Research output per year
Research output per year
Research output
- 1 - 50 out of 92 results
Search results
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2024
Retraction note: CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling (Nature Cell Biology, (2021), 23, 7, (758-770), 10.1038/s41556-021-00702-0)
Wang, S., Englund, E., Kjellman, P., Li, Z., Ahnlide, J. K., Rodriguez-Cupello, C., Saggioro, M., Kanzaki, R., Pietras, K., Lindgren, D., Axelson, H., Prinz, C. N., Swaminathan, V. & Madsen, C. D., 2024 Oct, In: Nature Cell Biology. 26, 10, p. 1817 1 p.Research output: Contribution to journal › Debate/Note/Editorial
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Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma
Sainero-Alcolado, L., Garde-Lapido, E., Snaebjörnsson, M. T., Schoch, S., Stevens, I., Ruiz-Pérez, M. V., Dyrager, C., Pelechano, V., Axelson, H., Schulze, A. & Arsenian-Henriksson, M., 2024 Feb 13, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 7, p. e2310479121Research output: Contribution to journal › Article › peer-review
Open Access -
2023
A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology
Petersen, J., Englmaier, L., Artemov, A. V., Poverennaya, I., Mahmoud, R., Bouderlique, T., Tesarova, M., Deviatiiarov, R., Szilvásy-Szabó, A., Akkuratov, E. E., Pajuelo Reguera, D., Zeberg, H., Kaucka, M., Kastriti, M. E., Krivanek, J., Radaszkiewicz, T., Gömöryová, K., Knauth, S., Potesil, D. & Zdrahal, Z. & 25 others, , 2023, In: Nature Communications. 14, 1, 3092.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification and validation of NFIA as a novel prognostic marker in renal cell carcinoma
de Alwis, R., Schoch, S., Islam, M., Möller, C., Ljungberg, B. & Axelson, H., 2023, In: The Journal of Pathology: Clinical Research. 9, 4, p. 261-272Research output: Contribution to journal › Article › peer-review
Open Access -
The Immunopeptidome from a Genomic Perspective: Establishing the Noncanonical Landscape of MHC Class I–Associated Peptides
Bedran, G., Gasser, H. C., Weke, K., Wang, T., Bedran, D., Laird, A., Battail, C., Zanzotto, F. M., Pesquita, C., Axelson, H., Rajan, A., Harrison, D. J., Palkowski, A., Pawlik, M., Parys, M., O’Neill, J. R., Brennan, P. M., Symeonides, S. N., Goodlett, D. R. & Litchfield, K. & 4 others, , 2023, In: Cancer immunology research. 11, 6, p. 742-762 21 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The Lund taxonomy for bladder cancer classification – from gene expression clustering to cancer cell molecular phenotypes, and back again
Höglund, M., Bernardo, C., Sjödahl, G., Eriksson, P., Axelson, H. & Liedberg, F., 2023, In: Journal of Pathology. 259, 4, p. 369-375Research output: Contribution to journal › Review article › peer-review
Open Access -
2022
Size-based isolation and detection of renal carcinoma cells from whole blood
De Alwis, R., Hansson, J., Lindgren, D., Schoch, S., Tejera, A., Scholtz, B., Elfving, P., Möller, C., Nilsson, H., Johansson, M. & Axelson, H., 2022 Mar 21, In: Molecular and clinical oncology. 16, 5, 11 p., 101.Research output: Contribution to journal › Article › peer-review
Open Access -
Dialysis as a Novel Adjuvant Treatment for Malignant Cancers
Hobro, S., Nilsson, A., Sternby, J., Öberg, C., Pietras, K., Axelson, H., Carneiro, A., Kinhult, S., Christensson, A., Fors, J., Maciejewski, S., Knox, J., Forsal, I., Källquist, L. & Roos, V., 2022, In: Cancers. 14, 20, 5054.Research output: Contribution to journal › Review article › peer-review
Open Access -
2021
The Irradiated brain microenvironment supports glioma stemness and survival via astrocyte-derived transglutaminase 2
Berg, T. J., Marques, C., Pantazopoulou, V., Johansson, E., Von Stedingk, K., Lindgren, D., Jeannot, P., Pietras, E. J., Bergström, T., Swartling, F. J., Governa, V., Bengzon, J., Belting, M., Axelson, H., Squatrito, M. & Pietras, A., 2021 Apr 1, In: Cancer Research. 81, 8, p. 2101-2115 15 p.Research output: Contribution to journal › Article › peer-review
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Soft Drink and Juice Consumption and Renal Cell Carcinoma Incidence and Mortality in the European Prospective Investigation into Cancer and Nutrition
