Ingvar Syk

2024

Risk of recurrence in high-risk T1 colon cancer following endoscopic and surgical resection: registry-based cohort study

Nilsson, E., Wetterholm, E., Syk, I., Thorlacius, H. & Rönnow, C. F., 2024 Jun 1, In: BJS Open. 8, 3, zrae053.

Research output: Contribution to journal › Article › peer-review

Open Access

Efficacy of hyperthermic intraperitoneal chemotherapy in colorectal cancer: A phase I and III open label randomized controlled registry-based clinical trial protocol

Ghanipour, L., Palmer, G. J., Nilsson, P. J., Nordenvall, C., Frödin, J. E., Lindskog, E. B., Asplund, D., Swartling, T., Graf, W., Birgisson, H., Syk, I., Verwaal, V., Brändstedt, J. & Cashin, P. H., 2024 Mar, In: PLoS ONE. 19, 3 March, e0294018.

Research output: Contribution to journal › Article › peer-review

Open Access

A Validation of the Swedish Colorectal Cancer Register – With Focus on Histopathology, Complications and Recurrences

Arnarson, Ö., Moberger, P., Sköldberg, F., Smedh, K., Birgisson, H. & Syk, I., 2024, In: Clinical Epidemiology. 16, p. 525-532 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Who should operate patients presenting with emergent colon cancer? A comparison of short- and long-term outcome depending on surgical sub-specialization

Arnarson, Ö., Syk, I. & Butt, S. T., 2023 Dec, In: World Journal of Emergency Surgery. 18, 1, 3.

Research output: Contribution to journal › Article › peer-review

Open Access

Risk Factors for Postoperative Complications Following Resection of Colorectal Liver Metastases and the Impact on Long-Term Survival: A Population-Based National Cohort Study

Scherman, P., Syk, I., Holmberg, E., Naredi, P. & Rizell, M., 2023 Sept, In: World Journal of Surgery. 47, 9, p. 2230-2240 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Abdominal Closure With Reinforcing Suture Decreases Incisional Hernia Incidence After CRS/HIPEC

Wenzelberg, C., Petersson, U., Syk, I., Ekberg, O. & Rogmark, P., 2023, In: Journal of abdominal wall surgery : JAWS. 2, 11188.

Research output: Contribution to journal › Article › peer-review

Open Access

High resection rates of colorectal liver metastases after standardized follow-up and multimodal management: an outcome study within the COLOFOL trial

Scherman, P., Hansdotter, P., Holmberg, E., Viborg Mortensen, F., Petersen, S. H., Rizell, M., Naredi, P., Syk, I. & COLOFOL Study Group, 2023, In: HPB. 25, 7, p. 766-774

Research output: Contribution to journal › Article › peer-review

Open Access

Short- and long-term outcomes following bridge to surgery and emergency resection in acute malignant large bowel obstruction

Arnarson, Ö., Axmarker, T. & Syk, I., 2023, In: Colorectal Disease. 25, 4, p. 669-678

Research output: Contribution to journal › Article › peer-review

Transanal formation of anastomosis using C-REX device is feasible and effective in high anterior resection

Vilhjalmsson, D., Lepsenyi, M., Syk, I., Grönberg, A. & Thorlacius, H., 2023, In: International Journal of Colorectal Disease. 38, 1, 127.

Research output: Contribution to journal › Article › peer-review

Open Access

Treatment and survival of patients with metachronous colorectal lung metastases

Hansdotter, P., Scherman, P., Nikberg, M., Petersen, S. H., Holmberg, E., Rizell, M., Naredi, P., Syk, I. & COLOFOL Study Group, 2023, In: Journal of Surgical Oncology. 127, 5, p. 806-814

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Delineating the intra-patient heterogeneity of molecular alterations in treatment-naïve colorectal cancer with peritoneal carcinomatosis

Siesing, C., Petersson, A., Ulfarsdottir, T., Chattopadhyay, S., Nodin, B., Eberhard, J., Brändstedt, J., Syk, I., Gisselsson Nord, D. & Jirström, K., 2022 Jul, In: Modern Pathology. 35, 7, p. 979-988 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Lymphovascular Infiltration, Not Depth of Invasion, is the Critical Risk Factor of Metastases in Early Colorectal Cancer: Retrospective Population-based Cohort Study on Prospectively Collected Data, including Validation

Ronnow, C. F., Arthursson, V., Toth, E., Krarup, P. M., Syk, I. & Thorlacius, H., 2022 Jan 1, In: Annals of Surgery. 275, 1, p. E148-E154

Research output: Contribution to journal › Article › peer-review

Risk of recurrence after endoscopic resection of nonpedunculated T1 colorectal cancer

Arthursson, V., Medic, S., Syk, I., Rönnow, C.-F. & Thorlacius, H., 2022, In: Endoscopy. 54, 11, p. 1071-1077

Research output: Contribution to journal › Article › peer-review

2021

Patterns and resectability of colorectal cancer recurrences: outcome study within the COLOFOL trial

