Research output per year
Research output per year
Personal profile
Research
Our lab is interested in transposable elements and how these viral-like sequences influence human brain evolution, neurodegenerative diseases, brain tumors and ageing. Our expertise includes human stem cell cultures, viral vectors, gene editing, cellular reprogramming and bioinformatical analysis of transposons.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Subject classification (UKÄ)
- Neurosciences
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Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Peripherally administered TNF inhibitor is not protective against α-synuclein-induced dopaminergic neuronal death in rats
Christiansen, J. R., Ferreira, S. A., Szymkowski, D. E., Jakobsson, J., Tansey, M. G. & Romero-Ramos, M., 2025, In: Neurobiology of Disease. 206, 106803.Research output: Contribution to journal › Article › peer-review
Open Access -
Protumoral lipid droplet-loaded macrophages are enriched in human glioblastoma and can be therapeutically targeted
Governa, V., de Oliveira, K. G., Bång-Rudenstam, A., Offer, S., Cerezo-Magaña, M., Li, J., Beyer, S., Johansson, M. C., Månsson, A. S., Edvardsson, C., Durmo, F., Gustafsson, E., Boukredine, A., Jeannot, P., Schmidt, K., Gezelius, E., Menard, J. A., Garza, R., Jakobsson, J. & de Neergaard, T. & 11 others, , 2024 Oct 30, In: Science Translational Medicine. 16, 771, p. eadk1168Research output: Contribution to journal › Article › peer-review
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DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor
Pandiloski, N., Horváth, V., Karlsson, O., Koutounidou, S., Dorazehi, F., Christoforidou, G., Matas-Fuentes, J., Gerdes, P., Garza, R., Jönsson, M. E., Adami, A., Atacho, D. A. M., Johansson, J. G., Englund, E., Kokaia, Z., Jakobsson, J. & Douse, C. H., 2024 Aug 30, In: Nature Communications. 15, 7534.Research output: Contribution to journal › Article › peer-review
Open Access -
The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1
Gustavsson, E. K., Sethi, S., Gao, Y., Brenton, J. W., García-Ruiz, S., Zhang, D., Garza, R., Reynolds, R. H., Evans, J. R., Chen, Z., Grant-Peters, M., Macpherson, H., Montgomery, K., Dore, R., Wernick, A. I., Arber, C., Wray, S., Gandhi, S., Esselborn, J. & Blauwendraat, C. & 15 others, , 2024 Jun 28, In: Science Advances. 10, 26, eadk1296.Research output: Contribution to journal › Article › peer-review
Open Access -
Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease
Horváth, V., Garza, R., Jönsson, M. E., Johansson, P. A., Adami, A., Christoforidou, G., Karlsson, O., Castilla Vallmanya, L., Koutounidou, S., Gerdes, P., Pandiloski, N., Douse, C. H. & Jakobsson, J., 2024, In: Nature Structural & Molecular Biology. 31, 10, p. 1543-1556Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Downloads (Pure)
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Epigenetic mechanisms governing human brain aging
Jakobsson, J. (PI)
Hans-Gabriel och Alice Trolle-Wachtmeisters Stiftelse
2023/11/27 → 2026/04/30
Project: Research
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Transposable elements and the evolution of the human brain
Jakobsson, J. (PI)
2023/07/01 → 2025/12/31
Project: Research
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The role of human-specific, transposon-controlled lncRNAs in brain development
Jakobsson, J. (PI)
2023/01/01 → 2027/12/31
Project: Research
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Epigenetics and glioblastoma: a role for line-1 transposable elements
Jakobsson, J. (PI)
2023/01/01 → 2026/12/31
Project: Research
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SVA-mediated chromatin re-organization in XDP
Jakobsson, J. (PI) & Horvath, V. (Researcher)
The Collaborative Center for X-Linked Dystonia-Parkinsonism (CCXDP)
2021/07/01 → …
Project: Research
Activities
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Segerfalk Symposium 2024
Jakobsson, J. (Organiser), Douse, C. (Organiser), Horvath, V. (Organiser), Pettersson, P. (Organiser), Pombo, A. (Invited speaker), Bartosovic, M. (Invited speaker), Bayin, N. S. (Invited speaker), Rowe, H. M. (Invited speaker), Toda, T. (Invited speaker), Gerdes, P. (Chair), Dorazehi, F. (Chair), Castilla-Vallmanya, L. (Chair) & Garza, R. (Chair)
2024 May 15Activity: Participating in or organising an event › Organisation of conference
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Neuroscience Day 2024
Björklund, A. (Member of programme committee), Ekdahl Clementson, C. (Member of programme committee), Garwicz, M. (Member of programme committee), Norrving, B. (Member of programme committee), Parmar, M. (Member of programme committee), Petersén, Å. (Member of programme committee), Hansson, O. (Member of programme committee), COMPAGNO STRANDBERG, M. (Member of programme committee), Ottosson, D. (Member of programme committee), Heuer, A. (Member of programme committee), Kokaia, M. (Member of programme committee), Mårtensson, J. (Member of programme committee), Castilla-Vallmanya, L. (Member of programme committee), Pettersson, P. (Organiser), Jakobsson, J. (Chair), Castilla-Vallmanya, L. (Organiser), Twohig, D. P. (Contributor), Cesaroni, V. (Contributor), Fernandez Calle, R. (Contributor), Arenas, E. (Invited speaker), Lignani, G. (Invited speaker), Beyeler, A. (Invited speaker), Adami, A. (Presenter), Bergh, S. (Presenter), Fritze, J. (Presenter), Hägg, A. (Presenter), Jukkola, J. (Presenter), Sozzi, E. (Presenter), Tampé, J. (Presenter), Schaefer, A. (Keynote/plenary speaker), Habekost, M. (Chair) & Wickham, J. (Chair)
2024 May 7Activity: Participating in or organising an event › Organisation of conference
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LUCC - CNS Webinar
Pietras, A. (Organiser), Bengzon, J. (Organiser) & Jakobsson, J. (Speaker)
2024 May 3Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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Supervision of PhD student: Carrie Davis-Hansson
Jakobsson, J. (First/primary/lead supervisor), Douse, C. (Second supervisor) & Parmar, M. (Supervisory team member)
2024 Mar 1 → 2028Activity: Examination and supervision › Supervision of PhD students
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The role of autophagy and transposable elements in human brain ageing
Pircs, K. (First/primary/lead supervisor), Jakobsson, J. (Second supervisor) & Sharma, Y. (Third supervisor)
2022 Aug 1 → 2026 Aug 1Activity: Examination and supervision › Supervision of PhD students
Prizes and Distinction
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Neurofortis Young Investigator Award
Jakobsson, J. (Recipient), 2010
Prize: Prize (including medals and awards)
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