Heath, A. K., Clasen, J. L., Jayanth, N. P., Jenab, M., Tjønneland, A., Petersen, K. E. N., Overvad, K., Srour, B., Katzke, V., Bergmann, M. M., Schulze, M. B., Masala, G., Krogh, V., Tumino, R., Catalano, A., Pasanisi, F., Brustad, M., Olsen, K. S., Skeie, G. & Luján-Barroso, L. & 12 others, , 2021, In: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 30, 6, p. 1270-1274Research output: Contribution to journal › Article › peer-review
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2020
Features of increased malignancy in eosinophilic clear cell renal cell carcinoma
Nilsson, H., Lindgren, D., Axelson, H., Brueffer, C., Saal, L., Lundgren, J. & Johansson, M., 2020 Dec, In: Journal of Pathology. 252, 4, p. 384-397 14 p.Research output: Contribution to journal › Article › peer-review
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Recurring urothelial carcinomas show genomic rearrangements incompatible with a direct relationship
Marzouka, N. A. D., Lindgren, D., Eriksson, P., Sjödahl, G., Bernardo, C., Liedberg, F., Axelson, H. & Höglund, M., 2020 Dec, In: Scientific Reports. 10, 1, 19539.Research output: Contribution to journal › Article › peer-review
Open Access -
The STRIPAK Complex Regulates Response to Chemotherapy Through p21 and p27
Rodriguez-Cupello, C., Dam, M., Serini, L., Wang, S., Lindgren, D., Englund, E., Kjellman, P., Axelson, H., García Mariscal, A. & Madsen, C., 2020 Mar 17, In: Frontiers in Cell and Developmental Biology. 8, 146.Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Tracing Renal Cell Carcinomas back to the Nephron
Lindgren, D., Sjölund, J. & Axelson, H., 2018 Jul, In: Trends in Cancer . 4, 7, p. 472-484Research output: Contribution to journal › Article › peer-review
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Patient-derived xenograft models reveal intratumor heterogeneity and temporal stability in neuroblastoma
Braekeveldt, N., Von Stedingk, K., Fransson, S., Martinez-Monleon, A., Lindgren, D., Axelson, H., Levander, F., Willforss, J., Hansson, K., Øra, I., Backman, T., Börjesson, A., Beckman, S., Esfandyari, J., Berbegall, A. P., Noguera, R., Karlsson, J., Koster, J., Martinsson, T. & Gisselsson, D. & 2 others, , 2018, In: Cancer Research. 78, 20, p. 5958-5969 12 p.Research output: Contribution to journal › Article › peer-review
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2017
Cell-Type-Specific Gene Programs of the Normal Human Nephron Define Kidney Cancer Subtypes
Lindgren, D., Eriksson, P., Krawczyk, K., Nilsson, H., Hansson, J., Veerla, S., Sjölund, J., Höglund, M., Johansson, M. E. & Axelson, H., 2017 Aug 8, In: Cell Reports. 20, 6, p. 1476-1489 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
CD44 interacts with HIF-2α to modulate the hypoxic phenotype of perinecrotic and perivascular glioma cells
Johansson, E., Grassi, E., Pantazopoulou, V., Tong, B., Lindgren, D., Berg, T., Pietras, E., Axelson, H. & Pietras, A., 2017 Aug, In: Cell Reports. 20, 7, p. 1641-1653Research output: Contribution to journal › Article › peer-review
Open Access -
Overexpression of functional SLC6A3 in clear cell renal cell carcinoma
Hansson, J., Lindgren, D., Nilsson, H., Johansson, E., Johansson, M., Gustavsson, L. & Axelson, H., 2017, In: Clinical Cancer Research. 23, 8, p. 2105-2115Research output: Contribution to journal › Article › peer-review
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2016
Simultaneous targeted activation of Notch1 and Vhl-disruption in the kidney proximal epithelial tubular cells in mice
Johansson, E., Rönö, B., Johansson, M., Lindgren, D., Möller, C., Axelson, H. & Smith, E. M. K., 2016 Aug 6, In: Scientific Reports. 6, 10 p., 30739.Research output: Contribution to journal › Article › peer-review
Open Access -
Species diversity regarding the presence of proximal tubular progenitor cells of the kidney
Hansson, J., Ericsson, A. E., Axelson, H. & Johansson, M., 2016, In: European Journal of Histochemistry. 60, 1, p. 2567Research output: Contribution to journal › Article › peer-review
Open Access -
2015
Individual patient risk stratification of high-risk neuroblastomas using a two-gene score suited for clinical use.