Hansdotter, P., Scherman, P., Petersen, S. H., Mikalonis, M., Holmberg, E., Rizell, M., Naredi, P., Syk, I. & COLOFOL Study Group, 2021 Jul 6, In: BJS Open. 5, 4

Research output: Contribution to journal › Article › peer-review

Open Access

Long-term survival after self-expanding metallic stent or stoma decompression as bridge to surgery in acute malignant large bowel obstruction

Axmarker, T., Leffler, M., Lepsenyi, M., Thorlacius, H. & Syk, I., 2021 Mar 5, In: BJS Open. 5, 2

Research output: Contribution to journal › Article › peer-review

Open Access

CXCL2-CXCR2 axis mediates αV integrin-dependent peritoneal metastasis of colon cancer cells

Lepsenyi, M., Algethami, N., Al-Haidari, A. A., Algaber, A., Syk, I., Rahman, M. & Thorlacius, H., 2021, In: Clinical and Experimental Metastasis. 38, 4, p. 401-410 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Impact of patient, primary tumor and metastatic pattern including tumor location on survival in patients undergoing ablation or resection for colorectal liver metastases: A population-based national cohort study

Scherman, P., Syk, I., Holmberg, E., Naredi, P. & Rizell, M., 2021, In: European Journal of Surgical Oncology. 47, 2, p. 375-383

Research output: Contribution to journal › Article › peer-review

Open Access

No benefit of more intense follow-up after surgery for colorectal cancer in the risk group with elevated CEA levels – An analysis within the COLOFOL randomized clinical trial

Egenvall, M., Martling, A., Veres, K., Horváth-Puhó, E., Wille-Jørgensen, P., Høirup Petersen, S., Laurberg, S., Sørensen, H. T., Syk, I., Buchwald, P. (Contributor) & COLOFOL Study Group, 2021, In: European Journal of Surgical Oncology. 47, 8, p. 2053-2059

Research output: Contribution to journal › Article › peer-review

2020

MicroRNA-340-5p inhibits colon cancer cell migration via targeting of RhoA

Algaber, A., Al-Haidari, A., Madhi, R., Rahman, M., Syk, I. & Thorlacius, H., 2020 Oct 9, In: Scientific Reports. 10, 1, p. 16934

Research output: Contribution to journal › Article › peer-review

Open Access

Outcomes of Simultaneous Resections and Classical Strategy for Synchronous Colorectal Liver Metastases in Sweden: A Nationwide Study with Special Reference to Major Liver Resections

Valdimarsson, V. T., Syk, I., Lindell, G., Sandström, P., Isaksson, B., Rizell, M., Norén, A., Ardnor, B. & Sturesson, C., 2020 Mar 17, In: World Journal of Surgery.

Research output: Contribution to journal › Article › peer-review

Open Access

Influence of primary tumour and patient factors on survival in patients undergoing curative resection and treatment for liver metastases from colorectal cancer

Scherman, P., Syk, I., Holmberg, E., Naredi, P. & Rizell, M., 2020 Feb, In: BJS Open. 4, 1, p. 118-132 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Interventions to reduce dehydration related to defunctioning loop ileostomy after low anterior resection in rectal cancer: a prospective cohort study

Munshi, E., Bengtsson, E., Blomberg, K., Syk, I. & Buchwald, P., 2020, In: ANZ Journal of Surgery. 90, 9, p. 1627-1631

Research output: Contribution to journal › Article › peer-review

Travel time to care does not affect survival for patients with colorectal cancer in northern Sweden: A data linkage study from the Risk North database

Sjöström, O., Dahlin, A. M., Silander, G., Syk, I., Melin, B. & Hellquist, B. N., 2020, In: PLoS ONE. 15, 8, e0236799.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

High Tie or not in Resection for Cancer in the Sigmoid Colon?

Olofsson, F., Buchwald, P., Elmståhl, S. & Syk, I., 2019 Sept 1, In: Scandinavian Journal of Surgery. 108, 3, p. 227-232 6 p.

Research output: Contribution to journal › Article › peer-review

Peritoneal mesothelioma in Sweden: A population-based study

Cashin, P. H., Jansson Palmer, G., Asplund, D., Graf, W. & Syk, I., 2019, In: Cancer Medicine. 8, 14, p. 6468-6475

Research output: Contribution to journal › Article › peer-review

Open Access

Postoperative complications following colonic resection for cancer are associated with impaired long-term survival

Arnarson, Butt-Tuna, S. & Syk, I., 2019, In: Colorectal Disease. 21, 7, p. 805-815

Research output: Contribution to journal › Article › peer-review

2018

Disparities in colorectal cancer between Northern and SouthernSweden–a report from the new RISK North database

Sjöström, O., Silander, G., Syk, I., Henriksson, R., Melin, B. & Hellquist, B. N., 2018 Dec 2, In: Acta Oncologica. 57, 12, p. 1622-1630

Research output: Contribution to journal › Article › peer-review

Open Access

Effect of more vs less frequent follow-up testing on overall and colorectal cancer–Specific mortality in patients with stage II or III colorectal cancer the COLOFOL randomized clinical trial

Wille-Jørgensen, P., Syk, I., Smedh, K., Laurberg, S., Nielsen, D. T., Petersen, S. H., Renehan, A. G., Horváth-Puho, E., Påhlman, L., Sørensen, H. T. & COLOFOL Study Group, 2018 May 22, In: JAMA - Journal of the American Medical Association. 319, 20, p. 2095-2103 9 p.

