Research output per year
Research output per year
Personal profile
Research
Dr. Jenny Nelander Wahlestedt has a MSc in Biomedicine from Lund University and did her PhD education at Lund University with Prof. Malin Parmar, where she studied the human ventral mesencephalon with focus on mesencephalic dopaminergic neurons. Dr. Wahlestedt defended her PhD thesis (Characterization of human dopaminergic neurons in the developing mesencephalon and upon differentiation of stem cells - for cell replacement therapy in Parkinson's disease) in 2013.
After her PhD studies she was employed at Skåne University Hospital in Lund, being responsible for tissue and cell preparation for the clinical trial TransEuro (https://transeuro.org.uk/pages/partners.html), in which patients with Parkinson´s disease was transplanted with dopaminergic neurons derived from human fetal tissue. In 2017 she was recruited back to the research group of Prof. Malin Parmar as a staff scientist, mainly focusing on the translational work required to introduce hESC derived dopaminergic neurons to the clinic, the STEM-PD trial.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Subject classification (UKÄ)
- Neurology
- Medical and Health Sciences
- Basic Medicine
- Neurosciences
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Collaborations the last five years
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TARGET-seq: Linking single-cell transcriptomics of human dopaminergic neurons with their target specificity
Fiorenzano, A., Storm, P., Sozzi, E., Bruzelius, A., Corsi, S., Kajtez, J., Mudannayake, J., Nelander, J., Mattsson, B., Åkerblom, M., Björklund, T., Björklund, A. & Parmar, M., 2024 Nov 19, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 47, p. 1-12 e2410331121.Research output: Contribution to journal › Article › peer-review
Open Access -
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD
Kirkeby, A., Nelander, J., Hoban, D. B., Rogelius, N., Bjartmarz, H., Storm, P., Fiorenzano, A., Adler, A. F., Vale, S., Mudannayake, J., Zhang, Y., Cardoso, T., Mattsson, B., Landau, A. M., Glud, A. N., Sørensen, J. C., Lillethorup, T. P., Lowdell, M., Carvalho, C. & Bain, O. & 10 others, , 2023 Oct 5, In: Cell Stem Cell. 30, 10, p. 1299-1314 26 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells
Rifes, P., Isaksson, M., Rusimbi, C., Santoja, A. R., Wahlestedt, J. N., Laurell, T. & Kirkeby, A., 2023, In: Stem Cell Research & Therapy. 14, 1, 16 p., 354.Research output: Contribution to journal › Article › peer-review
Open Access -
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain
Birtele, M., Storm, P., Sharma, Y., Kajtez, J., Wahlestedt, J. N., Sozzi, E., Nilsson, F., Stott, S., He, X. L., Mattsson, B., Ottosson, D. R., Barker, R. A., Fiorenzano, A. & Parmar, M., 2022 Dec, In: Development: For advances in developmental biology and stem cells. 149, 23, dev200504.Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluation of TH-Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons
Fiorenzano, A., Birtele, M., Wahlestedt, J. N. & Parmar, M., 2021 Jan, In: Heliyon. 7, 1, e06006.Research output: Contribution to journal › Article › peer-review
Open AccessFile91 Downloads (Pure)
Projects
- 1 Active
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STEM-PD study
Parmar, M. (PI), Kirkeby, A. (Researcher), Barker, R. (Researcher), Paul-Visse, G. (Researcher), Widner, H. (Researcher), Bjartmarz, H. (Researcher), Nelander, J. (Researcher), Van Vliet, T. (Researcher) & Piccini, P. (Researcher)
The Swedish Parkinson Foundation, Parkinsonfonden, Swedish Research Council
2022/11/01 → …
Project: Research
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SVT Rapport:2024-05-06
Parmar, M. (Interviewee) & Nelander, J. (Participant)
2024 May 6Activity: Other › Media participation
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GForce-PD: annual meeting 2018
Kirkeby, A. (Keynote/plenary speaker), Parmar, M. (Chair), Björklund, A. (Chair), Nelander Wahlestedt, J. (Contributor), Lindvall, O. (Contributor) & Grealish, S. (Contributor)
2018 Apr 19 → 2018 Apr 20Activity: Talk or presentation › Invited talk