von Stedingk, K., De Preter, K., Vandesompele, J., Noguera, R., Øra, I., Koster, J., Versteeg, R., Påhlman, S., Lindgren, D. & Axelson, H., 2015, In: International Journal of Cancer. 137, 4, p. 868-877Research output: Contribution to journal › Article › peer-review
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Primary clear cell renal carcinoma cells display minimal mitochondrial respiratory capacity resulting in pronounced sensitivity to glycolytic inhibition by 3-Bromopyruvate.
Nilsson, H., Lindgren, D., Mandahl Forsberg, A., Mulder, H., Axelson, H. & Johansson, M., 2015, In: Cell Death & Disease. 6, e1585.Research output: Contribution to journal › Article › peer-review
Open AccessFile448 Downloads (Pure) -
The Axl-Regulating Tumor Suppressor miR-34a Is Increased in ccRCC but Does Not Correlate with Axl mRNA or Axl Protein Levels.
Fritz, H., Gustafsson, A., Ljungberg, B., Ceder, Y., Axelson, H. & Dahlbäck, B., 2015, In: PLoS ONE. 10, 8, e0135991.Research output: Contribution to journal › Article › peer-review
Open AccessFile164 Downloads (Pure) -
2014
Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response.
Lehn, S., Tobin, N. P., Sims, A. H., Stål, O., Jirström, K., Axelson, H. & Landberg, G., 2014, In: BMC Cancer. 14, 1, 119.Research output: Contribution to journal › Article › peer-review
Open AccessFile284 Downloads (Pure) -
Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.
Rankin, E. B., Fuh, K. C., Castellini, L., Viswanathan, K., Finger, E. C., Diep, A. N., LaGory, E. L., Kariolis, M. S., Chan, A., Lindgren, D., Axelson, H., Miao, Y. R., Krieg, A. J. & Giaccia, A. J., 2014, In: Proceedings of the National Academy of Sciences. 111, 37, p. 13373-13378Research output: Contribution to journal › Article › peer-review
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Epithelial and Stromal MicroRNA Signatures of Columnar Cell Hyperplasia Linking Let-7c to Precancerous and Cancerous Breast Cancer Cell Proliferation.
Björner, S., Fitzpatrick, P. A., Li, Y., Allred, C., Howell, A., Ringberg, A., Olsson, H., Miller, C. J., Axelson, H. & Landberg, G., 2014, In: PLoS ONE. 9, 8, e105099.Research output: Contribution to journal › Article › peer-review
Open AccessFile701 Downloads (Pure) -
Evidence for a morphologically distinct and functionally robust cell type in the proximal tubules of human kidney.
Hansson, J., Hultenby, K., Cramnert, C., Pontén, F., Jansson, H., Lindgren, D., Axelson, H. & Johansson, M., 2014, In: Human Pathology. 45, 2, p. 382-393Research output: Contribution to journal › Article › peer-review
File612 Downloads (Pure) -
The HER2-Encoded miR-4728-3p Regulates ESR1 through a Non-Canonical Internal Seed Interaction.