Research output: Contribution to journal › Article › peer-review

MiR-155-5p controls colon cancer cell migration via post-transcriptional regulation of Human Antigen R (HuR)

Al-Haidari, A., Algaber, A., Madhi, R., Syk, I. & Thorlacius, H., 2018 May 1, In: Cancer Letters. 421, p. 145-151 7 p.

Research output: Contribution to journal › Article › peer-review

Outcomes of liver-first strategy and classical strategy for synchronous colorectal liver metastases in Sweden

Valdimarsson, V. T., Syk, I., Lindell, G., Norén, A., Isaksson, B., Sandström, P., Rizell, M., Ardnor, B. & Sturesson, C., 2018 May, In: HPB. 20, 5, p. 441-447

Research output: Contribution to journal › Article › peer-review

2017

One-year results of the SCANDIV randomized clinical trial of laparoscopic lavage versus primary resection for acute perforated diverticulitis

Schultz, J. K., Wallon, C., Blecic, L., Forsmo, H. M., Folkesson, J., Buchwald, P., Kørner, H., Dahl, F. A., Øresland, T., Yaqub, S. & the SCANDIV Study Group, 2017 Sept 1, In: British Journal of Surgery. 104, 10, p. 1382-1392 11 p.

Research output: Contribution to journal › Article › peer-review

Registries on peritoneal surface malignancies throughout the world, their use and their options

Verwaal, V. J., Rau, B., Jamali, F., Gilly, F. N., de Hingh, I., Takala, H., Syk, I., Pelz, J., Mulsow, J., van der Speeten, K., Shigeki, K., Iversen, L. H., Mohamed, F., Glehen, O., Younan, R., Yarema, R., Gonzalez-Moreno, S., O’Dwyer, S., Yonemura, Y. & Sugarbaker, P., 2017 Jul 4, In: International Journal of Hyperthermia. 33, 5, p. 528-533 6 p.

Research output: Contribution to journal › Article › peer-review

Liver-first strategy for synchronous colorectal liver metastases: an intention-to-treat analysis

Sturesson, C., Valdimarsson, V. T., Blomstrand, E., Eriksson, S., Nilsson, J., Syk, I. & Lindell, G., 2017 Jan 1, In: HPB. 19, 1, p. 52-58 7 p.

Research output: Contribution to journal › Article › peer-review

MiR-155-5p positively regulates CCL17-induced colon cancer cell migration by targeting RhoA

Al-Haidari, A. A., Syk, I. & Thorlacius, H., 2017, In: Oncotarget. 8, 9, p. 14887-14896 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Optimal fractionation of preoperative radiotherapy and timing to surgery for rectal cancer (Stockholm III): A multicentre, randomised, non-blinded, phase 3, non-inferiority trial

Erlandsson, J., Holm, T., Pettersson, D., Berglund, Å., Cedermark, B., Radu, C., Johansson, H., Machado, M., Hjern, F., Hallböök, O., Syk, I., Glimelius, B. & Martling, A., 2017, In: The Lancet Oncology. 18, 3, p. 336-346

Research output: Contribution to journal › Article › peer-review

2016

Cytoreductive surgery and intraperitoneal chemotherapy versus systemic chemotherapy for colorectal peritoneal metastases: A randomised trial.

Cashin, P. H., Mahteme, H., Spång, N., Syk, I., Frödin, J. E., Torkzad, M., Glimelius, B. & Graf, W., 2016, In: European Journal of Cancer. 53, p. 155-162

Research output: Contribution to journal › Article › peer-review

No benefit of extended mesenteric resection with central vascular ligation in right-sided colon cancer.

Olofsson, F., Buchwald, P., Elmståhl, S. & Syk, I., 2016, In: Colorectal Disease.

Research output: Contribution to journal › Article › peer-review

The COLOFOL trial: study design and comparison of the study population with the source cancer population.

Hansdotter Andersson, P., Wille-Jørgensen, P., Horváth-Puhó, E., Petersen, S. H., Martling, A., Sørensen, H. T. & Syk, I., 2016, In: Clinical Epidemiology. 8, p. 15-21

Research output: Contribution to journal › Article › peer-review

2015

Laparoscopic lavage vs primary resection for acute perforated diverticulitis: The SCANDIV randomized clinical trial

Schultz, J. K., Yaqub, S., Wallon, C., Blecic, L., Forsmo, H. M., Folkesson, J., Buchwald, P., Körner, H., Dahl, F. A., Øresland, T., Syk, I. (Contributor), Vilhjalmsson, D. (Contributor) & SCANDIV Study Group, 2015 Oct 6, In: JAMA - Journal of the American Medical Association. 314, 13, p. 1364-1375

Research output: Contribution to journal › Article › peer-review