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Personal profile

Research

We are interested in how aging and neurodegenerative diseases affect the brain, neural cells and neural stem cells. Using novel stem cell, reprogramming and genome editing technologies we are studying how genetic pathways involved in aging and neurodegenerative disease affect formation and function of neural cells. We also have a strong interest in basic stem cell biology with a clear focus on neural stem cells and neurogenesis in the adult and aging brain.

Therefore, our aims are to develop cellular models of human neuronal aging and degeneration, to investigate underlying mechanisms responsible for dysfunction in neurons and neural stem cells in the aging and diseased brain and to dissect the regulation of normal neurogenesis.

UKÄ subject classification

  • Medical and Health Sciences

Keywords

  • Stem Cells
  • Aging
  • Neurodegneration
  • Reprogramming
  • Neural Stem Cells
  • Neurogenesis
  • Dementia

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