Newie, I., Sökilde, R., Persson, H., Grabau, D., Rego, N., Kvist, A., von Stedingk, K., Axelson, H., Borg, Å., Vallon-Christersson, J. & Rovira, C., 2014, In: PLoS ONE. 9, 5, e97200.Research output: Contribution to journal › Article › peer-review
Open AccessFile284 Downloads (Pure) -
The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma.
Fritz, H., Lindgren, D., Ljungberg, B., Axelson, H. & Dahlbäck, B., 2014, In: European Journal of Cancer. 50, 10, p. 1758-1765Research output: Contribution to journal › Article › peer-review
File238 Downloads (Pure) -
2013
Effects of TGF-β signaling in Clear Cell Renal Cell Carcinoma cells.
Boström, A.-K., Lindgren, D., Johansson, M. & Axelson, H., 2013, In: Biochemical and Biophysical Research Communications. 435, 1, p. 126-133Research output: Contribution to journal › Article › peer-review
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Kidney cancer.
Johansson, M. & Axelson, H., 2013, In: Seminars in Cancer Biology. 23, 1, p. 1-2Research output: Contribution to journal › Debate/Note/Editorial › peer-review
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Renal stem cells and their implications for kidney cancer.
Axelson, H. & Johansson, M. E., 2013, In: Seminars in Cancer Biology. 23, 1, p. 56-61Research output: Contribution to journal › Review article › peer-review
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snoRNPs Regulate Telomerase Activity in Neuroblastoma and Are Associated with Poor Prognosis.
von Stedingk, K., Koster, J., Piqueras, M., Noguera, R., Navarro, S., Påhlman, S., Versteeg, R., Øra, I., Gisselsson Nord, D., Lindgren, D. & Axelson, H., 2013, In: Translational Oncology. 6, 4, p. 447-457 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2012
Sarcomatoid conversion of clear cell renal cell carcinoma in relation to epithelial-to-mesenchymal transition.
Boström, A.-K., Möller, C., Nilsson, E., Elfving, P., Axelson, H. & Johansson, M., 2012, In: Human Pathology. 43, p. 708-719Research output: Contribution to journal › Article › peer-review
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2011
Isolation and characterization of progenitor-like cells from human renal proximal tubules.
Lindgren, D., Boström, A.-K., Nilsson, K., Hansson, J., Sjölund, J., Möller, C., Jirström, K., Nilsson, E., Landberg, G., Axelson, H. & Johansson, M., 2011, In: American Journal of Pathology. 178, 2, p. 828-837Research output: Contribution to journal › Article › peer-review
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JAG2 induction in hypoxic tumor cells alters Notch signaling and enhances endothelial cell tube formation.
Pietras, A., von Stedingk, K., Lindgren, D., Påhlman, S. & Axelson, H., 2011, In: Molecular Cancer Research. 9, p. 626-636Research output: Contribution to journal › Article › peer-review
File268 Downloads (Pure) -
The Notch and TGF-beta Signaling Pathways Contribute to the Aggressiveness of Clear Cell Renal Cell Carcinoma.
Sjölund, J., Boström, A.-K., Lindgren, D., Manna, S., Moustakas, A., Ljungberg, B., Johansson, M., Fredlund, E. & Axelson, H., 2011, In: PLoS ONE. 6, 8, e23057.Research output: Contribution to journal › Article › peer-review
Open AccessFile213 Downloads (Pure) -
2010
The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma
Mestdagh, P., Boström, A.-K., Impens, F., Fredlund, E., Van Peer, G., De Antonellis, P., von Stedingk, K., Ghesquiere, B., Schulte, S., Dews, M., Thomas-Tikhonenko, A., Schulte, J. H., Zollo, M., Schramm, A., Gevaert, K., Axelson, H., Speleman, F. & Vandesompele, J., 2010, In: Molecular Cell. 40, 5, p. 762-773Research output: Contribution to journal › Article › peer-review
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2009
CRIM1 is localized to the podocyte filtration slit diaphragm of the adult human kidney
Nyström, J., Hultenby, K., Ek, S., Sjölund, J., Axelson, H., Jirström, K., Saleem, M., Nilsson, K. & Johansson, M., 2009, In: Nephrology Dialysis Transplantation. 24, 7, p. 2038-2044Research output: Contribution to journal › Article › peer-review
Open Access -
Editorial Comment on: Inflammatory Protein Serum Amyloid A1 Marks a Subset of Conventional Renal Cell Carcinomas with Fatal Outcome.
