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Dive into the research topics where Gyula Hoffka is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations the last five years
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Mechanistic Elucidation and Stereochemical Consequences of Alternative Binding of Alkenyl Substrates by Engineered Arylmalonate Decarboxylase
van der Pol, E., Schlatzer, T., Hoffka, G., Di Geronimo, B., Eder, J., Schweiger, A. K., Karava, M., Gross, D., Fischer, R. C., Kracher, D., Kazlauskas, R., Miyamoto, K., Kamerlin, S. C. L., Breinbauer, R. & Kourist, R., 2025 Oct 29, In: Journal of the American Chemical Society. 147, 43, p. 39271-39283 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Complete computational design of high-efficiency Kemp elimination enzymes
Listov, D., Vos, E., Hoffka, G., Hoch, S. Y., Berg, A., Hamer-Rogotner, S., Dym, O., Kamerlin, S. C. L. & Fleishman, S. J., 2025 Jul 31, In: Nature. 643, 8074, p. 1421-1427 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Phosphorylation of ITIM motifs drives the structural transition of indoleamine 2,3-dioxygenase 1 between enzymatic and non-enzymatic states
Hoffka, G., Hornyák, L., Székvölgyi, L. & Miskei, M., 2025 Jun, In: Protein Science. 34, 6, e70152.Research output: Contribution to journal › Article › peer-review
Open Access -
Enzyme Enhancement Through Computational Stability Design Targeting NMR-Determined Catalytic Hotspots
Gutierrez-Rus, L. I., Vos, E., Pantoja-Uceda, D., Hoffka, G., Gutierrez-Cardenas, J., Ortega-Muñoz, M., Risso, V. A., Jimenez, M. A., Kamerlin, S. C. L. & Sanchez-Ruiz, J. M., 2025 May, In: Journal of the American Chemical Society. 147, 18, p. 14978-14996 19 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Receptor Binding for the Entry Mechanisms of SARS-CoV-2: Insights from the Original Strain and Emerging Variants
Mahdi, M., Kiarie, I. W., Mótyán, J. A., Hoffka, G., Al-Muffti, A. S., Tóth, A. & Tőzsér, J., 2025 May, In: Viruses. 17, 5, 691.Research output: Contribution to journal › Review article › peer-review
Open Access