Personal profile
Research
In current molecular cancer research, large scale profiling is typically performed using DNA and RNA measurements. However, proteins are the main machinery of living cells, and proteins undergo post-processing events, which impacts their functionality. Protein profiling could thus improve our understanding of cancer biology. We are using mass spectrometry for protein profiling, and most of our research is dedicated to improving computational methods for processing and analysis of mass spectrometry data, to enable highly resolved, comprehensive measurements. We apply the methods in different collaborative projects with other research groups.
Professional work
Coordinator wihin NBIS (National Bioinformatics Infrastructure). Infrastruture and support.
Group leader in computational proteomics
Subject classification (UKÄ)
- Cancer and Oncology
- Bioinformatics (Computational Biology)
Free keywords
- Proteomics
- Mass spectrometry
- Bioinformatics
- NBIS
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger -
SDG 3 Good Health and Well-being
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Collaborations the last five years
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DIANA - algorithmic improvements for analysis of data-independent acquisition MS data.
Teleman, J., Röst, H., Rosenberger, G., Schmitt, U., Malmström, L., Malmström, J. & Levander, F., 2015, In: Bioinformatics. 31, 4, p. 555-562Research output: Contribution to journal › Article › peer-review
File470 Downloads (Pure) -
Is label-free LC-MS/MS ready for biomarker discovery?
Sandin, M., Chawade, A. & Levander, F., 2015, In: Proteomics Clinical Applications. 9, 3-4, p. 289-294Research output: Contribution to journal › Debate/Note/Editorial › peer-review
File710 Downloads (Pure) -
Normalyzer: A Tool for Rapid Evaluation of Normalization Methods for Omics Data Sets
Chawade, A., Alexandersson, E. & Levander, F., 2014, In: Journal of Proteome Research. 13, 6, p. 3114-3120Research output: Contribution to journal › Article › peer-review
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An adaptive alignment algorithm for quality-controlled label-free LC-MS.
Sandin, M., Ali, A., Hansson, K., Månsson, O., Andreasson, E., Resjö, S. & Levander, F., 2013, In: Molecular & Cellular Proteomics. 12, 5, p. 1407-1420Research output: Contribution to journal › Article › peer-review
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Multimodel Pathway Enrichment Methods for Functional Evaluation of Expression Regulation.
Kirik, U., Cifani, P., Albrekt, A.-S., Lindstedt, M., Heyden, A. & Levander, F., 2012, In: Journal of Proteome Research. 11, 5, p. 2955-2967Research output: Contribution to journal › Article › peer-review
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Allergen-specific immunotherapy and human antibody responses – an outcome and epitope-centric view
Ohlin, M. (PI), Lindstedt, M. (Researcher), Greiff, L. (Researcher) & Levander, F. (Researcher)
2026/01/01 → 2030/12/31
Project: Research
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Protein biomarker developments for breast cancer patient stratification
Levander, F. (PI), Ryden, L. (Researcher) & Vallon-Christersson, J. (Researcher)
Mrs. Berta Kamprad's Cancer Foundation
2026/01/01 → 2027/12/31
Project: Research
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NILS study (Non-invasive diagnostic of lymph node status)
Ryden, L. (PI), Dihge, L. (Researcher), Bendahl, P.-O. (Researcher), Zackrisson, S. (Researcher), Ohlsson, M. (Researcher), Dustler, M. (Researcher) & Levander, F. (Researcher)
Familjen Erling-Perssons Stiftelse, Bröstcancerförbundet, Sjöbergstiftelsen
2019/01/01 → 2027/12/31
Project: Research
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Antibody repertoires: Exploration of their role in allergic disease and facilitation of reliable analyses thereof
Thörnqvist, L. (Research student), Ohlin, M. (Supervisor), Levander, F. (Assistant supervisor), Lindstedt, M. (Assistant supervisor) & Greiff, L. (Assistant supervisor)
2017/08/21 → …
Project: Dissertation
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Enabling proteoform biomarker discovery
Levander, F. (PI)
Wallenberg AI, Autonomous Systems and Software Program (WASP)
2023/10/01 → 2025/12/31
Project: Research
Infrastructure
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National Bioinformatics Infrastructure Sweden
Ahrén, D. (Manager), Ringnér, M. (Manager), Levander, F. (Manager), Manoharan, L. (Manager), Oskolkov, N. (Manager), Vasquez, L. J. A. (Manager), Pyl, P. T. (Manager), Agarwal, P. (Manager), Li, Y. (Manager), Volpe, M. (Manager) & Kozjek, K. (Manager)
Department of BiologyInfrastructure