Axelson, H. & Johansson, M., 2009, In: European Urology.Research output: Contribution to journal › Article › peer-review
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Gas6 and the receptor tyrosine kinase Axl in clear cell renal cell carcinoma.
Gustafsson, A., Boström, A.-K., Ljungberg, B., Axelson, H. & Dahlbäck, B., 2009, In: PLoS ONE. 4, 10, e7575.Research output: Contribution to journal › Article › peer-review
Open AccessFile233 Downloads (Pure) -
HIF-1alpha induces MXI1 by alternate promoter usage in human neuroblastoma cells.
Löfstedt, T., Fredlund, E., Noguera, R., Navarro, S., Holmquist Mengelbier, L., Beckman, S., Påhlman, S. & Axelson, H., 2009, In: Experimental Cell Research. 315, 11, p. 1924-1936Research output: Contribution to journal › Article › peer-review
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2008
Impaired Function of Hematopoietic Stem Cells with Abrogated Hypoxia Induced Expression of Vascular Endothelial Growth Factor
Rehn, M., Reckzeh, K., Olsson, A., Axelson, H. & Cammenga, J., 2008, In: Blood. 112, 11, p. 110-110Research output: Contribution to journal › Published meeting abstract › peer-review
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Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo
Sjölund, J., Johansson, M., Manna, S., Norin, C., Pietras, A., Beckman, S., Nilsson, E., Ljungberg, B. & Axelson, H., 2008, In: Journal of Clinical Investigation. 118, 1, p. 217-228Research output: Contribution to journal › Article › peer-review
Open Access -
2007
The Lim-only protein LMO2 acts as a positive regulator of erythroid differentiation
Hansson, A., Zetterblad, J., van Duren, C., Axelson, H. & Jönsson, J.-I., 2007, In: Biochemical and Biophysical Research Communications. 364, 3, p. 675-681Research output: Contribution to journal › Article › peer-review
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2006
Eyeing tumorigenesis: Notch signaling and epigenetic silencing of Rb in Drosophila.
Axelson, H., 2006, In: BioEssays. 28, 7, p. 692-695Research output: Contribution to journal › Article › peer-review
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2005
Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells.
Stockhausen, M., Sjölund, J., Manetopoulos, C. & Axelson, H., 2005, In: British Journal of Cancer. 92, 4, p. 751-759Research output: Contribution to journal › Article › peer-review
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High ID2 protein expression correlates with a favourable prognosis in patients with primary breast cancer and reduces cellular invasiveness of breast cancer cells.
Stighall, M., Manetopoulos, C., Axelson, H. & Landberg, G., 2005, In: International Journal of Cancer. 115, 3, p. 403-411Research output: Contribution to journal › Article › peer-review
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Hypoxia-induced dedifferentiation of tumor cells - A mechanism behind heterogeneity and aggressiveness of solid tumors.
Axelson, H., Fredlund, E., Ovenberger, M., Landberg, G. & Påhlman, S., 2005, In: Seminars in Cell & Developmental Biology. 16, 4-5, p. 554-563Research output: Contribution to journal › Review article › peer-review
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Inhibition of EBF function by active Notch signaling reveals a novel regulatory pathway in early B-cell development
Smith, E., Akerblad, P., Kadesch, T., Axelson, H. & Sigvardsson, M., 2005, In: Blood. 106, 6, p. 1995-2001Research output: Contribution to journal › Article › peer-review
Open Access