petersson, H., Saxne, T. & Sjöblom, K. G., 1988, In: Scandinavian Journal of Rheumatology. 17, p. 445-453

  Research output: Contribution to journal › Article › peer-review

• Synovial fluid concentrations of interleukin-1 beta and proteoglycans are inversely related.

  Saxne, T., DiGiovine, F., Heinegård, D., Duff, G. & Wollheim, F., 1988, In: Journal of Autoimmunity. 1, p. 373-380

  Research output: Contribution to journal › Article › peer-review
• 1987

  Analysis of homogentisic acid in body fluids by high-performance liquid chromatography

  Akesson, B., Forslind, K. & Wollheim, F., 1987 Jan 23, In: Journal of Chromatography. B. 413, p. 233-6 4 p.

  Research output: Contribution to journal › Article › peer-review

• Cartilage proteoglycans in synovial fluid and serum in patients with inflammatory joint disease. Relation to systemic treatment.

  Saxne, T., Heinegård, D. & Wollheim, F., 1987, In: Arthritis and Rheumatism. 30, 9, p. 972-979

  Research output: Contribution to journal › Article › peer-review

  • Synovial Fluid 100%
  • Cartilage 100%
  • Arthropathy 100%
  • Systemic Treatment 100%
  • Inflammatory Arthritis 60%

• Hyaluronidase treatment of synovial fluid affects the recovery of mononuclear cells and their in vitro immunoglobulin synthesis

  Geborek, P., Truedsson, L., Sandberg Wollheim, M. & Wollheim, F., 1987, In: Clinical and Experimental Rheumatology. 5, 3, p. 255-257

  Research output: Contribution to journal › Article › peer-review

  • Therapeutic Procedure 100%
  • Synovial Fluid 100%
  • In Vitro 100%
  • Cell Population 33%

• Proteoglycan concentration in synovial fluid: predictor of future cartilage destruction in rheumatoid arthritis?

  Saxne, T., Wollheim, F., Petersson, H. & Heinegård, D., 1987, In: BMJ: British Medical Journal. 295, p. 1447-1448

  Research output: Contribution to journal › Article › peer-review
• 1986

  Therapeutic effects on cartilage metabolism in arthritis as measured by release of proteoglycan structures into the synovial fluid.

  Saxne, T., Heinegård, D. & Wollheim, F., 1986, In: Annals of the Rheumatic Diseases. 45, 6, p. 491-497

  Research output: Contribution to journal › Article › peer-review

  • Liquid 100%
  • Metabolic Pathway 100%
  • Therapeutic Effect 100%
  • Reduction (Chemistry) 28%
  • Glucocorticoid 28%
• 1985

  Difference in cartilage proteoglycan level in synovial fluid in early rheumatoid arthritis and reactive arthritis.

  Saxne, T., Heinegård, D., Wollheim, F. & Petersson, H., 1985, In: The Lancet. 2/8447, 8447, p. 127-128

  Research output: Contribution to journal › Article › peer-review

  • Synovial Fluid 100%
  • Cartilage 100%
  • Inflammatory Arthritis 100%
  • Reactive Arthritis 100%
  • Knee 66%
• 1984

  Acute alveolitis and sulphasalazine in rheumatoid arthritis

  Geborek, P., Monti, M., Sandblad, F. & Wollheim, F., 1984, In: Clinical and Experimental Rheumatology. 2, 3, p. 279-280

  Research output: Contribution to journal › Article › peer-review

• Factors related to the progression of joint destruction in rheumatoid arthritis.

  Sjöblom, K. G., Saxne, T., Petersson, H. & Wollheim, F., 1984, In: Scandinavian Journal of Rheumatology. 13, 1, p. 21-27

  Research output: Contribution to journal › Article › peer-review

  • Inflammatory Arthritis 100%
  • Women 75%
  • Male 50%
  • Females 25%
  • Blood Plasma 25%
• 1982

  Preleukemic syndrome simulating SLE

  Saxne, T., Turesson, I. & Wollheim, F., 1982, In: Acta Medica Scandinavica. 212, 6, p. 421-424

  Research output: Contribution to journal › Article › peer-review

  • Therapeutic Procedure 100%
  • Systemic Lupus Erythematosus 100%
  • Syndrome 100%
  • Patient 66%
  • Bone Marrow 66%
• 1980

  Plasma levels of beta-2 microglobulin in rheumatoid arthritis.

  Sjöblom, K. G., Saxne, T. & Wollheim, F., 1980, In: Annals of the Rheumatic Diseases. 39, 4, p. 333-339

  Research output: Contribution to journal › Article › peer-review

  • Inflammatory Arthritis 100%
  • Blood Level 100%
  • Blood Plasma 20%
  • Contrast 20%
  • Creatinine Blood Level 20%