Helena Elding Larsson

Helena Elding Larsson


If you made any changes in Pure these will be visible here soon.

Personal profile


Pediatric autoimmune disorders, such as type 1 diabetes and autoimmune thyroid disease may affect as many as 2-3 % of all children. Genetic factors are associated with these diseases, but environmental factors may trigger the autoimmune process in the genetically susceptible individuals. The nature and role of environmental factors in the disease processes are still to be defined. 

The aims of our research are to identify genetic and immunological risk factors for type 1 diabetes and autoimmune thyroiditis, as well as predictive factors for the diseases, and ultimately delay or prevent the disease onset through primary or secondary prevention.

The research is based upon our large prospective population-based studies Diabetes Prediction in Skåne (DiPiS) and The Environmental Determinants of Diabetes in the young (TEDDY), and large scale screening at birth for high type 1 diabetes risk in teh ASTRID study within the Global Platform for Autoimmune Diabetes (GPPAD). In an number of clinical trials we are aiming to prevent or delay the disease. In the primary prevention studies POInT and SINTIA, children with high genetic risk are given oral inuslin/placebo and probiotics/placebo. In our Diabetes Prevention – Immune Tolerance (DiAPREV-IT), chilren with ongoing autoimmunity has been given GAD-Alum as secondary prevention. Immunological studies are ongoing.

In our prospective cohorts of children with risk for type 1 diabetes, we are additionally testing for thyroid disease, to be able to investigate overlap and the impact of genetic and environmental exposures to the development of autoimmune thyroiditis.



Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

UKÄ subject classification

  • Endocrinology and Diabetes
  • Pediatrics

Free keywords

  • type 1 diabetes
  • autoimmune thyroiditis
  • narcolepsy


Dive into the research topics where Helena Elding Larsson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or